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Huntington's disease: pathogenesis to animal models.
scientific article published on January 2010
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scholarly article
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stated in
Europe PubMed Central
PubMed publication ID
20360611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
Huntington's disease: pathogenesis to animal models
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20360611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
main subject
pathogenesis
0 references
Huntington's disease
0 references
author name string
Puneet Kumar
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20360611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
Harikesh Kalonia
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20360611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
Anil Kumar
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20360611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360611%20AND%20SRC:MED&resulttype=core&format=json
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29 January 2020
publication date
1 January 2010
1 reference
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Europe PubMed Central
PubMed publication ID
20360611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
published in
Pharmacological Reports
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20360611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
volume
62
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20360611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20360611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
page(s)
1-14
1 reference
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Europe PubMed Central
PubMed publication ID
20360611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
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Mitochondrial DNA damage is a hallmark of chemically induced and the R6/2 transgenic model of Huntington's disease
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Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease
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Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant.
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Chronic quinolinic acid lesions in rats closely resemble Huntington's disease
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Experimental therapeutics in transgenic mouse models of Huntington's disease
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The Endocannabinoid System and Huntingtons Disease
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Ca2+ signals and death programmes in neurons
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Topological analysis of striatal lesions induced by 3-nitropropionic acid in the Lewis rat.
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Dopamine excites fast-spiking interneurons in the striatum
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Clinical correlates of dementia and disability in Huntington's disease.
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Replicating Huntington's disease phenotype in experimental animals
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Mitochondria and Huntington's disease pathogenesis: insight from genetic and chemical models
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Oxidative stress in Huntington's disease
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Clinical assessment of irritability, aggression, and apathy in Huntington and Alzheimer disease
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Role of dopamine in Huntington's disease
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Huntington's dementia. Clinical and neuropsychological features
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Psychiatric syndromes in Huntington's disease
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Endogenous GABA mediates presynaptic inhibition of spontaneous and evoked excitatory synaptic potentials in the rat neostriatum.
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Receptor subtypes involved in the presynaptic and postsynaptic actions of dopamine on striatal interneurons
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Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene
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Pre- and postsynaptic localization of GABA(B) receptors in the basal ganglia in monkeys
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CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model.
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Language changes after neurosurgery for Parkinsonism
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Socio-psychiatric consequences of Huntington's disease
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Neuro-psychiatric aspects of Huntington's disease
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Excitotoxic injury of the neostriatum: a model for Huntington's disease
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Expression of the Huntingtin-associated protein 1 gene in the developing and adult mouse.
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Inactivation of the mouse Huntington's disease gene homolog Hdh
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The distribution of GABAA-benzodiazepine receptors in the basal ganglia in Huntington's disease and in the quinolinic acid-lesioned rat.
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Selective sparing of a class of striatal neurons in Huntington's disease
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Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: a combined study using the section-Golgi method and calbindin D28k immunocytochemistry
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The striopallidal neuron: a main locus for adenosine-dopamine interactions in the brain
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Adenosine and glutamate extracellular concentrations and mitogen-activated protein kinases in the striatum of Huntington transgenic mice. Selective antagonism of adenosine A2A receptors reduces transmitter outflow
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Mechanisms of neurodegeneration in Huntington's disease.
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Relationship between motor and cognitive disorders in Huntington's disease
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The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease
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Reactive oxygen species and the central nervous system
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A primate model of Huntington's disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon
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Selective inhibition of the tricarboxylic acid cycle of GABAergic neurons with 3-nitropropionic acid in vivo
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CNS at the cellular level: identity of transmitter agents
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Ultrastructural localization of adenosine A2A receptors suggests multiple cellular sites for modulation of GABAergic neurons in rat striatum
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Apoptosis in Huntington's disease.
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A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.
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Adenosine receptors as therapeutic targets
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Regulation of proteins affecting NMDA receptor-induced excitotoxicity in a Huntington's mouse model
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Patterns of intellectual deficit in Huntington's disease
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Huntington's disease.
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7 January 2021
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Progression of symptoms in the early and middle stages of Huntington disease
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GABA signalling: therapeutic targets for epilepsy, Parkinson's disease and Huntington's disease
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A worldwide study of the Huntington's disease mutation. The sensitivity and specificity of measuring CAG repeats
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7 January 2021
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GABA(B) receptors at glutamatergic synapses in the rat striatum
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7 January 2021
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Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's disease
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7 January 2021
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Abnormal ocular motor control in Huntington's disease
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7 January 2021
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Genetic mouse models of Huntington's and Parkinson's diseases: illuminating but imperfect
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7 January 2021
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Huntington's disease: a synaptopathy?
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7 January 2021
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Calcium homeostasis and mitochondrial dysfunction in striatal neurons of Huntington disease
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7 January 2021
based on heuristic
inferred from DOI database lookup
Characteristic patterns of verbal memory function in patients with Huntington's disease
1 reference
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7 January 2021
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inferred from DOI database lookup
Huntingtin fragmentation and increased caspase 3, 8 and 9 activities in lymphoblasts with heterozygous and homozygous Huntington's disease mutation
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial DNA haplogroups do not influence the Huntington's disease phenotype
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
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7 January 2021
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Cerebrospinal fluid acetylcholinesterase and choline measurements in Huntington's disease
1 reference
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https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
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7 January 2021
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Mouse models of Huntington's disease
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https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
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7 January 2021
based on heuristic
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The selective vulnerability of striatopallidal neurons
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https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
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Role of adenosine A2A receptors in parkinsonian motor impairment and l-DOPA-induced motor complications
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Neuropsychological deficits in early, middle, and late stage Huntington's disease as measured by the Luria-Nebraska Neuropsychological Battery
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Huntington's disease: a review of the literature on prevalence and treatment of neuropsychiatric phenomena
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7 January 2021
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inferred from DOI database lookup
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes
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7 January 2021
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inferred from DOI database lookup
Presynaptic modulation by GABAB receptors of glutamatergic excitation and GABAergic inhibition of neostriatal neurons
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study.
1 reference
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https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Huntington's chorea. Deficiency of gamma-aminobutyric acid in brain
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7 January 2021
based on heuristic
inferred from DOI database lookup
Huntington's disease as a model for mood disorders. Clues from neuropathology and neurochemistry
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7 January 2021
based on heuristic
inferred from DOI database lookup
Plastic and behavioral abnormalities in experimental Huntington's disease: a crucial role for cholinergic interneurons
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7 January 2021
based on heuristic
inferred from DOI database lookup
Language functions in Huntington's disease
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reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Animal models of Huntington's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recent advances in understanding the pathogenesis of Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased glutamic acid and increased 5-hydroxytryptamine in Huntington's disease brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type huntingtin protects from apoptosis upstream of caspase-3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pathophysiology of Huntington's disease: an update
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The quinolinic acid model of Huntington's disease: locomotor abnormalities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distribution of adenosine A2 receptor mRNA in the human brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased rate of suicide among patients with Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of GABA metabolism: Implications for Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
II. Excitotoxic models for neurodegenerative disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synaptic relationships between dopaminergic afferents and cortical or thalamic input in the sensorimotor territory of the striatum in monkey
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dopamine turnover and glutathione oxidation: implications for Parkinson disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Behavioural correlates of striatal glial fibrillary acidic protein in the 3-nitropropionic acid rat model: disturbed walking pattern and spatial orientation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of overexpression of huntingtin proteins on mitochondrial integrity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntington's disease: correlations of mental status with chorea
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ornithine aminotransferase in Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of the basal ganglia in habit formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NMDA receptor losses in putamen from patients with Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970238-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1734-1140(10)70238-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20360611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PubMed publication ID
20360611
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20360611
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360611%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
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