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Noxa: at the tip of the balance between life and death.
scientific article published on December 2008
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3272398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19641509%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
review article
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stated in
Europe PubMed Central
title
Noxa: at the tip of the balance between life and death
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3272398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19641509%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
author
Christian Ploner
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3272398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19641509%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
author name string
R Kofler
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3272398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19641509%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
A Villunger
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
3272398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19641509%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
language of work or name
English
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publication date
1 December 2008
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Europe PubMed Central
PMCID
3272398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19641509%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PMCID
3272398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19641509%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
volume
27 Suppl 1
1 reference
stated in
Europe PubMed Central
PMCID
3272398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19641509%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
page(s)
S84-92
1 reference
stated in
Europe PubMed Central
PMCID
3272398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19641509%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
exact match
https://scigraph.springernature.com/pub.10.1038/onc.2009.46
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Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene
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BH3-only proteins Noxa, Bmf, and Bim are necessary for arsenic trioxide-induced cell death in myeloma
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In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute
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Tumor cell-selective regulation of NOXA by c-MYC in response to proteasome inhibition.
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Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1.
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23 August 2017
Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa.
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'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.
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The NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells
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23 August 2017
The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells
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Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis
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Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins
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23 August 2017
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
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23 August 2017
E1A activates transcription of p73 and Noxa to induce apoptosis
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PubMed Central
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Role of histone H2A ubiquitination in Polycomb silencing
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23 August 2017
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23 August 2017
BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha
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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
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23 August 2017
The Molecular Mechanism of Noxa-induced Mitochondrial Dysfunction in p53-Mediated Cell Death
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23 August 2017
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23 August 2017
Noxa in colorectal cancer: a study on DNA, mRNA and protein expression
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Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53
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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
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Molecular cloning and characterization of a cDNA for a novel phorbol-12-myristate-13-acetate-responsive gene that is highly expressed in an adult T-cell leukemia cell line
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23 August 2017
Identification and characterization of two splicing variants of human Noxa
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14 September 2017
Crosstalk among Bcl-2 family members in B-CLL: seliciclib acts via the Mcl-1/Noxa axis and gradual exhaustion of Bcl-2 protection.
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14 September 2017
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14 September 2017
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas
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14 September 2017
Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells
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14 September 2017
Puma(*)Mcl-1 interaction is not sufficient to prevent rapid degradation of Mcl-1.
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14 September 2017
Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation
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14 September 2017
Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis
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25 June 2018
The BCL2 rheostat in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3272398
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25 June 2018
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.
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PubMed Central
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25 June 2018
Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis
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PubMed Central
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25 June 2018
Tissue-specific induction of p53 targets in vivo.
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PubMed Central
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25 June 2018
HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function.
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1 September 2018
Identification of glucocorticoid-response genes in children with acute lymphoblastic leukemia
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PubMed Central
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1 September 2018
Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications.
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1 September 2018
Chronic lymphocytic leukemia cells display p53-dependent drug-induced Puma upregulation
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1 September 2018
Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.
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1 September 2018
Mutational analysis of Noxa gene in human cancers
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PubMed Central
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1 September 2018
Pro-apoptotic BH3-only Bcl-2 family members in vertebrate model organisms suitable for genetic experimentation
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31 March 2020
Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice
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31 March 2020
p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation
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31 March 2020
Identifiers
DOI
10.1038/ONC.2009.46
1 reference
stated in
Europe PubMed Central
PMCID
3272398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19641509%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
PMCID
3272398
1 reference
stated in
Europe PubMed Central
PMCID
3272398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19641509%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
PubMed ID
19641509
1 reference
stated in
Europe PubMed Central
PMCID
3272398
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19641509%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
ResearchGate publication ID
26704263
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