(Q37650990)

21 August 2017

1 reference

20 December 2019

Paxillin: a crossroad in pathological cell migration (English)

1 reference

21 August 2017

1 reference

4 August 2019

1 reference

Ana María López-Colomé

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28214467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Irene Lee-Rivera

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28214467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Regina Benavides-Hidalgo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28214467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Edith López

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28214467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

publication date

18 February 2017

6 references

Journal of Hematology & Oncology

21 August 2017

4 August 2019

20 November 2019

28 November 2019

15 December 2019

20 December 2019

6 references

4 August 2019

20 November 2019

28 November 2019

15 December 2019

20 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28214467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28214467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28214467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28214467%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

13 June 2020

copyright license

5 references

4 August 2019

20 November 2019

28 November 2019

15 December 2019

https://scigraph.springernature.com/pub.10.1186/s13045-017-0418-y

20 December 2019

0 references

0 references

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Phosphatase and Tensin Homolog (PTEN) Represses Colon Cancer Progression through Inhibiting Paxillin Transcription via PI3K/AKT/NF-κB Pathway

23 August 2017

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c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injury

23 August 2017

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23 August 2017

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23 August 2017

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Paxillin inhibits HDAC6 to regulate microtubule acetylation, Golgi structure, and polarized migration

23 August 2017

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23 August 2017

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Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway

23 August 2017

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Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells

23 August 2017

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Phagocytic receptors activate and immune inhibitory receptor SIRPα inhibits phagocytosis through paxillin and cofilin

23 August 2017

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Altering FAK-paxillin interactions reduces adhesion, migration and invasion processes

23 August 2017

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Mitogen-activated protein kinase (MAPK) pathway regulates branching by remodeling epithelial cell adhesion

23 August 2017

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Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression

23 August 2017

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A central role for vimentin in regulating repair function during healing of the lens epithelium

23 August 2017

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Ganoderiol A-enriched extract suppresses migration and adhesion of MDA-MB-231 cells by inhibiting FAK-SRC-paxillin cascade pathway

23 August 2017

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23 August 2017

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Paxillin phosphorylation counteracts proteoglycan-mediated inhibition of axon regeneration

23 August 2017

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cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: effects of PKA and EPAC.

23 August 2017

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Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice

23 August 2017

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Diverse roles for the paxillin family of proteins in cancer

23 August 2017

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The phosphatase PTP-PEST/PTPN12 regulates endothelial cell migration and adhesion, but not permeability, and controls vascular development and embryonic viability

23 August 2017

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Paxillin regulates pulmonary arterial smooth muscle cell function in pulmonary hypertension

23 August 2017

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CdGAP regulates cell migration and adhesion dynamics in two-and three-dimensional matrix environments

23 August 2017

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Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA

23 August 2017

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Paxillin phosphorylation and complexing with Erk and FAK are regulated by PLD activity in MDA-MB-231 cells

23 August 2017

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Central role of paxillin phosphorylation in regulation of LFA-1 integrins activity and lymphocyte migration

23 August 2017

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Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning

23 August 2017

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Paxillin enables attachment-independent tyrosine phosphorylation of focal adhesion kinase and transformation by RAS.

23 August 2017

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Calpain-mediated proteolysis of paxillin negatively regulates focal adhesion dynamics and cell migration

23 August 2017

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23 August 2017

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Cytohesin-2/ARNO, through its interaction with focal adhesion adaptor protein paxillin, regulates preadipocyte migration via the downstream activation of Arf6.

23 August 2017

1 reference

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Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

23 August 2017

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The NCBI BioSystems database

23 August 2017

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JNK phosphorylates beta-catenin and regulates adherens junctions

23 August 2017

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Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion

23 August 2017

1 reference

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Cross talk between paxillin and Rac is critical for mediation of barrier-protective effects by oxidized phospholipids

23 August 2017

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23 August 2017

Paxillin comes of age

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Insulin-like Growth Factors as Regulators of Cell Motility Signaling Mechanisms

23 August 2017

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Paxillin-dependent stimulation of microtubule catastrophes at focal adhesion sites

23 August 2017

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Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion

23 August 2017

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Cdk5 regulates differentiation of oligodendrocyte precursor cells through the direct phosphorylation of paxillin

23 August 2017

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GEFs and GAPs: critical elements in the control of small G proteins

23 August 2017

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Focal adhesion kinase and paxillin: novel regulators of brain sexual differentiation?

23 August 2017

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Serine phosphorylation regulates paxillin turnover during cell migration

23 August 2017

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Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics

23 August 2017

1 reference

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Oncomirs - microRNAs with a role in cancer

23 August 2017

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MicroRNA function: multiple mechanisms for a tiny RNA?

23 August 2017

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Paxillin phosphorylation sites mapped by mass spectrometry

23 August 2017

1 reference

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Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness

23 August 2017

1 reference

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Regulation of Rho and Rac signaling to the actin cytoskeleton by paxillin during Drosophila development

23 August 2017

1 reference

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Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility.

23 August 2017

1 reference

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Phosphorylation of paxillin by p38MAPK is involved in the neurite extension of PC-12 cells

23 August 2017

1 reference

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FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

23 August 2017

1 reference

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Cell migration: Rho GTPases lead the way

23 August 2017

1 reference

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Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis

23 August 2017

1 reference

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Differential regulation of cell motility and invasion by FAK

23 August 2017

1 reference

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The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling

23 August 2017

1 reference

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Molecular dissection of actopaxin-integrin-linked kinase-Paxillin interactions and their role in subcellular localization

23 August 2017

1 reference

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Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells

23 August 2017

1 reference

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Paxillin and focal adhesion signalling

23 August 2017

1 reference

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Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeleton

23 August 2017

1 reference

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Role of the cytoskeletal protein paxillin in oncogenesis

23 August 2017

1 reference

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Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding

23 August 2017

1 reference

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Characterisation of the paxillin-binding site and the C-terminal focal adhesion targeting sequence in vinculin

23 August 2017

1 reference

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Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase

23 August 2017

1 reference

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pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

23 August 2017

1 reference

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Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Paxillin is a major phosphotyrosine-containing protein during embryonic development

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Overexpression of Paxillin Correlates with Tumor Progression and Predicts Poor Survival in Glioblastoma.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Regulating Rho GTPases and their regulators

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

MicroRNA-145 suppresses cell migration and invasion by targeting paxillin in human colorectal cancer cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Intracellular signaling and perception of neuronal scaffold through integrins and their adapter proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

The integrin adhesome: from genes and proteins to human disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

miR-137 impairs the proliferative and migratory capacity of human non-small cell lung cancer cells by targeting paxillin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

MLK3 regulates paxillin phosphorylation in chemokine-mediated breast cancer cell migration and invasion to drive metastasis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Paxillin predicts survival and relapse in non-small cell lung cancer by microRNA-218 targeting

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Nemo-like kinase is involved in NGF-induced neurite outgrowth via phosphorylating MAP1B and paxillin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Paxillin nuclear-cytoplasmic localization is regulated by phosphorylation of the LD4 motif: evidence that nuclear paxillin promotes cell proliferation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

CdGAP associates with actopaxin to regulate integrin-dependent changes in cell morphology and motility

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Localized stabilization of microtubules by integrin- and FAK-facilitated Rho signaling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Expression patterns of focal adhesion associated proteins in the developing retina

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Tyrosine phosphorylation and enhanced expression of paxillin during neuronal differentiation in vitro

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Focal adhesion kinases in adhesion structures and disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Glycogen synthase kinase 3- and extracellular signal-regulated kinase-dependent phosphorylation of paxillin regulates cytoskeletal rearrangement

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Ras-induced serine phosphorylation of the focal adhesion protein paxillin is mediated by the Raf-->MEK-->ERK pathway

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Calyculin-A induces focal adhesion assembly and tyrosine phosphorylation of p125(Fak), p130(Cas), and paxillin in Swiss 3T3 cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Paxillin isoforms in mouse. Lack of the gamma isoform and developmentally specific beta isoform expression.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Retinoic acid induces nuclear FAK translocation and reduces breast cancer cell adhesion through Moesin, FAK, and Paxillin.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Paxillin, a novel controller in the signaling of estrogen to FAK/N-WASP/Arp2/3 complex in breast cancer cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

PKCε-mediated c-Met endosomal processing directs fluctuant c-Met-JNK-paxillin signaling for tumor progression of HepG2.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Concerted modulation of paxillin dynamics at focal adhesions by Deleted in Liver Cancer-1 and focal adhesion kinase during early cell spreading.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Endothelial paxillin and focal adhesion kinase (FAK) play a critical role in neutrophil transmigration.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Paxillin associates with the microtubule cytoskeleton and the immunological synapse of CTL through its leucine-aspartic acid domains and contributes to microtubule organizing center reorientation.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Hypophosphorylated and inactive Pyk2 associates with paxillin at the microtubule organizing center in hematopoietic cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Role of formation of an ERK-FAK-paxillin complex in migration of human corneal epithelial cells during wound closure in vitro.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Cortical deficiency of laminin gamma1 impairs the AKT/GSK-3beta signaling pathway and leads to defects in neurite outgrowth and neuronal migration.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

The expression of the cytoskeletal focal adhesion protein paxillin in breast cancer correlates with HER2 overexpression and may help predict response to chemotherapy: a retrospective immunohistochemical study

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

A paxillin tyrosine phosphorylation switch regulates the assembly and form of cell-matrix adhesions.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Regulation of paxillin family members during epithelial-mesenchymal transformation: a putative role for paxillin delta.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Sequential activation of RhoA and FAK/paxillin leads to ATP release and actin reorganization in human endothelium

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Paxillin binding to the alpha 4 integrin subunit stimulates LFA-1 (integrin alpha L beta 2)-dependent T cell migration by augmenting the activation of focal adhesion kinase/proline-rich tyrosine kinase-2.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Regulation of focal complex composition and disassembly by the calcium-dependent protease calpain.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Roles for the tubulin- and PTP-PEST-binding paxillin LIM domains in cell adhesion and motility

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5316197

Reactive oxygen species activate focal adhesion kinase, paxillin and p130cas tyrosine phosphorylation in endothelial cells

1 September 2018

1 reference

12 December 2020

Paxillin is the target of c-Jun N-terminal kinase in Schwann cells and regulates migration

1 reference

12 December 2020

Phosphorylation of paxillin via the ERK mitogen-activated protein kinase cascade in EL4 thymoma cells

1 reference

12 December 2020

The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase

1 reference

12 December 2020

10.1186/S13045-017-0418-Y

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28214467%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28214467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference