(Q36539304)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Benjamin Stutchbury

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Guillaume Jacquemet

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Christoph Ballestrem

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

author name string

Jonathan D Humphries

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Simon T Barry

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Martin J Humphries

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

language of work or name

English

0 references

publication date

1 February 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

published in

Journal of Cell Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

volume

212

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

page(s)

349-364

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

6 March 2020

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

based on heuristic

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4739608/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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FAK dimerization controls its kinase-dependent functions at focal adhesions

30 September 2017

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Distinct FAK activities determine progenitor and mammary stem cell characteristics

30 September 2017

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β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

30 September 2017

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Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Inhibition of focal adhesion kinase by PF-562,271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment

30 September 2017

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30 September 2017

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Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

30 September 2017

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Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins

30 September 2017

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30 September 2017

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Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

30 September 2017

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PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.

30 September 2017

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Regulation of adhesion dynamics by calpain-mediated proteolysis of focal adhesion kinase (FAK).

30 September 2017

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Src kinases as therapeutic targets for cancer

30 September 2017

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Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6

30 September 2017

1 reference

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Combined integrin phosphoproteomic analyses and small interfering RNA--based functional screening identify key regulators for cancer cell adhesion and migration

30 September 2017

1 reference

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Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner

30 September 2017

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MatrixDB, a database focused on extracellular protein-protein and protein-carbohydrate interactions

30 September 2017

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Src and focal adhesion kinase as therapeutic targets in cancer

30 September 2017

1 reference

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Vinculin controls focal adhesion formation by direct interactions with talin and actin.

30 September 2017

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Synergistic control of cell adhesion by integrins and syndecans.

30 September 2017

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Integration of biological networks and gene expression data using Cytoscape

30 September 2017

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Functional atlas of the integrin adhesome

30 September 2017

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Forces and bond dynamics in cell adhesion.

30 September 2017

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Cellular characterization of a novel focal adhesion kinase inhibitor

30 September 2017

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Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics

30 September 2017

1 reference

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Identification of potential biomarkers for measuring inhibition of Src kinase activity in colon cancer cells following treatment with dasatinib

30 September 2017

1 reference

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N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Expression of FAK-related non-kinase (FRNK) coincides with morphological change in the early stage of cell adhesion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Integrin-regulated FAK-Src signaling in normal and cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Molecular mapping of tyrosine-phosphorylated proteins in focal adhesions using fluorescence resonance energy transfer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

The integrin-actin connection, an eternal love affair

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption.

30 September 2017

1 reference

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The specificities of protein kinase inhibitors: an update

30 September 2017

1 reference

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Signal transduction by cell adhesion receptors and the cytoskeleton: functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members

30 September 2017

1 reference

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Focal adhesion kinase is involved in mechanosensing during fibroblast migration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Specificity and mechanism of action of some commonly used protein kinase inhibitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

FAK integrates growth-factor and integrin signals to promote cell migration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Probability-based protein identification by searching sequence databases using mass spectrometry data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Regulation of leukocyte adhesion and signaling in inflammation and disease.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Adhesion signalling complexes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Focal adhesion kinase-dependent regulation of adhesive forces involves vinculin recruitment to focal adhesions

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Involvement of microtubules in the control of adhesion-dependent signal transduction.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Integrated network analysis platform for protein-protein interactions

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Y-27632, an inhibitor of rho-associated protein kinase, suppresses tumor cell invasion via regulation of focal adhesion and focal adhesion kinase.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4739608

Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26833789

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.201508080

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26833789%20AND%20SRC:MED&resulttype=core&format=json