(Q37733990)

English

Gene expression profiling of patient-derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts

scientific article published on 08 March 2017

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scholarly article

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Europe PubMed Central

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22 August 2017

Gene expression profiling of patient-derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts (English)

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Europe PubMed Central

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22 August 2017

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ChEBI release 2020-05-28

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based on heuristic

inferred from title

pancreatic cancer

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based on heuristic

inferred from title

1

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31 May 2020

Jean Robert Delpero

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31 May 2020

16

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31 May 2020

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31 May 2020

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31 May 2020

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31 May 2020

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31 May 2020

24

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Gwen Lomberk

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31 May 2020

author name string

Martin Bigonnet

2

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31 May 2020

Odile Gayet

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31 May 2020

Celine Loncle

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31 May 2020

Aurélie Maignan

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31 May 2020

Marine Gilabert

6

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31 May 2020

Vincent Moutardier

7

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31 May 2020

Stephane Garcia

8

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31 May 2020

Olivier Turrini

9

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31 May 2020

Marc Giovannini

11

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31 May 2020

Philippe Grandval

12

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31 May 2020

Mohamed Gasmi

13

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31 May 2020

Mehdi Ouaissi

14

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31 May 2020

Veronique Secq

15

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31 May 2020

Laetitia Marisa

19

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31 May 2020

Marion Rubis

20

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31 May 2020

Jean-Luc Raoul

21

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31 May 2020

James E Bradner

22

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31 May 2020

Jun Qi

23

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31 May 2020

Raul Urrutia

25

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31 May 2020

Andres Saul

26

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Europe PubMed Central

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31 May 2020

language of work or name

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publication date

8 March 2017

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22 August 2017

EMBO Molecular Medicine

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28275007%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

9

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28275007%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

4

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28275007%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

482-497

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28275007%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Clinical Response of Carcinomas Harboring the BRD4-NUT Oncoprotein to the Targeted Bromodomain Inhibitor OTX015/MK-8628

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5376755

23 August 2017

CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5376755

23 August 2017

Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5376755

23 August 2017

MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5376755

23 August 2017

BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5376755

23 August 2017

Registered report: BET bromodomain inhibition as a therapeutic strategy to target c-Myc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5376755

23 August 2017

Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets

1 reference

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23 August 2017

Whole genomes redefine the mutational landscape of pancreatic cancer

1 reference

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23 August 2017

Therapeutic strategies to inhibit MYC

1 reference

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23 August 2017

Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis.

1 reference

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23 August 2017

CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma

1 reference

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23 August 2017

Inhibition of bromodomain proteins for the treatment of human diffuse large B-cell lymphoma.

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23 August 2017

Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer

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23 August 2017

Small-molecule inhibitors of the Myc oncoprotein

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23 August 2017

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia

1 reference

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23 August 2017

Affinity map of bromodomain protein 4 (BRD4) interactions with the histone H4 tail and the small molecule inhibitor JQ1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5376755

23 August 2017

A modular and flexible ESC-based mouse model of pancreatic cancer.

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23 August 2017

c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells

1 reference

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23 August 2017

Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer.

1 reference

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23 August 2017

Targeting MYCN in neuroblastoma by BET bromodomain inhibition

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23 August 2017

Evolution and dynamics of pancreatic cancer progression

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23 August 2017

MYC on the path to cancer

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23 August 2017

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23 August 2017

Targeting MYC dependence in cancer by inhibiting BET bromodomains

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23 August 2017

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5376755

23 August 2017

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer

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23 August 2017

Selective inhibition of BET bromodomains

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23 August 2017

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23 August 2017

Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios

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23 August 2017

Modelling Myc inhibition as a cancer therapy

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23 August 2017

Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1.

1 reference

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23 August 2017

A faster circular binary segmentation algorithm for the analysis of array CGH data

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23 August 2017

Balance of Yin and Yang: ubiquitylation-mediated regulation of p53 and c-Myc

1 reference

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23 August 2017

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

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23 August 2017

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23 August 2017

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23 August 2017

Controlling the false discovery rate in behavior genetics research

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23 August 2017

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

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23 August 2017

MYC oncogenes and human neoplastic disease

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23 August 2017

The role of c-myc in cellular growth control

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23 August 2017

Mechanisms of apoptosis by c-Myc

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23 August 2017

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23 August 2017

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial

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23 August 2017

Toward stratification of patients with pancreatic cancer: Past lessons from traditional approaches and future applications with physical biomarkers

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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28 September 2017

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28 September 2017

The BET bromodomain inhibitor JQ1 suppresses growth of pancreatic ductal adenocarcinoma in patient-derived xenograft models.

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23 June 2018

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1 September 2018

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1 September 2018

c-MYC activation in primary and metastatic ductal adenocarcinoma of the pancreas: incidence, mechanisms, and clinical significance

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Bromodomain: A New Target in Emerging Epigenetic Medicine

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12 December 2020

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MYC: A Stratification Marker for Pancreatic Cancer Therapy

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.15252/EMMM.201606975

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28275007%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28275007%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28275007%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

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