(Q37715064)

22 August 2017

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title

Regulation of angiogenesis by a small GTPase Rap1. (English)

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Magdalena Chrzanowska-Wodnicka

22 August 2017

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object named as

Magdalena Chrzanowska-Wodnicka

series ordinal

1

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publication date

16 March 2010

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22 August 2017

published in

Vascular Pharmacology

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22 August 2017

volume

53

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22 August 2017

issue

1-2

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22 August 2017

page(s)

1-10

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p130Cas Couples the tyrosine kinase Bmx/Etk with regulation of the actin cytoskeleton and cell migration

22 August 2017

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7 January 2021

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Natural history of the cavernous angioma

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Mutations in the gene encoding KRIT1, a Krev-1/rap1a binding protein, cause cerebral cavernous malformations (CCM1)

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MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion

7 January 2021

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Role of Epac1, an exchange factor for Rap GTPases, in endothelial microtubule dynamics and barrier function

7 January 2021

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Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22

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Junctional adhesion molecule A interacts with Afadin and PDZ-GEF2 to activate Rap1A, regulate beta1 integrin levels, and enhance cell migration

7 January 2021

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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

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Focal adhesion kinase, Rap1, and transcriptional induction of vascular endothelial growth factor

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How do microtubules guide migrating cells?

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Rac regulates vascular endothelial growth factor stimulated motility

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Cooperation between integrin alphavbeta3 and VEGFR2 in angiogenesis

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Bmx is a downstream Rap1 effector in VEGF-induced endothelial cell activation

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Nck and Crk mediate distinct VEGF-induced signaling pathways that serve overlapping functions in focal adhesion turnover and integrin activation

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Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis

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VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells

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Beta1 integrin expression on endothelial cells is required for angiogenesis but not for vasculogenesis.

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Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis

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Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation

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Defective vascular morphogenesis and mid-gestation embryonic death in mice lacking RA-GEF-1

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Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis

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Cooperation between VEGF and beta3 integrin during cardiac vascular development

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Ccm1 is required for arterial morphogenesis: implications for the etiology of human cavernous malformations.

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Rap1 GTPase inhibits leukocyte transmigration by promoting endothelial barrier function

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Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions

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Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family

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KRIT1 association with the integrin-binding protein ICAP-1: a new direction in the elucidation of cerebral cavernous malformations (CCM1) pathogenesis

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Interaction between krit1 and icap1alpha infers perturbation of integrin beta1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation

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Krit1 modulates beta 1-integrin-mediated endothelial cell proliferation

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The thin prep rat aortic ring assay: a modified method for the characterization of angiogenesis in whole mounts

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10.1016/J.VPH.2010.03.003

7 January 2021

Identifiers

DOI

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22 August 2017

1 reference