(Q37691486)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20152067%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

review article

1 reference

title

Epigenetic mechanisms regulating normal and malignant haematopoiesis: new therapeutic targets for clinical medicine (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20152067%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20152067%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

David T Bowen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20152067%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

publication date

15 February 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20152067%20AND%20SRC:MED&resulttype=core&format=json

Expert Reviews in Molecular Medicine

18 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20152067%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20152067%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

e6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20152067%20AND%20SRC:MED&resulttype=core&format=json

Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

18 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Gene silencing by DNA methylation in haematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Replication-independent chromatin loading of Dnmt1 during G2 and M phases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Induction of Tumors in Mice by Genomic Hypomethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

MiR-15a and miR-16-1 cluster functions in human leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

MicroRNAs in the ontogeny of leukemias and lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

MicroRNA control in the immune system: basic principles

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

MicroRNAs modulate hematopoietic lineage differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

The biology of Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

AML1(-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Haploinsufficiency of Runx1 results in the acceleration of mesodermal development and hemangioblast specification upon in vitro differentiation of ES cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Genetic regulatory networks programming hematopoietic stem cells and erythroid lineage specification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Runx1 is expressed in adult mouse hematopoietic stem cells and differentiating myeloid and lymphoid cells, but not in maturing erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Loss of the B-lineage-specific gene expression program in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Epigenetic silencing of the c-fms locus during B-lymphopoiesis occurs in discrete steps and is reversible.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Allosteric Inhibition of the Protein-Protein Interaction between the Leukemia-Associated Proteins Runx1 and CBFβ

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Multilineage gene expression precedes commitment in the hemopoietic system

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Polycomb silencing blocks transcription initiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

General transcription factors bind promoters repressed by Polycomb group proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

GAGA facilitates binding of Pleiohomeotic to a chromatinized Polycomb response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Role of histone H2A ubiquitination in Polycomb silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Polycomb silencing mechanisms and the management of genomic programmes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Chromatin maps, histone modifications and leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Genome-wide views of chromatin structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Chromatin modifier enzymes, the histone code and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

The epigenomics of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Gene silencing quantitatively controls the function of a developmental trans-activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Loss of MLL5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Mll has a critical role in fetal and adult hematopoietic stem cell self-renewal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Treatment of myelodysplastic syndromes with valproic acid alone or in combination with all-trans retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Cytogenetic responses in high-risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

MOZ is essential for maintenance of hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

A phase II study of 5-azacitidine for patients with primary and post-essential thrombocythemia/polycythemia vera myelofibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

5-Azacitidine has limited therapeutic activity in myelofibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Functional cooperation between HP1 and DNMT1 mediates gene silencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Genomic DNA methylation: the mark and its mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

H3K79 methylation profiles define murine and human MLL-AF4 leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

The molecular biology of mixed lineage leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Multiple copies of RUNX1: description of 14 new patients, follow-up, and a review of the literature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Amplification of AML1 on a duplicated chromosome 21 in acute lymphoblastic leukemia: a study of 20 cases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Pathogenetic significance of ecotropic viral integration site-1 in hematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Myc influences global chromatin structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

The versatile mixed lineage leukaemia gene MLL and its many associations in leukaemogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Mechanism of leukemogenesis by the inv(16) chimeric gene CBFB/PEBP2B-MHY11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Common themes in the pathogenesis of acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Multilineage transcriptional priming and determination of alternate hematopoietic cell fates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Transcription factor complex formation and chromatin fine structure alterations at the murine c-fms (CSF-1 receptor) locus during maturation of myeloid precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

A two-step, PU.1-dependent mechanism for developmentally regulated chromatin remodeling and transcription of the c-fms gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

PU.1 and pRB Interact and Cooperate To Repress GATA-1 and Block Erythroid Differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Hierarchical recruitment of polycomb group silencing complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Role of the polycomb repressive complex 2 in acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Epigenetic gene silencing in acute promyelocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Translation of the Philadelphia chromosome into therapy for CML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Chromosomal DNA demethylation specified by protein binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Developmental programming of CpG island methylation profiles in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Polycomb CBX7 promotes initiation of heritable repression of genes frequently silenced with cancer-specific DNA hypermethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Nucleosome destabilization in the epigenetic regulation of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

The Polycomb group protein EZH2 directly controls DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Chromatin modifications and their function

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Structure of the '30 nm' chromatin fibre: a key role for the linker histone

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Crystal structure of the nucleosome core particle at 2.8 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

On the use of the word 'epigenetic'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

An operational definition of epigenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Concurrent methylation of promoters from tumor associated genes predicts outcome in acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Characterization of DNA demethylation effects induced by 5-Aza-2'-deoxycytidine in patients with myelodysplastic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Trapped in action: direct visualization of DNA methyltransferase activity in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Targeting the oligomerization domain of ETO interferes with RUNX1/ETO oncogenic activity in t(8;21)-positive leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

7 January 2021

Loops, lineage, and leukemia

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

7 January 2021

Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

7 January 2021

Low-dose 5-aza-2'-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: a multicenter phase II study in elderly patients

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

7 January 2021

Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

7 January 2021

DNA methylation changes in multiple myeloma

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001377

7 January 2021

10.1017/S1462399410001377

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20152067%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference