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Glucocorticoid resistance in inflammatory diseases.
scientific article published on May 2009
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19482216
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482216%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
Glucocorticoid resistance in inflammatory diseases
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19482216
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482216%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
main subject
inflammation
0 references
glucocorticoid resistance
1 reference
based on heuristic
inferred from title
author
Ian M. Adcock
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19482216
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482216%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
author name string
Peter J Barnes
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19482216
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482216%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
language of work or name
English
0 references
publication date
1 May 2009
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19482216
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482216%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
published in
The Lancet
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19482216
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482216%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
volume
373
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19482216
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482216%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
issue
9678
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19482216
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482216%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
page(s)
1905-1917
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19482216
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482216%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
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Relative corticosteroid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma
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Glucocorticoid resistance in inflammatory bowel disease
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Predicting therapeutic outcome in severe ulcerative colitis by measuring in vitro steroid sensitivity of proliferating peripheral blood lymphocytes
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Apoptosis of lymphocytes induced by glucocorticoids and relationship to therapeutic efficacy in patients with systemic lupus erythematosus.
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Superantigens, steroid insensitivity and innate immunity in atopic eczema
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Inhaled corticosteroids for stable chronic obstructive pulmonary disease
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7 January 2021
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Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD
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Effect of High Dose Inhaled Steroid on Cells, Cytokines, and Proteases in Induced Sputum in Chronic Obstructive Pulmonary Disease
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Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease
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Partial reversibility of airflow limitation and increased exhaled NO and sputum eosinophilia in chronic obstructive pulmonary disease
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Do inhaled corticosteroids impair long-term growth in prepubertal cystic fibrosis patients?
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Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects
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How corticosteroids control inflammation: Quintiles Prize Lecture 2005
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Antiinflammatory action of glucocorticoids--new mechanisms for old drugs
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7 January 2021
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Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells
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The physiology of human glucocorticoid receptor beta (hGRbeta) and glucocorticoid resistance.
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Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12.
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Corticosteroid effects on cell signalling
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MAP kinase phosphatase 1: a novel mediator of biological effects of glucocorticoids?
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Negative glucocorticoid receptor response elements and their role in glucocorticoid action
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Histone acetylation and deacetylation: importance in inflammatory lung diseases
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Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression
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HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor
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Glucocorticoid inhibition of granulocyte macrophage-colony-stimulating factor from T cells is independent of control by nuclear factor-kappaB and conserved lymphokine element 0.
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Glucocorticoids regulate tristetraprolin synthesis and posttranscriptionally regulate tumor necrosis factor alpha inflammatory signaling.
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Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients
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Use of gene expression profiling to identify a novel glucocorticoid sensitivity determining gene, BMPRII.
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Chemical mutational analysis of the human glucocorticoid receptor cDNA in glucocorticoid-resistant bronchial asthma.
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Glucocorticoid receptor polymorphism affects transrepression but not transactivation
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Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy
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7 January 2021
based on heuristic
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p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma
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Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients
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7 January 2021
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p38 Mitogen-activated protein kinase (MAPK) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: correlation between p38 MAPK activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211.
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Inhibition of glucocorticoid receptor-mediated transcriptional activation by p38 mitogen-activated protein (MAP) kinase
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Steroid receptor phosphorylation: a key modulator of multiple receptor functions
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7 January 2021
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A role for STAT5 in the pathogenesis of IL-2-induced glucocorticoid resistance
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Modulation of glucocorticoid receptor function via phosphorylation.
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7 January 2021
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Superantigen-induced corticosteroid resistance of human T cells occurs through activation of the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK-ERK) pathway
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7 January 2021
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Inhibition of glucocorticoid receptor binding by nitric oxide
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Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids.
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Increased glucocorticoid receptor beta in airway cells of glucocorticoid-insensitive asthma.
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Glucocorticoid resistance in asthma is associated with elevated in vivo expression of the glucocorticoid receptor beta-isoform
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Glucocorticoid receptor alpha and beta in glucocorticoid dependent asthma
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https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
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7 January 2021
based on heuristic
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Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative beta isoform: a mechanism for the generation of glucocorticoid resistance.
1 reference
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7 January 2021
based on heuristic
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Microbial superantigens induce glucocorticoid receptor beta and steroid resistance in a nasal explant model
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7 January 2021
based on heuristic
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Increased glucocorticoid receptor beta alters steroid response in glucocorticoid-insensitive asthma
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https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human glucocorticoid receptor beta binds RU-486 and is transcriptionally active.
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7 January 2021
based on heuristic
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Abnormal glucocorticoid receptor-activator protein 1 interaction in steroid-resistant asthma
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7 January 2021
based on heuristic
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Systemic glucocorticoid reduces bronchial mucosal activation of activator protein 1 components in glucocorticoid-sensitive but not glucocorticoid-resistant asthmatic patients
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https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
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7 January 2021
based on heuristic
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Corticosteroid-resistant bronchial asthma is associated with increased c-fos expression in monocytes and T lymphocytes
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7 January 2021
based on heuristic
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Cytoskeletal and cell contact control of the glucocorticoid pathway
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of nonmuscle cofilin-1 and steroid responsiveness in severe asthma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased histone deacetylase activity in chronic obstructive pulmonary disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced histone deacetylase in COPD: clinical implications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative stress and redox regulation of lung inflammation in COPD.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory T cells and IL-10 in allergic inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overcoming drug resistance induced by P-glycoprotein on lymphocytes in patients with refractory rheumatoid arthritis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of 3435C>T MDR1 gene polymorphism on rheumatoid arthritis treatment with disease-modifying antirheumatic drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The macrophage migration inhibitory factor-glucocorticoid dyad: regulation of inflammation and immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Macrophage migration inhibitory factor promotes innate immune responses by suppressing glucocorticoid-induced expression of mitogen-activated protein kinase phosphatase-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Macrophage migration inhibitory factor has a proinflammatory activity via the p38 pathway in glucocorticoid-resistant ulcerative colitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of disease: macrophage migration inhibitory factor in SLE, RA and atherosclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory role for macrophage migration inhibitory factor in acute respiratory distress syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF). Potential role in asthma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective glucocorticoid receptor agonists (SEGRAs): novel ligands with an improved therapeutic index.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Colectomy rate in steroid-refractory colitis initially responsive to cyclosporin: a long-term retrospective cohort study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclosporine and tacrolimus for the treatment of rheumatoid arthritis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38alpha-selective mitogen-activated protein kinase inhibitor SD-282 reduces inflammation in a subchronic model of tobacco smoke-induced airway inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is there a future for small molecule drugs in the treatment of rheumatic diseases?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 MAP-kinases pathway regulation, function and role in human diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The IKK NF-kappa B system: a treasure trove for drug development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of smoking cessation on lung function and airway inflammation in smokers with asthma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Basiliximab for the treatment of steroid-resistant ulcerative colitis: further experience in moderate and severe disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacological strategies for overcoming multidrug resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Macrophage migration inhibitory factor: a therapeutic target across inflammatory diseases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting phosphoinositide 3-kinase: moving towards therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting histone deacetylase 2 in chronic obstructive pulmonary disease treatment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2809%2960326-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0140-6736(09)60326-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19482216
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482216%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PubMed publication ID
19482216
1 reference
stated in
Europe PubMed Central
PubMed publication ID
19482216
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19482216%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
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