(Q37642585)

21 August 2017

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title

From evolutionary genetics to human immunology: how selection shapes host defence genes (English)

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21 August 2017

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2

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21 August 2017

Luis B Barreiro

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publication date

1 December 2009

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21 August 2017

published in

Nature Reviews Genetics

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21 August 2017

volume

11

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21 August 2017

issue

1

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21 August 2017

page(s)

17-30

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https://scigraph.springernature.com/pub.10.1038/nrg2698

21 August 2017

exact match

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Natural selection on genes that underlie human disease susceptibility

31 March 2020

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Darwinian and demographic forces affecting human protein coding genes

31 March 2020

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31 March 2020

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Pyogenic bacterial infections in humans with MyD88 deficiency

31 March 2020

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TLR3 deficiency in patients with herpes simplex encephalitis

31 March 2020

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Human genetics of infectious diseases: a unified theory

31 March 2020

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31 March 2020

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Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease

31 March 2020

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Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction

31 March 2020

1 reference

Signals of recent positive selection in a worldwide sample of human populations

31 March 2020

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Revealing the architecture of gene regulation: the promise of eQTL studies

31 March 2020

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Modifier effects between regulatory and protein-coding variation

31 March 2020

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Population genomics of human gene expression

31 March 2020

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Gene expression levels are a target of recent natural selection in the human genome

31 March 2020

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Common regulatory variation impacts gene expression in a cell type-dependent manner

31 March 2020

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A genome-wide in vitro bacterial-infection screen reveals human variation in the host response associated with inflammatory disease

31 March 2020

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Innate immune recognition

31 March 2020

1 reference

Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

31 March 2020

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Toll-like receptors and innate immunity

31 March 2020

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Toll-like receptors--taking an evolutionary approach

31 March 2020

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Innate immune recognition of viral infection

31 March 2020

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Self- and nonself-recognition by C-type lectins on dendritic cells

31 March 2020

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Nod-like proteins in immunity, inflammation and disease

31 March 2020

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Recognition of viruses by innate immunity.

31 March 2020

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Autoreactivity by design: innate B and T lymphocytes

31 March 2020

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Discovering the role of the major histocompatibility complex in the immune response

31 March 2020

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Fundamental concepts in genetics: Genetics and the understanding of selection

31 March 2020

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Molecular signatures of natural selection

31 March 2020

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Methods to detect selection in populations with applications to the human

31 March 2020

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High genomic deleterious mutation rates in hominids

31 March 2020

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Most rare missense alleles are deleterious in humans: implications for complex disease and association studies

31 March 2020

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The signature of positive selection on standing genetic variation

31 March 2020

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Balancing selection and its effects on sequences in nearby genome regions

31 March 2020

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Adaptive protein evolution at the Adh locus in Drosophila

31 March 2020

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Statistical methods for detecting molecular adaptation

31 March 2020

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Control of the False Discovery Rate Applied to the Detection of Positively Selected Amino Acid Sites

31 March 2020

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Progress and prospects in mapping recent selection in the genome.

31 March 2020

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Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems

31 March 2020

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KIR: diverse, rapidly evolving receptors of innate and adaptive immunity

31 March 2020

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Understanding how combinations of HLA and KIR genes influence disease

31 March 2020

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Unusual selection on the KIR3DL1/S1 natural killer cell receptor in africans

31 March 2020

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Hemoglobin E: a balanced polymorphism protective against high parasitemias and thus severe P falciparum malaria

31 March 2020

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12 December 2020

Polymorphism and balancing selection at major histocompatibility complex loci

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12 December 2020

Transcription factor PRDII-BF1 activates human immunodeficiency virus type 1 gene expression

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12 December 2020

Nucleotide variability at G6pd and the signature of malarial selection in humans.

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12 December 2020

Likelihood models for detecting positively selected amino acid sites and applications to the HIV-1 envelope gene

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12 December 2020

Hemoglobin C associated with protection from severe malaria in the Dogon of Mali, a West African population with a low prevalence of hemoglobin S.

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12 December 2020

Excess of rare amino acid polymorphisms in the Toll-like receptor 4 in humans

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12 December 2020

Identifiers

DOI

10.1038/NRG2698

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Dimensions Publication ID

21 August 2017

1001355162

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