(Q37463973)

20 August 2017

Abnormal Ras signaling in Costello syndrome (CS) negatively regulates enamel formation (English)

1 reference

20 August 2017

1 reference

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Ophir D Klein

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

author name string

Alice F Goodwin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

William E Tidyman

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Andrew H Jheon

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Amnon Sharir

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Xu Zheng

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Cyril Charles

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

James A Fagin

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Martin McMahon

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Bernhard Ganss

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Katherine A Rauen

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

publication date

20 September 2013

1 reference

20 August 2017

Human Molecular Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

page(s)

682-692

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

14 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3888259/fullTextXML

inferred from PubMed Central ID database lookup

cites work

From molecules to mastication: the development and evolution of teeth

1 reference

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BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor.

23 August 2017

1 reference

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MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors.

23 August 2017

1 reference

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Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice

23 August 2017

1 reference

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Craniofacial and dental development in cardio-facio-cutaneous syndrome: the importance of Ras signaling homeostasis

23 August 2017

1 reference

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NIH Image to ImageJ: 25 years of image analysis

23 August 2017

1 reference

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K-Ras and B-Raf oncogenes inhibit colon epithelial polarity establishment through up-regulation of c-myc

23 August 2017

1 reference

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Sox2+ stem cells contribute to all epithelial lineages of the tooth via Sfrp5+ progenitors

23 August 2017

1 reference

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Continual low-level MEK inhibition ameliorates cardio-facio-cutaneous phenotypes in zebrafish

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Epithelial-specific knockout of the Rac1 gene leads to enamel defects

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Evaluation of enamel pearls by cone-beam computed tomography (CBCT)

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Control of mitotic spindle angle by the RAS-regulated ERK1/2 pathway determines lung tube shape

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Costello and cardio-facio-cutaneous syndromes: Moving toward clinical trials in RASopathies

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

PERP regulates enamel formation via effects on cell-cell adhesion and gene expression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Peripheral calcifying odontogenic cyst: a case report and review of the literature

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Caries Detection Methods Based on Changes in Optical Properties between Healthy and Carious Tissue

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Noonan syndrome is associated with enhanced pERK activity, the repression of which can prevent craniofacial malformations

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Endogenous expression of Hras(G12V) induces developmental defects and neoplasms with copy number imbalances of the oncogene

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Enamel formation and amelogenesis imperfecta

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

HRAS and the Costello syndrome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Oral findings in 58 adults with tuberous sclerosis complex

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Sprouty genes control diastema tooth development via bidirectional antagonism of epithelial-mesenchymal FGF signaling

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

FGF signalling in craniofacial development and developmental disorders

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Genotype-phenotype correlation in Costello syndrome: HRAS mutation analysis in 43 cases.

23 August 2017

1 reference

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Amelotin--a Novel Secreted, Ameloblast-specific Protein

23 August 2017

1 reference

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Germline mutations in HRAS proto-oncogene cause Costello syndrome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Ameloblastin is a cell adhesion molecule required for maintaining the differentiation state of ameloblasts

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

The cutting-edge of mammalian development; how the embryo makes teeth

23 August 2017

1 reference

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Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Phosphoinositide 3-kinase-dependent activation of Rac.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Amelogenin-deficient mice display an amelogenesis imperfecta phenotype

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Reiterative signaling and patterning during mammalian tooth morphogenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

A new syndrome: mental subnormality and nasal papillomata

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Therapeutic strategies for targeting ras proteins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Characterization of Apin, a secreted protein highly expressed in tooth-associated epithelia

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Revitalization of a diastemal tooth primordium in Spry2 null mice results from increased proliferation and decreased apoptosis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Further delineation of Costello syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

ERK inhibition rescues defects in fate specification of Nf1-deficient neural progenitors and brain abnormalities

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

E-cadherin regulates the behavior and fate of epithelial stem cells and their progeny in the mouse incisor

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Localization of putative stem cells in dental epithelium and their association with Notch and FGF signaling.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Quantitative analysis of cell turnover in the enamel organ of the rat incisor. Evidence for ameloblast death immediately after enamel matrix secretion

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Epithelial fibroblast growth factor receptor 1 regulates enamel formation.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

HRAS mutations in Costello syndrome: detection of constitutional activating mutations in codon 12 and 13 and loss of wild-type allele in malignancy.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

HRAS mutation analysis in Costello syndrome: genotype and phenotype correlation.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Fgf-2 regulates enamel and dentine formation in mouse tooth germ.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888259

Cellular renewal in the enamel organ and the odontoblast layer of the rat incisor as followed by radioautography using3H-thymidine

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24057668

12 December 2020

inferred from PubMed ID database lookup

Male-to-male transmission of Costello syndrome: G12S HRAS germline mutation inherited from a father with somatic mosaicism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24057668

12 December 2020

inferred from PubMed ID database lookup

Ras regulates neuronal polarity via the PI3-kinase/Akt/GSK-3beta/CRMP-2 pathway

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24057668

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1093/HMG/DDT455

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

PubMed publication ID

24057668

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24057668%20AND%20SRC:MED&resulttype=core&format=json