(Q37709569)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230764%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

review article

1 reference

title

Discovery of drugs to treat cocaine dependence: behavioral and neurochemical effects of atypical dopamine transport inhibitors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230764%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

1 reference

2

Amy H Newman

1 reference

PubMed publication ID

22 August 2017

3

Jonathan L Katz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230764%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1

Gianluigi Tanda

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230764%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Amy H Newman

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230764%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

1 reference

27 November 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230764%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

published in

Advances in Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230764%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

57

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230764%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

253-289

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230764%20AND%20SRC:MED&resulttype=core&format=json

Behavioral and neurochemical effects of the dopamine transporter ligand 4-chlorobenztropine alone and in combination with cocaine in vivo

19 January 2020

cites work

1 reference

12 December 2020

Dopamine activation of endogenous cannabinoid signaling in dorsal striatum

1 reference

12 December 2020

The effects of cannabinoids on the brain

1 reference

12 December 2020

Functional-anatomical implications of the nucleus accumbens core and shell subterritories

1 reference

12 December 2020

Pharmacotherapies for treatment of cocaine abuse: preclinical aspects

1 reference

12 December 2020

Self-administration of cocaine analogs by rats.

1 reference

12 December 2020

Comparative behavioral pharmacology of cocaine and the selective dopamine uptake inhibitor RTI-113 in the squirrel monkey

1 reference

12 December 2020

Relationships among dopamine transporter affinities and cocaine-like discriminative-stimulus effects

1 reference

12 December 2020

3'- and 4'-chloro-substituted analogs of benztropine: intravenous self-administration and in vitro radioligand binding studies in rhesus monkeys.

1 reference

12 December 2020

Highly Selective Chiral N-Substituted 3α-[Bis(4‘-fluorophenyl)methoxy]tropane Analogues for the Dopamine Transporter: Synthesis and Comparative Molecular Field Analysis

1 reference

12 December 2020

The role of monoamine uptake in the discriminative stimulus effects of cocaine and related compounds

1 reference

12 December 2020

Dopamine transporter binding without cocaine-like behavioral effects: synthesis and evaluation of benztropine analogs alone and in combination with cocaine in rodents

1 reference

12 December 2020

Further studies of the reinforcing effects of benztropine analogs in rhesus monkeys

1 reference

12 December 2020

The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter

1 reference

12 December 2020

Novel tropane-based irreversible ligands for the dopamine transporter

1 reference

12 December 2020

Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

1 reference

12 December 2020

Self-administration of cocaine: scopolamine combinations by rhesus monkeys

1 reference

12 December 2020

Ventral striatal anatomy of locomotor activity induced by cocaine, D-amphetamine, dopamine and D1/D2 agonists.

1 reference

12 December 2020

Probes for the dopamine transporter: new leads toward a cocaine-abuse therapeutic--A focus on analogues of benztropine and rimcazole

1 reference

12 December 2020

Role of dopamine in drug reinforcement and addiction in humans: results from imaging studies

1 reference

12 December 2020

Behavioral effects of rimcazole analogues alone and in combination with cocaine

1 reference

12 December 2020

Sigma receptors: potential medications development target for anti-cocaine agents

1 reference

12 December 2020

Structure-activity relationship comparison of (S)-2beta-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes and (R)-2beta-substituted 3beta-(3,4-dichlorophenyl)tropanes at the dopamine transporter

1 reference

12 December 2020

Evaluation of the blood-brain barrier transport, population pharmacokinetics, and brain distribution of benztropine analogs and cocaine using in vitro and in vivo techniques

1 reference

12 December 2020

Augmentation of the behavioral effects of amphetamine by atropine

1 reference

12 December 2020

Progressive ratio as a measure of reward strength.

1 reference

12 December 2020

BEHAVIORAL EFFECTS OF INTERACTING IMIPRAMINE AND OTHER DRUGS WITH D-AMPHETAMINE, COCAINE, AND TETRABENAZINE

1 reference

12 December 2020

Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding.

1 reference

12 December 2020

In vivo interaction of cocaine with the dopamine transporter as measured by voltammetry

1 reference

12 December 2020

Effects of N-substituted analogs of benztropine: diminished cocaine-like effects in dopamine transporter ligands

1 reference

12 December 2020

Interaction between dopamine and its transporter: role of intracellular sodium ions and membrane potential

1 reference

12 December 2020

Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine.

1 reference

12 December 2020

Structure-activity relationships at monoamine transporters for a series of N-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes: comparative molecular field analysis, synthesis, and pharmacological evaluation

1 reference

12 December 2020

Differential effects of amphetamine and dopamine uptake blockers (cocaine, nomifensine) on caudate and accumbens dialysate dopamine and 3-methoxytyramine

1 reference

12 December 2020

Effects of 4'-chloro-3 alpha-(diphenylmethoxy)-tropane on mesostriatal, mesocortical, and mesolimbic dopamine transmission: comparison with effects of cocaine

1 reference

12 December 2020

Identification of a dopamine transporter ligand that blocks the stimulant effects of cocaine.

1 reference

12 December 2020

Place conditioning and locomotor effects of N-substituted, 4',4''-difluorobenztropine analogs in rats

1 reference

12 December 2020

Recognition of benztropine by the dopamine transporter (DAT) differs from that of the classical dopamine uptake inhibitors cocaine, methylphenidate, and mazindol as a function of a DAT transmembrane 1 aspartic acid residue

1 reference

12 December 2020

The role of endocannabinoid transmission in cocaine addiction

1 reference

12 December 2020

Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and benztropine analogs

1 reference

12 December 2020

Assessment of the influence of histaminergic actions on cocaine-like effects of 3alpha-diphenylmethoxytropane analogs

1 reference

12 December 2020

Medication development for addictive disorders: the state of the science

1 reference

12 December 2020

Investigation of the potential pharmacokinetic and pharmaco-dynamic drug interaction between AHN 1-055, a potent benztropine analog used for cocaine abuse, and cocaine after dosing in rats using intracerebral microdialysis

1 reference

12 December 2020

Transport, metabolism, and in vivo population pharmacokinetics of the chloro benztropine analogs, a class of compounds extensively evaluated in animal models of drug abuse

1 reference

12 December 2020

The functional impact of SLC6 transporter genetic variation

1 reference

12 December 2020

Interactions between drugs and occupied receptors

1 reference

12 December 2020

Benztropine pretreatment does not affect responses to acute cocaine administration in human volunteers

1 reference

12 December 2020

Self-administration of cocaine-antihistamine combinations: super-additive reinforcing effects

1 reference

12 December 2020

The dopamine hypothesis of the reinforcing properties of cocaine

1 reference

12 December 2020

Localization of cocaine analog [125I]RTI 82 irreversible binding to transmembrane domain 6 of the dopamine transporter

1 reference

12 December 2020

Effects of muscarinic M1 receptor blockade on cocaine-induced elevations of brain dopamine levels and locomotor behavior in rats

1 reference

12 December 2020

Differential effects of sigma1 receptor blockade on self-administration and conditioned reinstatement motivated by cocaine vs natural reward

1 reference

12 December 2020

Neurobiology of cocaine addiction: implications for new pharmacotherapy

1 reference

12 December 2020

Applicability of the dopamine and rate hypotheses in explaining the differences in behavioral pharmacology of the chloro-benztropine analogs: studies conducted using intracerebral microdialysis and population pharmacodynamic modeling

1 reference

12 December 2020

Muscarinic preferential M(1) receptor antagonists enhance the discriminative-stimulus effects of cocaine in rats

1 reference

12 December 2020

The role of dopamine for the pathophysiology of schizophrenia

1 reference

12 December 2020

Dopamine transport inhibitors based on GBR12909 and benztropine as potential medications to treat cocaine addiction

1 reference

12 December 2020

Modulation of the endocannabinoid system: therapeutic potential against cocaine dependence

1 reference

12 December 2020

Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors

1 reference

12 December 2020

Labeling of dopamine transporter transmembrane domain 1 with the tropane ligand N-[4-(4-azido-3-[125I]iodophenyl)butyl]-2beta-carbomethoxy-3beta-(4-chlorophenyl)tropane implicates proximity of cocaine and substrate active sites

1 reference

12 December 2020

Nicotine replacement therapy for smoking cessation

1 reference

12 December 2020

Cocaine-like neurochemical effects of antihistaminic medications.

1 reference

12 December 2020

The neurobiology of cocaine addiction

1 reference

12 December 2020

The binding sites for cocaine and dopamine in the dopamine transporter overlap

1 reference

12 December 2020

Depression, anhedonia, and psychomotor symptoms: the role of dopaminergic neurocircuitry

1 reference

12 December 2020

Neurobiological basis of serotonin-dopamine antagonists in the treatment of Gilles de la Tourette syndrome

1 reference

12 December 2020

Super-additive interaction of the reinforcing effects of cocaine and H1-antihistamines in rhesus monkeys

1 reference

12 December 2020

Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil

1 reference

12 December 2020

Positive allosteric modulation of the human cannabinoid (CB) receptor by RTI-371, a selective inhibitor of the dopamine transporter

1 reference

12 December 2020

Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: comparisons with monoamine uptake inhibitors

1 reference

12 December 2020

Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment

1 reference

12 December 2020

Combinations of cocaine with other dopamine uptake inhibitors: assessment of additivity

1 reference

12 December 2020

1 reference

12 December 2020

Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence

1 reference

12 December 2020

The dopamine uptake inhibitor 3 alpha-[bis(4'-fluorophenyl)metoxy]-tropane reduces cocaine-induced early-gene expression, locomotor activity, and conditioned reward.

1 reference

12 December 2020

Psychomotor stimulant effects of the stereoisomers of chlorpheniramine.

1 reference

12 December 2020

A dopamine transport inhibitor with markedly low abuse liability suppresses cocaine self-administration in the rat.

1 reference

12 December 2020

Pharmacological characterization of the discriminative stimulus effects of cocaine in rhesus monkeys.

1 reference

12 December 2020

Effects of cocaine and related drugs in nonhuman primates. III. Self-administration by squirrel monkeys

1 reference

12 December 2020

Cocaine binding sites related to drug self-administration

1 reference

12 December 2020

Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells

1 reference

12 December 2020

Cocaine receptors on dopamine transporters are related to self-administration of cocaine

1 reference

12 December 2020

Some behavioral effects of histamine H1 antagonists in squirrel monkeys.

1 reference

12 December 2020

Neurobehavioral pharmacology of cocaine.

1 reference

12 December 2020

Evaluation of the role of norepinephrine in the reinforcing effects of psychomotor stimulants in rhesus monkeys.

1 reference

12 December 2020

Discriminative stimulus properties of cocaine: Neuropharmacological characteristics as derived from stimulus generalization experiments

1 reference

12 December 2020

Fixed-interval schedule of cocaine reinforcement: effect of dose and infusion duration

1 reference

12 December 2020

The effects of stimulants and depressants on cocaine self-administration behavior in the rhesus monkey

1 reference

12 December 2020

Effects of histamine and histamine antagonists on the uptake and release of catecholamines and 5-HT in brain synaptosomes

1 reference

12 December 2020

Novel 4'-substituted and 4',4"-disubstituted 3 alpha-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors

1 reference

12 December 2020

Differential relationships among dopamine transporter affinities and stimulant potencies of various uptake inhibitors.

1 reference

12 December 2020

Novel 3 alpha-(diphenylmethoxy)tropane analogs: potent dopamine uptake inhibitors without cocaine-like behavioral profiles.

1 reference

12 December 2020

The effects of delay of reinforcement and dose on the self-administration of cocaine and procaine in rhesus monkeys

1 reference

12 December 2020

Serotonergic modulation of the behavioral effects of cocaine in the squirrel monkey.

1 reference

12 December 2020

Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens

1 reference

12 December 2020

Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs

1 reference

12 December 2020

Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanism

1 reference

12 December 2020

Mediation of the discriminative stimulus properties of cocaine by mesocorticolimbic dopamine systems.

1 reference

12 December 2020

Benztropine abuse and overdose--case report and review

1 reference

12 December 2020

Contribution of blockade of the noradrenaline carrier to the increase of extracellular dopamine in the rat prefrontal cortex by amphetamine and cocaine

1 reference

12 December 2020

Novel N-substituted 3 alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues: selective ligands for the dopamine transporter

1 reference

12 December 2020

Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter.

1 reference

12 December 2020

Novel 3alpha-diphenylmethoxytropane analogs: selective dopamine uptake inhibitors with behavioral effects distinct from those of cocaine.

1 reference

12 December 2020

Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues

1 reference

12 December 2020

Differential binding of tropane-based photoaffinity ligands on the dopamine transporter.

1 reference

12 December 2020

Role of the dopamine transporter in the action of psychostimulants, nicotine, and other drugs of abuse

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2957007-4

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1016/S1054-3589(08)57007-4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230764%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20230764%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

20230764

1 reference