(Q37537359)

20 August 2017

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title

Telomeres and telomerase in chronic myeloid leukaemia: impact for pathogenesis, disease progression and targeted therapy (English)

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20 August 2017

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Gunhild Keller

1

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20 August 2017

Ute Brassat

2

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20 August 2017

Melanie Braig

3

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20 August 2017

Denise Heim

4

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20 August 2017

Henning Wege

5

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20 August 2017

Tim H Brümmendorf

6

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20 August 2017

publication date

1 September 2009

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20 August 2017

published in

Hematological Oncology

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20 August 2017

volume

27

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20 August 2017

issue

3

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20 August 2017

page(s)

123-129

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Specific telomere dysfunction induced by GRN163L increases radiation sensitivity in breast cancer cells

20 August 2017

cites work

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Mammalian telomeres end in a large duplex loop

21 January 2018

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7 January 2021

Telomere states and cell fates

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7 January 2021

Tiptoeing to chromosome tips: facts, promises and perils of today's human telomere biology

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7 January 2021

Shelterin: the protein complex that shapes and safeguards human telomeres

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7 January 2021

Telomeres shorten during ageing of human fibroblasts

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7 January 2021

The telomere hypothesis of cellular aging

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7 January 2021

Telomere dysfunction and tumour suppression: the senescence connection

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7 January 2021

Telomerase and differentiation in multicellular organisms: turn it off, turn it on, and turn it off again

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7 January 2021

Mammalian telomeres and telomerase

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7 January 2021

Human is a unique species among primates in terms of telomere length.

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7 January 2021

Telomere length in leukocyte subpopulations of patients with aplastic anemia

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7 January 2021

Telomere length in myelodysplastic syndromes

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7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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7 January 2021

Essential role of mouse telomerase in highly proliferative organs

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7 January 2021

The RNA component of human telomerase

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7 January 2021

Telomerase catalytic subunit homologs from fission yeast and human

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7 January 2021

Formation of de novo centromeres and construction of first-generation human artificial microchromosomes

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7 January 2021

Regulation of the human telomerase reverse transcriptase gene

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7 January 2021

Telomere and telomerase in stem cells

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7 January 2021

A survey of telomerase activity in human cancer

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7 January 2021

Regulation of telomere length and telomerase in T and B cells: a mechanism for maintaining replicative potential

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7 January 2021

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7 January 2021

Molecular mechanisms of transformation by the BCR-ABL oncogene

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7 January 2021

Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

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7 January 2021

Telomere shortening correlates with prognostic score at diagnosis and proceeds rapidly during progression of chronic myeloid leukemia

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7 January 2021

Telomere length shortening is associated with disease evolution in chronic myelogenous leukemia.

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7 January 2021

Telomerase activity and cytogenetic changes in chronic myeloid leukemia with disease progression.

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7 January 2021

Telomere dynamics and genetic instability in disease progression of chronic myeloid leukemia

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7 January 2021

Telomerase activity in normal and malignant hematopoietic cells

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7 January 2021

Telomeres and telomerase in hematologic neoplasia

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7 January 2021

DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?

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7 January 2021

Oxidative stress shortens telomeres

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7 January 2021

Dysregulated expression of the major telomerase components in leukaemic stem cells.

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7 January 2021

Lack of cell cycle regulation of telomerase activity in human cells

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7 January 2021

Telomerase activity: a biomarker of cell proliferation, not malignant transformation

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7 January 2021

The relationship between telomere length and therapy-associated cytogenetic responses in patients with chronic myeloid leukemia

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7 January 2021

The development of imatinib as a therapeutic agent for chronic myeloid leukemia

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7 January 2021

Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia

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7 January 2021

Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia

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7 January 2021

BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571.

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7 January 2021

Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study.

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7 January 2021

Telomere length in peripheral blood granulocytes reflects response to treatment with imatinib in patients with chronic myeloid leukemia

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7 January 2021

Telomere length and telomerase activity in the BCR-ABL-transformed murine Pro-B cell line BaF3 is unaffected by treatment with imatinib

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7 January 2021

hTERT, the catalytic component of telomerase, is downregulated in the haematopoietic stem cells of patients with chronic myeloid leukaemia

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7 January 2021

Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase

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7 January 2021

Cross-talk between Bcr-Abl tyrosine kinase, protein kinase C and telomerase-a potential reason for resistance to Glivec in chronic myelogenous leukaemia

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7 January 2021

Telomerase and cancer therapeutics

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7 January 2021

Inhibition of telomerase limits the growth of human cancer cells.

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7 January 2021

Telomerase inhibition enhances the response to anticancer drug treatment in human breast cancer cells

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7 January 2021

Telomerase is limiting the growth of acute myeloid leukemia cells.

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7 January 2021

Pharmacological telomerase inhibition can sensitize drug-resistant and drug-sensitive cells to chemotherapeutic treatment

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7 January 2021

A highly selective telomerase inhibitor limiting human cancer cell proliferation

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7 January 2021

Consequences of telomerase inhibition by BIBR1532 on proliferation and chemosensitivity of chondrosarcoma cell lines

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7 January 2021

Lipid modification of GRN163, an N3'-->P5' thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition

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7 January 2021

Telomerase inhibition impairs tumor growth in glioblastoma xenografts

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7 January 2021

Efficient inhibition of human telomerase reverse transcriptase expression by RNA interference sensitizes cancer cells to ionizing radiation and chemotherapy

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7 January 2021

Targeted therapy of human malignant glioma in a mouse model by 2-5A antisense directed against telomerase RNA.

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7 January 2021

Treatment of prostate cancer in vitro and in vivo with 2-5A-anti-telomerase RNA component.

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7 January 2021

2-5A antisense directed against telomerase RNA produces apoptosis in ovarian cancer cells

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7 January 2021

Telomerase inhibitors

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7 January 2021

Identifiers

DOI

10.1002/HON.901

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20 August 2017

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