(Q37605889)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793002%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

review article

1 reference

title

cIAP2 as a therapeutic target in colorectal cancer and other malignancies (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793002%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793002%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

3

Iwao Sasaki

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793002%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

2

Hideaki Karasawa

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793002%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

language of work or name

English

0 references

publication date

1 November 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793002%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

8 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793002%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793002%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793002%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

1333-1345

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793002%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

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Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group

21 January 2018

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Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer

21 January 2018

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Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

21 January 2018

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Proteases for cell suicide: functions and regulation of caspases

21 January 2018

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The protein structures that shape caspase activity, specificity, activation and inhibition

21 January 2018

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A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

21 January 2018

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The inhibitor of apoptosis proteins as therapeutic targets in cancer

21 January 2018

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Down-regulation of cIAP2 enhances 5-FU sensitivity through the apoptotic pathway in human colon cancer cells

21 January 2018

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The inhibitors of apoptosis (IAPs) as cancer targets

21 January 2018

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Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat

21 January 2018

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NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP

21 January 2018

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The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

21 January 2018

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Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

21 January 2018

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IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis

21 January 2018

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Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

21 January 2018

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Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors

21 January 2018

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MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression

21 January 2018

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Genomic organization and physical map of the human inhibitors of apoptosis: HIAP1 and HIAP2

21 January 2018

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Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo

21 January 2018

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The RING domain of cIAP1 mediates the degradation of RING-bearing inhibitor of apoptosis proteins by distinct pathways

21 January 2018

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Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation

21 January 2018

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Genetic alterations during colorectal-tumor development

21 January 2018

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Identification of FAP locus genes from chromosome 5q21

21 January 2018

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Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

21 January 2018

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Subcellular expression of c-IAP1 and c-IAP2 in colorectal cancers: relationships with clinicopathological features and prognosis

21 January 2018

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Expression of IAP family proteins in colon cancers from patients with different age groups

21 January 2018

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Analysis of apoptosis protein expression in early-stage colorectal cancer suggests opportunities for new prognostic biomarkers

21 January 2018

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 January 2018

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Colon cancer and apoptosis.

21 January 2018

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Expression of Bcl-XS alters cytokinetics and decreases clonogenic survival in K12 rat colon carcinoma cells

21 January 2018

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CD95's deadly mission in the immune system

21 January 2018

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The mitochondrial apoptosome: a killer unleashed by the cytochrome seas

21 January 2018

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IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

21 January 2018

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

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Cell death independent of caspases: a review.

21 January 2018

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IAP family protein expression correlates with poor outcome of multiple myeloma patients in association with chemotherapy-induced overexpression of multidrug resistance genes.

21 January 2018

1 reference

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Birc2 (cIap1) regulates endothelial cell integrity and blood vessel homeostasis.

21 January 2018

1 reference

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IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

21 January 2018

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cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

21 January 2018

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The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

21 January 2018

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Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

21 January 2018

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The alternative NF-kappaB pathway from biochemistry to biology: pitfalls and promises for future drug development

21 January 2018

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A small molecule ubiquitination inhibitor blocks NF-kappa B-dependent cytokine expression in cells and rats

21 January 2018

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Phase I study of YM155, a novel survivin suppressant, in patients with advanced solid tumors

21 January 2018

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Carrier-mediated uptake of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel small-molecule survivin suppressant, into human solid tumor and lymphoma cells

21 January 2018

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Structural basis of IAP recognition by Smac/DIABLO

21 January 2018

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A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death

21 January 2018

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Design, synthesis, and evaluation of potent, nonpeptidic mimetics of second mitochondria-derived activator of caspases

21 January 2018

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Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs

21 January 2018

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SM-164: a novel, bivalent Smac mimetic that induces apoptosis and tumor regression by concurrent removal of the blockade of cIAP-1/2 and XIAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903277256

Design, synthesis, and characterization of a potent, nonpeptide, cell-permeable, bivalent Smac mimetic that concurrently targets both the BIR2 and BIR3 domains in XIAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903277256

Potent, orally bioavailable diazabicyclic small-molecule mimetics of second mitochondria-derived activator of caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903277256

Recurrent overexpression of c-IAP2 in EBV-associated nasopharyngeal carcinomas: critical role in resistance to Toll-like receptor 3-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903277256

Cytoprotective effects of IAPs revealed by a small molecule antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903277256

IAP-targeted therapies for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903277256

Preclinical characterization of AEG35156/GEM 640, a second-generation antisense oligonucleotide targeting X-linked inhibitor of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903277256

Survivin antisense oligonucleotides effectively radiosensitize colorectal cancer cells in both tissue culture and murine xenograft models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903277256

Anti-adult T-cell leukemia effects of brown algae fucoxanthin and its deacetylated product, fucoxanthinol

21 January 2018

1 reference

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10.1517/14728220903277256

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793002%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference