(Q37633282)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19915166%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

review article

1 reference

title

The battlefield of perforin/granzyme cell death pathways (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19915166%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19915166%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Joseph A. Trapani

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19915166%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

author name string

Ilia Voskoboinik

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19915166%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

publication date

13 November 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19915166%20AND%20SRC:MED&resulttype=core&format=json

Journal of Leukocyte Biology

12 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19915166%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

87

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19915166%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19915166%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

page(s)

237-243

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19915166%20AND%20SRC:MED&resulttype=core&format=json

The orphan granzymes of humans and mice

12 February 2020

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The major human and mouse granzymes are structurally and functionally divergent

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Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis

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21 January 2018

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Perforin, a pore-forming protein detectable by monoclonal antibodies, is a functional marker for killer cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Chromosome transfer activates and delineates a locus control region for perforin.

21 January 2018

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Constitutive expression of pore-forming protein in peripheral blood gamma/delta T cells: implication for their cytotoxic role in vivo

21 January 2018

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Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).

21 January 2018

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Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo.

21 January 2018

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IL-2 regulates perforin and granzyme gene expression in CD8+ T cells independently of its effects on survival and proliferation

21 January 2018

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Induction of cytotoxic granules in human memory CD8+ T cell subsets requires cell cycle progression.

21 January 2018

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Induction of granzyme B and T cell cytotoxic capacity by IL-2 or IL-15 without antigens: multiclonal responses that are extremely lytic if triggered and short-lived after cytokine withdrawal

21 January 2018

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Interleukin 2 receptor signaling regulates the perforin gene through signal transducer and activator of transcription (Stat)5 activation of two enhancers

21 January 2018

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UVA induces granzyme B in human keratinocytes through MIF: implication in extracellular matrix remodeling.

21 January 2018

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Human keratinocytes acquire cellular cytotoxicity under UV-B irradiation. Implication of granzyme B and perforin

21 January 2018

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Granzyme K expressing cytotoxic T lymphocytes protects against influenza virus in granzyme AB-/- mice

21 January 2018

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Granzyme B-induced cell death exerted by ex vivo CTL: discriminating requirements for cell death and some of its signs

21 January 2018

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Cutting edge: rapid and efficient in vivo cytotoxicity by cytotoxic T cells is independent of granzymes A and B.

21 January 2018

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Measuring cell death mediated by cytotoxic lymphocytes or their granule effector molecules.

21 January 2018

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Perforin activity and immune homeostasis: the common A91V polymorphism in perforin results in both presynaptic and postsynaptic defects in function

21 January 2018

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Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis

21 January 2018

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Single-cell perforin and granzyme expression reveals the anatomical localization of effector CD8+ T cells in influenza virus-infected mice.

21 January 2018

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The genes for perforin, granzymes A-C and IFN-gamma are differentially expressed in single CD8(+) T cells during primary activation

21 January 2018

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Ultrastructural alteration of cytolytic T lymphocytes following their interaction with target cells. II. Morphogenesis of secretory granules and intracellular vacuoles

21 January 2018

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Ultrastructural alteration of cytolytic T lymphocytes following their interaction with target cells. I. Hypertrophy and change of orientation of the Golgi apparatus

21 January 2018

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Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes

21 January 2018

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Organelle proteomics: identification of the exocytic machinery associated with the natural killer cell secretory lysosome

21 January 2018

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A Proteomic Analysis of Lysosomal Integral Membrane Proteins Reveals the Diverse Composition of the Organelle

21 January 2018

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Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation

21 January 2018

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Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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A common fold mediates vertebrate defense and bacterial attack

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis

21 January 2018

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21 January 2018

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Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization.

21 January 2018

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Nuclear war: the granzyme A-bomb

21 January 2018

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Human and mouse granzyme A induce a proinflammatory cytokine response.

21 January 2018

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Extracellular activities of human granzymes. I. Granzyme A induces IL6 and IL8 production in fibroblast and epithelial cell lines

21 January 2018

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The inflammasomes: guardians of the body

21 January 2018

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Granzyme A is an interleukin 1 beta-converting enzyme

21 January 2018

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Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance

21 January 2018

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21 January 2018

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21 January 2018

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The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells

21 January 2018

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Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism

21 January 2018

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Activated CD4+CD25+ T cells selectively kill B lymphocytes

21 January 2018

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Granzyme M mediates a novel form of perforin-dependent cell death

21 January 2018

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NK cell protease granzyme M targets alpha-tubulin and disorganizes the microtubule network

21 January 2018

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Functional analysis of granzyme M and its role in immunity to infection

21 January 2018

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Granzyme H destroys the function of critical adenoviral proteins required for viral DNA replication and granzyme B inhibition

21 January 2018

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21 January 2018

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Cleavage of La protein by granzyme H induces cytoplasmic translocation and interferes with La-mediated HCV-IRES translational activity

21 January 2018

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The role of granzyme B cluster proteases in cell-mediated cytotoxicity

21 January 2018

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Granzyme C supports efficient CTL-mediated killing late in primary alloimmune responses

21 January 2018

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Cell death induced by granzyme C.

21 January 2018

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Structure of granzyme C reveals an unusual mechanism of protease autoinhibition

21 January 2018

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Cell surface-bound heat shock protein 70 (Hsp70) mediates perforin-independent apoptosis by specific binding and uptake of granzyme B.

21 January 2018

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Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin.

21 January 2018

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Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation

21 January 2018

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Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

21 January 2018

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Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin.

21 January 2018

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Granzyme K: a novel mediator in acute airway inflammation

21 January 2018

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Altered levels and molecular forms of granzyme k in plasma from septic patients.

21 January 2018

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