(Q37600686)

21 August 2017

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title

Epigenetic factors in aging and longevity (English)

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21 August 2017

2

Jan Vijg

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21 August 2017

Silvia Gravina

1

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21 August 2017

19 September 2009

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21 August 2017

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21 August 2017

459

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21 August 2017

2

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21 August 2017

247-258

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https://scigraph.springernature.com/pub.10.1007/s00424-009-0730-7

21 August 2017

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cites work

Does damage to DNA and other macromolecules play a role in aging? If so, how?

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0730-7

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0730-7

Epigenetics and human disease: translating basic biology into clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0730-7

DeltaNp63alpha overexpression induces downregulation of Sirt1 and an accelerated aging phenotype in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0730-7

Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome

21 January 2018

1 reference

12 December 2020

Chromosomal Instability and Tumors Promoted by DNA Hypomethylation

1 reference

12 December 2020

Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging

1 reference

12 December 2020

5-Azacytidine-induced demethyelation of DNA to senescent level does not block proliferation of human fibroblasts

1 reference

12 December 2020

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

1 reference

12 December 2020

A pipeline for the quantitative analysis of CG dinucleotide methylation using mass spectrometry

1 reference

12 December 2020

Epigenetics as a mechanism driving polygenic clinical drug resistance

1 reference

12 December 2020

Drawing the line in progeria syndromes

1 reference

12 December 2020

Telomeres shorten during ageing of human fibroblasts

1 reference

12 December 2020

Epigenetic dynamics of imprinted X inactivation during early mouse development

1 reference

12 December 2020

Increased cell-to-cell variation in gene expression in ageing mouse heart

1 reference

12 December 2020

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

1 reference

12 December 2020

Werner and Hutchinson-Gilford progeria syndromes: mechanistic basis of human progeroid diseases.

1 reference

12 December 2020

Hallmarks of senescence in carcinogenesis and cancer therapy

1 reference

12 December 2020

Chromosomal inheritance of epigenetic states in fission yeast during mitosis and meiosis

1 reference

12 December 2020

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

1 reference

12 December 2020

Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug

1 reference

12 December 2020

L1 and HERV-W retrotransposons are hypomethylated in human ovarian carcinomas

1 reference

12 December 2020

Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis

1 reference

12 December 2020

The inheritance of acquired epigenetic variations

1 reference

12 December 2020

5-Azacytidine-induced undercondensations in human chromosomes

1 reference

12 December 2020

Epigenetic transgenerational actions of endocrine disruptors and male fertility

1 reference

12 December 2020

Hairpin-bisulfite PCR: assessing epigenetic methylation patterns on complementary strands of individual DNA molecules.

1 reference

12 December 2020

1 reference

12 December 2020

DNA methylation and cancer

1 reference

12 December 2020

Age-specific epigenetic drift in late-onset Alzheimer's disease

1 reference

12 December 2020

Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

1 reference

12 December 2020

Methods to detect biomarkers of cellular senescence: the senescence-associated beta-galactosidase assay

1 reference

12 December 2020

Epigenetic regulation of an IAP retrotransposon in the aging mouse: progressive demethylation and de-silencing of the element by its repetitive induction

1 reference

12 December 2020

Epigenetic drift in aging identical twins

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12 December 2020

Unravelling heterochromatin: competition between positive and negative factors regulates accessibility

1 reference

12 December 2020

Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome

1 reference

12 December 2020

Imprinting and the epigenetic asymmetry between parental genomes.

1 reference

12 December 2020

Evidence that diet modification reduces in vivo oxidant damage

1 reference

12 December 2020

Dynamic reprogramming of DNA methylation in the early mouse embryo.

1 reference

12 December 2020

Processing the H3K36me3 signature

1 reference

12 December 2020

Assignment of cytosine-5 DNA methyltransferases Dnmt3a and Dnmt3b to mouse chromosome bands 12A2-A3 and 2H1 by in situ hybridization

1 reference

12 December 2020

The inheritance of epigenetic defects

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12 December 2020

Epigenetic reprogramming in mammalian development

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12 December 2020

Genomic instability in laminopathy-based premature aging

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12 December 2020

Fetal origins of adult disease

1 reference

12 December 2020

ChIP-chip: considerations for the design, analysis, and application of genome-wide chromatin immunoprecipitation experiments

1 reference

12 December 2020

Vascular cell senescence: contribution to atherosclerosis

1 reference

12 December 2020

Epigenetic differences arise during the lifetime of monozygotic twins

1 reference

12 December 2020

Cancer, aging and cellular senescence

1 reference

12 December 2020

Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging

1 reference

12 December 2020

Genomic 5-methyldeoxycytidine decreases with age.

1 reference

12 December 2020

Melanotic neuroectodermal tumor of the epididymis. A case report

1 reference

12 December 2020

DNA methylation, methyltransferases, and cancer

1 reference

12 December 2020

Diverse and dynamic functions of the Sir silencing complex

1 reference

12 December 2020

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

1 reference

12 December 2020

Cancer epigenetics comes of age

1 reference

12 December 2020

Aberrant methylation in pediatric myelodysplastic syndrome.

1 reference

12 December 2020

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

1 reference

12 December 2020

The Frequency of Translocations Produced by X-Rays in Drosophila

1 reference

12 December 2020

Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (Igf2) locus

1 reference

12 December 2020

Comparative isoschizomer profiling of cytosine methylation: the HELP assay

1 reference

12 December 2020

Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

1 reference

12 December 2020

Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse.

1 reference

12 December 2020

Epigenetics meets next-generation sequencing

1 reference

12 December 2020

Epigenetics of complex diseases: from general theory to laboratory experiments.

1 reference

12 December 2020

Cellular senescence: when bad things happen to good cells

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12 December 2020

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12 December 2020

Enhanced histone acetylation and transcription: a dynamic perspective

1 reference

12 December 2020

Large genome rearrangements as a primary cause of aging

1 reference

12 December 2020

Promoter hypermethylation--can this change alone ever designate true tumor suppressor gene function?

1 reference

12 December 2020

The Hutchinson-Gilford progeria syndrome. Report of 4 cases and review of the literature

1 reference

12 December 2020

Intra-individual change over time in DNA methylation with familial clustering

1 reference

12 December 2020

Transgenerational inheritance of epigenetic states at the murine Axin(Fu) allele occurs after maternal and paternal transmission

1 reference

12 December 2020

DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein

1 reference

12 December 2020

Genome dynamics and transcriptional deregulation in aging

1 reference

12 December 2020

DNA hypermethylation in tumorigenesis: epigenetics joins genetics

1 reference

12 December 2020

The epigenetic progenitor origin of human cancer

1 reference

12 December 2020

Dysdifferentiative nature of aging: age-dependent expression of MuLV and globin genes in thymus, liver and brain in the AKR mouse strain.

1 reference

12 December 2020

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

1 reference

12 December 2020

DNA methyltransferase inhibition in normal human fibroblasts induces a p21-dependent cell cycle withdrawal

1 reference

12 December 2020

Induction of Tumors in Mice by Genomic Hypomethylation

1 reference

12 December 2020

[Intragenomic specificity of DNA methylation in animals. Qualitative differences in tissues and changes in methylation of repeating sequences during aging, carcinogenesis and hormonal induction]

1 reference

12 December 2020

DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons

1 reference

12 December 2020

Heterochromatin: new possibilities for the inheritance of structure

1 reference

12 December 2020

Mutation frequency and type during ageing in mouse seminiferous tubules

1 reference

12 December 2020

Epigenetic aspects of cellular senescence

1 reference

12 December 2020

Early Environmental Regulation of Hippocampal Glucocorticoid Receptor Gene Expression: Characterization of Intracellular Mediators and Potential Genomic Target Sites

1 reference

12 December 2020

Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction

1 reference

12 December 2020

Aging and cancer-related loss of insulin-like growth factor 2 imprinting in the mouse and human prostate

1 reference

12 December 2020

Epigenetic inheritance at the agouti locus in the mouse

1 reference

12 December 2020

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

1 reference

12 December 2020

Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase.

1 reference

12 December 2020

Epigenetics at the epicenter of modern medicine

1 reference

12 December 2020

Chromatin conversations: mechanisms and implications of paramutation

1 reference

12 December 2020

Epimutations in Prader-Willi and Angelman syndromes: a molecular study of 136 patients with an imprinting defect

1 reference

12 December 2020

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

1 reference

12 December 2020

Sex-specific, male-line transgenerational responses in humans

1 reference

12 December 2020

Lamin A-dependent nuclear defects in human aging

1 reference

12 December 2020

Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter

1 reference

12 December 2020

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

1 reference

12 December 2020

Gene-nutrient interactions and DNA methylation

1 reference

12 December 2020

The multistep nature of cancer

1 reference

12 December 2020

Resveratrol improves health and survival of mice on a high-calorie diet

1 reference

12 December 2020

Cellular senescence, cancer and aging: the telomere connection

1 reference

12 December 2020

In utero exposure to famine and subsequent fertility: The Dutch Famine Birth Cohort Study

1 reference

12 December 2020

Telomere positional effects and the regulation of cellular senescence

1 reference

12 December 2020

Extrachromosomal rDNA circles--a cause of aging in yeast

1 reference

12 December 2020

Aging, DNA methylation and cancer

1 reference

12 December 2020

Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains

1 reference

12 December 2020

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

1 reference

12 December 2020

Age-associated activation of epigenetically repressed genes in the mouse

1 reference

12 December 2020

Dysdifferentiative nature of aging: passage number dependency of globin gene expression in normal human diploid cells grown in tissue culture

1 reference

12 December 2020

Mutation accumulation in vivo and the importance of genome stability in aging and cancer.

1 reference

12 December 2020

Infrequent occurrence of age-dependent changes in CpG island methylation as detected by restriction landmark genome scanning

1 reference

12 December 2020

10.1007/S00424-009-0730-7

Identifiers

DOI

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21 August 2017

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PubMed ID

19768466