(Q37099923)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18314055%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

review article

1 reference

title

Measuring cell death mediated by cytotoxic lymphocytes or their granule effector molecules (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18314055%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

0 references

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18314055%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

author name string

Vivien R Sutton

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18314055%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Nigel J Waterhouse

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18314055%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Katherine Baran

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18314055%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Kylie Browne

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18314055%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Ilia Voskoboinik

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18314055%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

publication date

1 March 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18314055%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

Methods

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18314055%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

volume

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18314055%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

issue

3

1 reference

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3 January 2020

page(s)

241-249

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18314055%20AND%20SRC:MED&resulttype=core&format=json

Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis

3 January 2020

cites work

1 reference

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Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis

7 January 2021

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T cell receptor antagonist peptides induce positive selection

7 January 2021

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Processing of exogenous antigens for presentation by class I MHC molecules involves post-Golgi peptide exchange influenced by peptide-MHC complex stability and acidic pH.

7 January 2021

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Perforin-mediated target-cell death and immune homeostasis

7 January 2021

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Cytotoxic lymphocytes; instigators of dramatic target cell death.

7 January 2021

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Cytotoxic T lymphocytes: all roads lead to death

7 January 2021

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The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal

7 January 2021

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Perforin activity and immune homeostasis: the common A91V polymorphism in perforin results in both presynaptic and postsynaptic defects in function

7 January 2021

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A noncytotoxic mast cell tumor line exhibits potent IgE-dependent cytotoxicity after transfection with the cytolysin/perforin gene

7 January 2021

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The functional basis for hemophagocytic lymphohistiocytosis in a patient with co-inherited missense mutations in the perforin (PFN1) gene

7 January 2021

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A functional analysis of the putative polymorphisms A91V and N252S and 22 missense perforin mutations associated with familial hemophagocytic lymphohistiocytosis.

7 January 2021

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Rapid purification of cationic granule proteases: application to human granzymes

7 January 2021

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Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions

7 January 2021

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pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes.

7 January 2021

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Purification of natural killer cell cytotoxic granules for assaying target cell apoptosis.

7 January 2021

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Granzyme M mediates a novel form of perforin-dependent cell death

7 January 2021

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Calcium-dependent plasma membrane binding and cell lysis by perforin are mediated through its C2 domain: A critical role for aspartate residues 429, 435, 483, and 485 but not 491.

7 January 2021

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Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of them

7 January 2021

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The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes

7 January 2021

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Subsite specificities of granzyme M: a study of inhibitors and newly synthesized thiobenzyl ester substrates

7 January 2021

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Expression and purification of recombinant human granzyme B from Pichia pastoris

7 January 2021

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Expression and purification of enzymatically active recombinant granzyme B in a baculovirus system

7 January 2021

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Granzyme B/Perforin-Mediated Apoptosis of Jurkat Cells Results in Cleavage of Poly(ADP-ribose) Polymerase to the 89-kDa Apoptotic Fragment and Less Abundant 64-kDa Fragment

7 January 2021

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A central role for Bid in granzyme B-induced apoptosis

7 January 2021

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Functional dissociation of DeltaPsim and cytochrome c release defines the contribution of mitochondria upstream of caspase activation during granzyme B-induced apoptosis

7 January 2021

1 reference

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Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin

7 January 2021

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New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

7 January 2021

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Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway

7 January 2021

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A novel method for measuring CTL and NK cell-mediated cytotoxicity using annexin V and two-color flow cytometry

7 January 2021

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Granzyme B ELISPOT assay for ex vivo measurements of T cell immunity

7 January 2021

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The Granzyme B ELISPOT assay: an alternative to the 51Cr-release assay for monitoring cell-mediated cytotoxicity

7 January 2021

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Granzyme B; the chalk-mark of a cytotoxic lymphocyte

7 January 2021

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The fluorolysis assay, a highly sensitive method for measuring the cytolytic activity of T cells at very low numbers

7 January 2021

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Efficient Nuclear Targeting of Granzyme B and the Nuclear Consequences of Apoptosis Induced by Granzyme B and Perforin Are Caspase-dependent, but Cell Death Is Caspase-independent

7 January 2021

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Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

7 January 2021

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Granzyme A-deficient mice retain potent cell-mediated cytotoxicity.

7 January 2021

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Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

7 January 2021

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Functional analysis of granzyme M and its role in immunity to infection

7 January 2021

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In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A x B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells

7 January 2021

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A new mutation, gld, that produces lymphoproliferation and autoimmunity in C3H/HeJ mice

7 January 2021

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TRAIL-R as a negative regulator of innate immune cell responses.

7 January 2021

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DR5 knockout mice are compromised in radiation-induced apoptosis

7 January 2021

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Characterization of the in vivo function of TNF-alpha-related apoptosis-inducing ligand, TRAIL/Apo2L, using TRAIL/Apo2L gene-deficient mice

7 January 2021

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Tumor necrosis factor blockade in actively induced experimental autoimmune encephalomyelitis prevents clinical disease despite activated T cell infiltration to the central nervous system

7 January 2021

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Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

7 January 2021

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Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

7 January 2021

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A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

7 January 2021

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