(Q37485864)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

CSF Presenilin-1 complexes are increased in Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

0 references

María-Salud García-Ayllón

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Gunnar Brinkmalm

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Carlos A. Saura

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Javier Sáez

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

María-Letizia Campanari

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Alberto Rábano

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Jordi Alom

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Niels Andreasen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Kaj Blennow

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

publication date

6 August 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

Acta Neuropathologica Communications

1 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

page(s)

46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1186/2051-5960-1-46

1 March 2020

exact match

0 references

cites work

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23 August 2017

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23 August 2017

1 reference

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23 August 2017

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23 August 2017

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Active gamma-secretase complexes contain only one of each component

23 August 2017

1 reference

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Assembly, trafficking and function of gamma-secretase

23 August 2017

1 reference

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23 August 2017

1 reference

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A nine-transmembrane domain topology for presenilin 1

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations

23 August 2017

1 reference

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CSF markers for incipient Alzheimer's disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation

23 August 2017

1 reference

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gamma-Secretase inhibitors as molecular probes of presenilin function

23 August 2017

1 reference

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Detection of the presenilin 1 COOH-terminal fragment in the extracellular compartment: a release enhanced by apoptosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

APP processing and synaptic plasticity in presenilin-1 conditional knockout mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Brain expression of presenilins in sporadic and early-onset, familial Alzheimer's disease.

23 August 2017

1 reference

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The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues

23 August 2017

1 reference

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Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

23 August 2017

1 reference

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Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

23 August 2017

1 reference

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Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

23 August 2017

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Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form

23 August 2017

1 reference

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Changes in acetylcholinesterase expression are associated with altered presenilin-1 levels.

23 August 2017

1 reference

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Abnormal gel-electrophoretic behavior of presenilin 1 and it's fragment

6 September 2017

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Gamma-secretase exists on the plasma membrane as an intact complex that accepts substrates and effects intramembrane cleavage

14 September 2017

1 reference

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The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex

14 September 2017

1 reference

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Neuronal localization of presenilin-1 and association with amyloid plaques and neurofibrillary tangles in Alzheimer's disease.

28 September 2017

1 reference

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Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins.

26 June 2018

1 reference

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BACE1 levels correlate with phospho-tau levels in human cerebrospinal fluid

26 June 2018

1 reference

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Biomarkers in Alzheimer's disease drug development.

2 September 2018

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Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease.

2 September 2018

1 reference

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BACE1 activity in cerebrospinal fluid and its relation to markers of AD pathology

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Detection of a soluble form of BACE-1 in human cerebrospinal fluid by a sensitive activity assay.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Intraperitoneal administration of 340 kDa human plasma butyrylcholinesterase increases the level of the enzyme in the cerebrospinal fluid of rats.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Protein markers for Alzheimer disease in the frontal cortex and cerebellum.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Presenilins mutated at Asp-257 or Asp-385 restore Pen-2 expression and Nicastrin glycosylation but remain catalytically inactive in the absence of wild type Presenilin

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Partial Purification and Characterization of γ-Secretase from Post-mortem Human Brain

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Reconstitution of gamma-secretase activity

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Reduced expression of amyloid precursor protein, presenilin-1 and rab3a in cortical brain regions in Alzheimer's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

The expression of presenilin 1 mRNA in skin fibroblasts and brains from sporadic Alzheimer's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Expression of presenilin 1 mRNA in rat peripheral organs and brain

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Alzheimer's disease-associated presenilin 1 in neuronal cells: evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Quantification of presenilin-1 mRNA in Alzheimer's disease brains.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Interlaboratory comparison of neuropathology assessments in Alzheimer's disease: a study of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3893612

Presenilin Proteins Undergo Heterogeneous Endoproteolysis between Thr291and Ala299and Occur as Stable N- and C-Terminal Fragments in Normal and Alzheimer Brain Tissue

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F2051-5960-1-46

Evidence That Intramolecular Associations between Presenilin Domains Are Obligatory for Endoproteolytic Processing

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F2051-5960-1-46

Oligomerization of human presenilin-1 fragments

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24252417

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/2051-5960-1-46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

24252417

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252417%20AND%20SRC:MED&resulttype=core&format=json