(Q37737237)

22 August 2017

FOXO1 couples metabolic activity and growth state in the vascular endothelium (English)

1 reference

22 August 2017

0 references

13

1 reference

22 August 2017

Claudio A Franco

9

0 references

Michael Potente

Michael Potente

18

0 references

Marcus Fruttiger

Marcus Fruttiger

12

0 references

Holger Gerhardt

Holger Gerhardt

16

0 references

Thomas Braun

Thomas Braun

11

0 references

Jens C Brüning

15

Jens C Brüning

1 reference

22 August 2017

17

Peter Carmeliet

1 reference

22 August 2017

7

Barbara Zimmermann

1 reference

22 August 2017

Radiance Lim

6

0 references

Charles Keller

Charles Keller

14

0 references

author name string

Kerstin Wilhelm

1

1 reference

22 August 2017

Katharina Happel

2

1 reference

22 August 2017

Guy Eelen

3

1 reference

22 August 2017

Sandra Schoors

4

1 reference

22 August 2017

Mark F Oellerich

5

1 reference

22 August 2017

Irene M Aspalter

8

1 reference

22 August 2017

Thomas Boettger

10

1 reference

22 August 2017

language of work or name

English

0 references

publication date

6 January 2016

1 reference

22 August 2017

5

1 reference

based on heuristic

inferred from page(s)

published in

Nature

1 reference

22 August 2017

529

1 reference

22 August 2017

7585

1 reference

22 August 2017

216-220

1 reference

describes a project that uses

22 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5380221/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nature16498

0 references

cites work

FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

MYC, metabolism, cell growth, and tumorigenesis.

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

The embryonic mouse hindbrain as a qualitative and quantitative model for studying the molecular and cellular mechanisms of angiogenesis

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Metabolic reprogramming: a cancer hallmark even warburg did not anticipate

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Basic and therapeutic aspects of angiogenesis

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Understanding the Warburg effect: the metabolic requirements of cell proliferation

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

FoxO transcription factors in the maintenance of cellular homeostasis during aging

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

A global double-fluorescent Cre reporter mouse

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Molecular regulation of angiogenesis and lymphangiogenesis

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Transcriptional regulation and transformation by Myc proteins

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrow

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Analysis of C-MYC function in normal cells via conditional gene-targeted mutation

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Identification of CDK4 as a target of c-MYC.

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Metabolism of stromal and immune cells in health and disease

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Role of endothelial cell metabolism in vessel sprouting.

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

FOXOs: signalling integrators for homeostasis maintenance

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Angiopoietin-1 modulates endothelial cell function and gene expression via the transcription factor FKHR (FOXO1).

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

FoxO3A promotes metabolic adaptation to hypoxia by antagonizing Myc function

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Involvement of Foxo transcription factors in angiogenesis and postnatal neovascularization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

FoxO1 is required in endothelial but not myocardial cell lineages during cardiovascular development.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Efficient, inducible Cre-recombinase activation in vascular endothelium.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380221

1 September 2018

Identifiers

DOI

10.1038/NATURE16498

1 reference

Dimensions Publication ID

22 August 2017

0 references

1 reference

22 August 2017

1 reference