(Q37669790)

21 August 2017

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title

T helper 17 cells: discovery, function, and physiological trigger (English)

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21 August 2017

author name string

Miriam Beer Torchinsky

series ordinal

1

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21 August 2017

J Magarian Blander

series ordinal

2

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21 August 2017

language of work or name

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7 January 2010

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Cellular and Molecular Life Sciences

21 August 2017

published in

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21 August 2017

volume

67

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21 August 2017

issue

9

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21 August 2017

page(s)

1407-1421

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https://scigraph.springernature.com/pub.10.1007/s00018-009-0248-3

21 August 2017

exact match

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cites work

Microbial lipopeptides induce the production of IL-17 in Th cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0248-3

CD4+ T cells mediate abscess formation in intra-abdominal sepsis by an IL-17-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0248-3

IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0248-3

Cutting edge: immune cells as sources and targets of the IL-10 family members?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0248-3

T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0248-3

Transplantation survival is maintained by granzyme B+ regulatory cells and adaptive regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0248-3

Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0248-3

Interleukin-17 and lung host defense against Klebsiella pneumoniae infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0248-3

Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0248-3

IL-17A produced by gammadelta T cells plays a critical role in innate immunity against listeria monocytogenes infection in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0248-3

A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

21 January 2018

1 reference

12 December 2020

Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells

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12 December 2020

Cytokine signaling modules in inflammatory responses

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12 December 2020

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

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12 December 2020

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

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12 December 2020

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

1 reference

12 December 2020

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

1 reference

12 December 2020

Intracytosolic Listeria monocytogenes induces cell death through caspase-1 activation in murine macrophages

1 reference

12 December 2020

T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation

1 reference

12 December 2020

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

1 reference

12 December 2020

Phenotypic and functional features of human Th17 cells

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12 December 2020

Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1

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12 December 2020

Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

1 reference

12 December 2020

Neuropilin-1 expression on regulatory T cells enhances their interactions with dendritic cells during antigen recognition

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12 December 2020

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

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12 December 2020

Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense

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12 December 2020

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

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12 December 2020

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12 December 2020

Neuropilin-1: a surface marker of regulatory T cells

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12 December 2020

Lineage commitment in the immune system: the T helper lymphocyte grows up.

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12 December 2020

Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

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12 December 2020

IL-17A is produced by Th17, gammadelta T cells and other CD4- lymphocytes during infection with Salmonella enterica serovar Enteritidis and has a mild effect in bacterial clearance

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12 December 2020

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

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12 December 2020

The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

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12 December 2020

The different faces of Notch in T-helper-cell differentiation

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12 December 2020

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

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12 December 2020

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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12 December 2020

Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression

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12 December 2020

IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation

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12 December 2020

Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction

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12 December 2020

A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma

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12 December 2020

STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

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12 December 2020

Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation

1 reference

12 December 2020

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

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12 December 2020

Interferon-gamma confers resistance to experimental allergic encephalomyelitis.

1 reference

12 December 2020

How microorganisms tip the balance between interleukin-12 family members

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12 December 2020

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

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12 December 2020

Toll-dependent selection of microbial antigens for presentation by dendritic cells

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12 December 2020

T cell regulation as a side effect of homeostasis and competition

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12 December 2020

Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

1 reference

12 December 2020

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

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12 December 2020

Differential effect of IL-27 on developing versus committed Th17 cells.

1 reference

12 December 2020

An IL-17F/A heterodimer protein is produced by mouse Th17 cells and induces airway neutrophil recruitment

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12 December 2020

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

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12 December 2020

Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin-17 receptor IgG1 Fc fusion protein

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12 December 2020

TGF-beta-induced Foxp3+ regulatory T cells rescue scurfy mice

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12 December 2020

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

1 reference

12 December 2020

The AP-1 transcription factor Batf controls T(H)17 differentiation

1 reference

12 December 2020

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

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12 December 2020

The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4

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12 December 2020

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells

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12 December 2020

IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis

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12 December 2020

Immunosuppressive effects of apoptotic cells

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12 December 2020

The critical role of IL-12 and the IL-12R beta 2 subunit in the generation of pathogenic autoreactive Th1 cells.

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12 December 2020

Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice

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12 December 2020

Regulation of the IL-12/IL-12R axis: a critical step in T-helper cell differentiation and effector function

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12 December 2020

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

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12 December 2020

Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes.

1 reference

12 December 2020

IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination

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12 December 2020

Host susceptibility to the attaching and effacing bacterial pathogen Citrobacter rodentium

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12 December 2020

A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3.

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12 December 2020

Recognition of microorganisms and activation of the immune response

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12 December 2020

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.

1 reference

12 December 2020

CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes

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12 December 2020

Regulation of inflammatory responses by IL-17F

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12 December 2020

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

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12 December 2020

TL1A-DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease

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12 December 2020

CTLA-4 control over Foxp3+ regulatory T cell function

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12 December 2020

Infectious immunological tolerance

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12 December 2020

Th memory for interleukin-17 expression is stable in vivo.

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12 December 2020

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

1 reference

12 December 2020

TH17 cells in development: an updated view of their molecular identity and genetic programming

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12 December 2020

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

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12 December 2020

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

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12 December 2020

Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection

1 reference

12 December 2020

DC activated via dectin-1 convert Treg into IL-17 producers

1 reference

12 December 2020

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

1 reference

12 December 2020

Characterization of murine BATF: a negative regulator of activator protein-1 activity in the thymus.

1 reference

12 December 2020

CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion

1 reference

12 December 2020

Development, cytokine profile and function of human interleukin 17-producing helper T cells

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12 December 2020

Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation

1 reference

12 December 2020

Bacteroides fragilis enterotoxin induces the expression of IL-8 and transforming growth factor-beta (TGF-beta) by human colonic epithelial cells

1 reference

12 December 2020

Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice

1 reference

12 December 2020

Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease

1 reference

12 December 2020

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

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12 December 2020

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

1 reference

12 December 2020

Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells.

1 reference

12 December 2020

Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model.

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12 December 2020

IL-21 and TGF-beta are required for differentiation of human T(H)17 cells

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12 December 2020

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

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12 December 2020

Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells

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12 December 2020

Negative regulation of Th17 responses

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12 December 2020

Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice

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12 December 2020

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

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12 December 2020

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

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12 December 2020

IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner

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12 December 2020

Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae

1 reference

12 December 2020

IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis

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12 December 2020

Late developmental plasticity in the T helper 17 lineage

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12 December 2020

IL-23-dependent IL-17 production is essential in neutrophil recruitment and activity in mouse lung defense against respiratory Mycoplasma pneumoniae infection

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12 December 2020

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

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12 December 2020

Increased expression of interleukin 17 in inflammatory bowel disease

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12 December 2020

Transforming growth factor-beta induces development of the T(H)17 lineage

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12 December 2020

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

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12 December 2020

Critical role of IL-17 receptor signaling in acute TNBS-induced colitis

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12 December 2020

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

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12 December 2020

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

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12 December 2020

Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo

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12 December 2020

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

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12 December 2020

Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

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12 December 2020

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

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12 December 2020

How are T(H)1 and T(H)2 effector cells made?

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12 December 2020

Functional diversity of helper T lymphocytes

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12 December 2020

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

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12 December 2020

Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells.

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12 December 2020

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

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12 December 2020

Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis

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12 December 2020

Innate immune recognition of infected apoptotic cells directs T(H)17 cell differentiation.

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12 December 2020

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

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12 December 2020

Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces

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12 December 2020

Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice

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12 December 2020

Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

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12 December 2020

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

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12 December 2020

Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo

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12 December 2020

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells

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12 December 2020

Hepatocellular apoptosis during Candida albicans colonization: involvement of TNF-alpha and infiltrating Fas-L positive lymphocytes

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12 December 2020

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

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12 December 2020

Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta

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12 December 2020

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

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12 December 2020

The search for endogenous activators of the aryl hydrocarbon receptor

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12 December 2020

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

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12 December 2020

Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection.

1 reference

12 December 2020

The biological functions of T helper 17 cell effector cytokines in inflammation

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12 December 2020

10.1007/S00018-009-0248-3

Identifiers

DOI

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21 August 2017

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