(Q37671776)

English

DHA derivatives of fish oil as dietary supplements: a nutrition-based drug discovery approach for therapies to prevent metabolic cardiotoxicity

scientific article published on 24 June 2012

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scholarly article

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Europe PubMed Central

PMC publication ID

21 August 2017

DHA derivatives of fish oil as dietary supplements: a nutrition-based drug discovery approach for therapies to prevent metabolic cardiotoxicity (English)

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Yonggang Ma

1

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Merry L Lindsey

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Ganesh V Halade

3

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

language of work or name

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publication date

24 June 2012

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Expert Opinion on Drug Discovery

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

711-721

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Efficacy of omega-3 fatty acid supplements (eicosapentaenoic acid and docosahexaenoic acid) in the secondary prevention of cardiovascular disease: a meta-analysis of randomized, double-blind, placebo-controlled trials

1 reference

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1 reference

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Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010

1 reference

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Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events

1 reference

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Docosahexaenoic acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer's, and other neurodegenerative diseases

1 reference

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Eicosapentaenoic acid ethyl ester (AMR101) therapy in patients with very high triglyceride levels (from the Multi-center, plAcebo-controlled, Randomized, double-blINd, 12-week study with an open-label Extension [MARINE] trial).

1 reference

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Serum phospholipid fatty acids and prostate cancer risk: results from the prostate cancer prevention trial

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Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century

1 reference

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Omega-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cyclic GMP/protein kinase G signaling in cardiac fibroblasts

1 reference

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14S,21R-dihydroxydocosahexaenoic acid remedies impaired healing and mesenchymal stem cell functions in diabetic wounds

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Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice

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GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects

1 reference

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Omega-3 polyunsaturated fatty acids in the treatment of kidney disease

1 reference

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23 August 2017

Docosahexaenoic acid-enriched fish oil attenuates kidney disease and prolongs median and maximal life span of autoimmune lupus-prone mice

1 reference

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High fat diet-induced animal model of age-associated obesity and osteoporosis

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23 August 2017

Omega-3 fatty acids and cardiovascular disease risk: do we understand the relationship?

1 reference

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Omega-3 polyunsaturated fatty acids and cardiovascular diseases

1 reference

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23 August 2017

Omega-3 dietary supplements and the risk of cardiovascular events: a systematic review.

1 reference

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23 August 2017

Docosahexaenoic acid (DHA) and cardiovascular disease risk factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

23 August 2017

Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells.

1 reference

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Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies

1 reference

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23 August 2017

Fish oil supplementation improves endothelial function in normoglycemic offspring of patients with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

23 August 2017

Comparative effects of DHA and EPA on cell function.

1 reference

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23 August 2017

Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: a role for resolvins and protectins

1 reference

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23 August 2017

Docosahexaenoic acid induces dose dependent cell death in an early undifferentiated subtype of acute myeloid leukemia cell line

1 reference

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Inverse association of erythrocyte n-3 fatty acid levels with inflammatory biomarkers in patients with stable coronary artery disease: The Heart and Soul Study

1 reference

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DHA supplementation decreases serum C-reactive protein and other markers of inflammation in hypertriglyceridemic men

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

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Clinical overview of algal-docosahexaenoic acid: effects on triglyceride levels and other cardiovascular risk factors

1 reference

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Nutrient sensing and inflammation in metabolic diseases

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An emerging risk factor for obesity: does disequilibrium of polyunsaturated fatty acid metabolism contribute to excessive adipose tissue development?

1 reference

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Translating molecular discoveries into new therapies for atherosclerosis

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1 reference

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Safety considerations with omega-3 fatty acid therapy

1 reference

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ECM remodeling in hypertensive heart disease

1 reference

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Omega-3 fatty acids and hypertension in humans

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TGFbeta, cardiac fibroblasts, and the fibrotic response

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Dietary omega-3 fatty acid intake and cardiovascular risk

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Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers

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23 August 2017

The cardiac fibroblast: therapeutic target in myocardial remodeling and failure

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Role of endothelial dysfunction in atherosclerosis

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C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease

1 reference

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Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals

1 reference

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Eicosapentaenoic acid (EPA) induces Ca(2+)-independent activation and translocation of endothelial nitric oxide synthase and endothelium-dependent vasorelaxation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

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Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing

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23 August 2017

Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico

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23 August 2017

Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans

1 reference

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The pathogenesis of atherosclerosis: a perspective for the 1990s

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23 August 2017

Does fish oil lower blood pressure? A meta-analysis of controlled trials

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23 August 2017

Fish oil prevents insulin resistance induced by high-fat feeding in rats

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

23 August 2017

Similarities and differences between the effects of EPA and DHA on markers of atherosclerosis in human subjects

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6 September 2017

The differential effects of EPA and DHA on cardiovascular risk factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

6 September 2017

Resolvins E1 and D1 in choroid-retinal endothelial cells and leukocytes: biosynthesis and mechanisms of anti-inflammatory actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

14 September 2017

EPA, but not DHA, decreases mean platelet volume in normal subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

25 June 2018

Effects of highly purified eicosapentaenoic acid and docosahexaenoic acid on hemodynamics in humans.

1 reference

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Plasma lipid and lipoprotein pattern in Greenlandic West-coast Eskimos.

1 reference

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25 June 2018

Serum lipids, hepatic glycerolipid metabolism and peroxisomal fatty acid oxidation in rats fed omega-3 and omega-6 fatty acids

1 reference

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25 June 2018

Fatty acid composition of the plasma lipids in Greenland Eskimos

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Roles of saturated vs. polyunsaturated fat in heart failure survival: not all fats are created equal.

1 reference

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1 September 2018

19,20-EpDPE, a bioactive CYP450 metabolite of DHA monoacyglyceride, decreases Ca²⁺ sensitivity in human pulmonary arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

Eicosapentaenoic acid prevents atrial fibrillation associated with heart failure in a rabbit model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

Docosahexaenoic acid derivative prevents inflammation and hyperreactivity in lung: implication of PKC-Potentiated inhibitory protein for heterotrimeric myosin light chain phosphatase of 17 kD in asthma

1 reference

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1 September 2018

The beneficial effect of n-3 polyunsaturated fatty acids on doxorubicin-induced chronic heart failure in rats

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1 September 2018

n-3 Polyunsaturated fatty acids alter expression of fibrotic and hypertrophic genes in a dog model of atrial cardiomyopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

Effects of n-3 fatty acids on macro- and microvascular function in subjects with type 2 diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

Comparison of bleeding complications with omega-3 fatty acids + aspirin + clopidogrel--versus--aspirin + clopidogrel in patients with cardiovascular disease

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1 September 2018

Omega-6 Fatty Acids and Risk for Cardiovascular Disease: A Science Advisory From the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on E

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1 September 2018

Prevention and reversal of obesity and glucose intolerance in mice by DHA derivatives

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1 September 2018

Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial

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1 September 2018

Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice

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1 September 2018

Dietary n-3 polyunsaturated fatty acids and direct renin inhibition improve electrical remodeling in a model of high human renin hypertension

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1 September 2018

Low-dose docosahexaenoic acid lowers diastolic blood pressure in middle-aged men and women.

1 reference

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1 September 2018

Long-term intake of edible oils benefits blood pressure and myocardial structure in spontaneously hypertensive rat (SHR) and streptozotocin diabetic SHR.

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1 September 2018

Synthesis of docosahexaenoic acid derivatives designed as novel PPARgamma agonists and antidiabetic agents

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1 September 2018

Diacylglycerol-containing docosahexaenoic acid in acyl chain modulates airway smooth muscle tone

1 reference

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1 September 2018

Omega-3 PUFA of marine origin limit diet-induced obesity in mice by reducing cellularity of adipose tissue.

1 reference

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1 September 2018

Identification of putative metabolites of docosahexaenoic acid as potent PPARgamma agonists and antidiabetic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

Docosahexaenoic acid restores endothelial function in children with hyperlipidemia: results from the EARLY study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

Modulation of doxorubicin-induced cardiac dysfunction in toll-like receptor-2-knockout mice

1 reference

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1 September 2018

Effect of eicosapentaenoic acid and docosahexaenoic acid on oxidative stress and inflammatory markers in treated-hypertensive type 2 diabetic subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

Inhibition of tumour necrosis factor-alpha and interleukin 6 production by mononuclear cells following dietary fish-oil supplementation in healthy men and response to antioxidant co-supplementation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

Long-term treatment with eicosapentaenoic acid improves exercise-induced vasodilation in patients with coronary artery disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

Eicosapentaenoic acid improves endothelial function in hypertriglyceridemic subjects despite increased lipid oxidizability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

The n-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid increase systemic arterial compliance in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

Relationship between circulating n-3 fatty acid concentrations and endothelial function in early adulthood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL particle size, glucose, and insulin in mildly hyperlipidemic men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

Dietary supplementation with marine omega-3 fatty acids improve systemic large artery endothelial function in subjects with hypercholesterolemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

The effect on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969443

1 September 2018

Differential effects of conjugated linoleic acid isomers in insulin-resistant female C57Bl/6J mice.

1 reference

https://api.crossref.org/works/10.1517%2F17460441.2012.694862

21 January 2018

Differential effects of eicosapentaenoic acid and docosahexaenoic acid on vascular reactivity of the forearm microcirculation in hyperlipidemic, overweight men

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta function blocking prevents myocardial fibrosis and diastolic dysfunction in pressure-overloaded rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic GMP/protein kinase G phosphorylation of Smad3 blocks transforming growth factor-beta-induced nuclear Smad translocation: a key antifibrogenic mechanism of atrial natriuretic peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced ex Vivo Interleukin-6 Production by Dietary Fish Oil Is Not Modified by Linoleic Acid Intake in Healthy Men

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of hypertension treatment and control with all-cause and cardiovascular disease mortality among US adults with hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary Fish Oil Alters T Lymphocyte Cell Populations and Exacerbates Disease in a Mouse Model of Inflammatory Colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid Metabolism, Atherogenesis, and Haemostasis in Eskimos: the Role of the Prostaglandin-3 Family

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inverse relation between fish consumption and 20-year mortality from coronary heart disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary cod-liver oil improves endothelium-dependent responses in hypercholesterolemic and atherosclerotic porcine coronary arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marine oils dose-dependently inhibit vasoconstriction of forearm resistance vessels in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of different amounts of n-3 polyunsaturated fatty acids on bleeding time and in vivo vascular reactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purified eicosapentaenoic acid reduces small dense LDL, remnant lipoprotein particles, and C-reactive protein in metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1517/17460441.2012.694862

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

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