(Q37611109)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19814820%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

review article

2 references

3 December 2020

Immunological considerations of modern animal models of malignant primary brain tumors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19814820%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

19 September 2019

1 reference

3 December 2020

1 reference

3 December 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19814820%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Michael E Sughrue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19814820%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Ari J Kane

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19814820%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Martin J Rutkowski

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19814820%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Shanna Fang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19814820%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

C David James

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19814820%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Andrew T Parsa

7

1 reference

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9 February 2020

publication date

8 October 2009

6 references

3 April 2019

25 April 2019

20 June 2019

19 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19814820%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

3 December 2020

Journal of Translational Medicine

6 references

3 April 2019

25 April 2019

20 June 2019

19 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19814820%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

3 December 2020

7

1 reference

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9 February 2020

page(s)

84

1 reference

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Creative Commons Attribution 2.0 Generic

9 February 2020

copyright license

5 references

3 April 2019

25 April 2019

20 June 2019

19 September 2019

on focus list of Wikimedia project

3 December 2020

copyright status

copyrighted

0 references

ScienceSource

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/1479-5876-7-84

0 references

cites work

Nestin and CD133: valuable stem cell-specific markers for determining clinical outcome of glioma patients.

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Genetically engineered mouse models of brain cancer and the promise of preclinical testing

23 August 2017

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p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

23 August 2017

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Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells

23 August 2017

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Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma

23 August 2017

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Pten haploinsufficiency accelerates formation of high-grade astrocytomas

23 August 2017

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Persistence of CD133+ cells in human and mouse glioma cell lines: detailed characterization of GL261 glioma cells with cancer stem cell-like properties

23 August 2017

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CD133+ neural stem cells in the ependyma of mammalian postnatal forebrain

23 August 2017

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BRCA2 is required for neurogenesis and suppression of medulloblastoma

23 August 2017

1 reference

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XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice

23 August 2017

1 reference

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Inactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response.

23 August 2017

1 reference

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Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN+/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase

23 August 2017

1 reference

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Negative regulation of CXCR4-mediated chemotaxis by the lipid phosphatase activity of tumor suppressor PTEN.

23 August 2017

1 reference

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New therapeutic target in inflammatory disease: macrophage migration inhibitory factor

23 August 2017

1 reference

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Growth differentiation factor-15/macrophage inhibitory cytokine-1 induction after kidney and lung injury

23 August 2017

1 reference

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

23 August 2017

1 reference

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The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling

23 August 2017

1 reference

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PTEN function: how normal cells control it and tumour cells lose it

23 August 2017

1 reference

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Blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation

23 August 2017

1 reference

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PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

23 August 2017

1 reference

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The INK4A/ARF locus: role in cell cycle control and apoptosis and implications for glioma growth

23 August 2017

1 reference

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Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress

23 August 2017

1 reference

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Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects

23 August 2017

1 reference

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A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

23 August 2017

1 reference

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Distinct patterns of Fas cell surface expression during development of T- or B-lymphocyte lineages in normal, scid, and mutant mice lacking or overexpressing p53, bcl-2, or rag-2 genes

23 August 2017

1 reference

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Epidermal growth factor receptor expression in oligodendroglial tumors.

23 August 2017

1 reference

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p53 is required for radiation-induced apoptosis in mouse thymocytes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Analysis of interleukin 2 and various effector cell populations in adoptive immunotherapy of 9L rat gliosarcoma: allogeneic cytotoxic T lymphocytes prevent tumor take

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

BMI1 sustains human glioblastoma multiforme stem cell renewal

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Antitumor activity of cytokine-induced killer cells in nude mouse xenograft model

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Experimental study on the treatment of intracerebral glioma xenograft with human cytokine-induced killer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Genomic changes and gene expression profiles reveal that established glioma cell lines are poorly representative of primary human gliomas

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Generation of human innate immune responses towards membrane macrophage colony stimulating factor (mM-CSF) expressing U251 glioma cells within immunodeficient (NIH-nu/beige/xid) mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Intracellular interferon triggers Jak/Stat signaling cascade and induces p53-dependent antiviral protection.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Interferons alpha and gamma induce p53-dependent and p53-independent apoptosis, respectively

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Rat brain tumor models in experimental neuro-oncology: the 9L, C6, T9, F98, RG2 (D74), RT-2 and CNS-1 gliomas

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

The p53-deficient mouse: a model for basic and applied cancer studies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Cytokine-induced endothelial arginase expression is dependent on epidermal growth factor receptor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Accelerated development and aging of the immune system in p53-deficient mice.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Role of NF-kappaB in the control of apoptotic and proliferative responses in IL-2-responsive T cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

A rat glioma model, CNS-1, with invasive characteristics similar to those of human gliomas: a comparison to 9L gliosarcoma

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Development of an animal brain tumor model and its response to therapy with 1,3-bis(2-chloroethyl)-1-nitrosourea.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

IFN-gamma induces apoptosis in developing mast cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Somatic induction of Pten loss in a preclinical astrocytoma model reveals major roles in disease progression and avenues for target discovery and validation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Hearing preservation after gamma knife stereotactic radiosurgery of vestibular schwannoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

p53 is a suppressor of inflammatory response in mice.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Epidermal growth factor enhances TNF-alpha-induced priming of human neutrophils

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

PTEN regulates motility but not directionality during leukocyte chemotaxis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Relation of epidermal growth factor receptor expression to mucus hypersecretion in diffuse panbronchiolitis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

The blockade of formyl peptide-induced respiratory burst by 2',5'-dihydroxy-2-furfurylchalcone involves phospholipase D signaling in neutrophils

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Complementary effects of platelet-derived growth factor autocrine stimulation and p53 or Ink4a-Arf deletion in a mouse glioma model.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Genetic determinants of malignancy in a mouse model for oligodendroglioma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Oligodendrogliomas result from the expression of an activated mutant epidermal growth factor receptor in a RAS transgenic mouse astrocytoma model.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Proliferative arrest and cell cycle regulation in CD8(+)CD28(-) versus CD8(+)CD28(+) T cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Inhibition of formyl-methionyl-leucyl-phenylalanine-stimulated respiratory burst by cirsimaritin involves inhibition of phospholipase D signaling in rat neutrophils

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Changes in the immunologic phenotype of human malignant glioma cells after passaging in vitro.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Increased expression of the INK4a/ARF locus in polycythemia vera

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Tumorigenesis in transgenic mice in which the SV40 T antigen is driven by the brain-specific FGF1 promoter.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Limitations of the C6/Wistar rat intracerebral glioma model: implications for evaluating immunotherapy.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Prolongation of survival of mice with glioma treated with semiallogeneic fibroblasts secreting interleukin-2.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Human ubiquitous JCV(CY) T-antigen gene induces brain tumors in experimental animals

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Systemic chemotherapy combined with local adoptive immunotherapy cures rats bearing 9L gliosarcoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Intracranial administrations of single or multiple source allogeneic cytotoxic T lymphocytes: chronic therapy for primary brain tumors.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

p53 controls proliferation of early B lineage cells by a p21 (WAF1/Cip1)-independent pathway.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

EGF mediates monocyte chemotaxis and macrophage proliferation and EGF receptor is expressed in atherosclerotic plaques

2 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2768693

Acquisition of the monocyte/macrophage phenotype in human mesangial cells

3 December 2018

1 reference

12 December 2020

Migration of activated lymphocytes when adoptively transferred into cannulated rat brain

1 reference

12 December 2020

The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma

1 reference

12 December 2020

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

1 reference

12 December 2020

p53 prevents maturation of T cell development to the immature CD4-CD8+ stage in Bcl11b-/- mice

1 reference

12 December 2020

Mechanisms that limit the in vitro proliferative potential of human CD8+ T lymphocytes

1 reference

12 December 2020

Reduced p53 in peripheral blood mononuclear cells from patients with rheumatoid arthritis is associated with loss of radiation-induced apoptosis

1 reference

12 December 2020

p53 is required for spontaneous autoantibody production in B6/lpr lupus mice

1 reference

12 December 2020

Identifiers

DOI

10.1186/1479-5876-7-84

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19814820%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19814820%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

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