(Q37739321)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20429043%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

review article

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title

Lipids, mitochondria and cell death: implications in neuro-oncology (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20429043%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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0 references

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20429043%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Alison Colquhoun

series ordinal

1

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22 August 2017

publication date

29 April 2010

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20429043%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

published in

Molecular Neurobiology

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20429043%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

42

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20429043%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

issue

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20429043%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

page(s)

76-88

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20429043%20AND%20SRC:MED&resulttype=core&format=json

Gamma-linolenic acid (GLA) is cytotoxic to 36B10 malignant rat astrocytoma cells but not to 'normal' rat astrocytes

1 February 2020

cites work

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https://api.crossref.org/works/10.1007%2FS12035-010-8134-4

Gamma-linolenic acid alters the composition of mitochondrial membrane subfractions, decreases outer mitochondrial membrane binding of hexokinase and alters carnitine palmitoyltransferase I properties in the Walker 256 rat tumour.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8134-4

Selected eicosanoids increase the proliferation rate of human colon carcinoma cell lines and mouse colonocytes in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8134-4

gamma-Linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8134-4

Contact sites between mitochondrial envelope membranes. Structure and function in energy- and protein-transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8134-4

Enrichment of carnitine palmitoyltransferases I and II in the contact sites of rat liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8134-4

Cholate extracts of mitochondrial outer membranes increase inhibition by malonyl-CoA of carnitine palmitoyltransferase-I by a mechanism involving phospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8134-4

Comparative anti-mitotic effects of lithium gamma-linolenate, gamma-linolenic acid and arachidonic acid, on transformed and embryonic cells

21 January 2018

1 reference

12 December 2020

Regulation of tumour cell fatty acid oxidation by n-6 polyunsaturated fatty acids.

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12 December 2020

Protective role of glucose-6-phosphate dehydrogenase activity in the metabolic response of C6 rat glioma cells to polyunsaturated fatty acid exposure.

1 reference

12 December 2020

A metabolic role for mitochondria in palmitate-induced cardiac myocyte apoptosis

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12 December 2020

Distinct kinetics of carnitine palmitoyltransferase i in contact sites and outer membranes of rat liver mitochondria

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12 December 2020

Oxidative stress and adenine nucleotide control of mitochondrial permeability transition.

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12 December 2020

Effect of dietary 18-carbon fatty acids on growth of transplantable mammary adenocarcinomas in mice

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12 December 2020

Mechanisms of omega-3 fatty acid-induced growth inhibition in MDA-MB-231 human breast cancer cells

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12 December 2020

Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma

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12 December 2020

Polyunsaturated fatty acids augment free radical generation in tumor cells in vitro

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12 December 2020

A pivotal role for p53: balancing aerobic respiration and glycolysis

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12 December 2020

Gamma-linolenic acid therapy of human gliomas

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12 December 2020

Intratumoral gamma-linoleic acid therapy of human gliomas

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12 December 2020

Profiles of the fatty acids in the plasma membrane of human brain tumors

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12 December 2020

A Positive Role for the Ku Complex in DNA Replication Following Strand Break Damage in Mammals

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12 December 2020

The stimulation of ketogenesis by cannabinoids in cultured astrocytes defines carnitine palmitoyltransferase I as a new ceramide-activated enzyme

1 reference

12 December 2020

Mitochondria as the central control point of apoptosis

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12 December 2020

Morphologic effects of sulfur-substituted fatty acids on rat hepatocytes with special reference to proliferation of peroxisomes and mitochondria

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12 December 2020

Inhibition of the Expression of VE-Cadherin/Catenin Complex by Gamma Linolenic Acid in Human Vascular Endothelial Cells, and Its Impact on Angiogenesis

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12 December 2020

Tumor suppressors and cell metabolism: a recipe for cancer growth

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12 December 2020

Relative biological effectiveness of high-energy iron ions for micronucleus formation at low doses.

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12 December 2020

Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis

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12 December 2020

Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers' most common phenotypes, the "Warburg Effect", i.e., elevated glycolysis in the presence of oxygen

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12 December 2020

The induction of apoptosis in human cervical carcinoma (HeLa) cells by gamma-linolenic acid

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12 December 2020

The eicosanoid cascade: possible role in gliomas and meningiomas

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12 December 2020

The fatty acid composition of human gliomas differs from that found in nonmalignant brain tissue

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12 December 2020

Effect of n-6 and n-3 fatty acids on the survival of vincristine sensitive and resistant human cervical carcinoma cells in vitro.

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12 December 2020

Docosahexaenoic acid accumulates in cardiolipin and enhances HT-29 cell oxidant production.

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12 December 2020

Inhibition of Ku autoantigen binding activity to the E2F motif after ultraviolet B irradiation of melanocytic cells.

1 reference

12 December 2020

High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase

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12 December 2020

Highly unsaturated fatty acid induced tumour regression in glioma pharmacodynamics and bioavailability of gamma linolenic acid in an implantation glioma model: effects on tumour biomass, apoptosis and neuronal tissue histology

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12 December 2020

Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis

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12 December 2020

Gamma linolenic acid with tamoxifen as primary therapy in breast cancer

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12 December 2020

ShRNA-mediated Ku80 gene silencing inhibits cell proliferation and sensitizes to gamma-radiation and mitomycin C-induced apoptosis in esophageal squamous cell carcinoma lines

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12 December 2020

Some effects of the essential fatty acids linoleic acid and alpha-linolenic acid and of their metabolites gamma-linolenic acid, arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid, and of prostaglandins A1 and E1 on the proliferation of hu

1 reference

12 December 2020

Actuality of Warburg's views in our understanding of renal cancer metabolism.

1 reference

12 December 2020

Mitochondria as targets for cancer chemotherapy

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12 December 2020

Tumoricidal action of cis-unsaturated fatty acids and their relationship to free radicals and lipid peroxidation

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12 December 2020

Adaptive landscapes and emergent phenotypes: why do cancers have high glycolysis?

1 reference

12 December 2020

Effects of gamma-linolenic acid and arachidonic acid on cell cycle progression and apoptosis induction in normal and transformed cells

1 reference

12 December 2020

Effects of polyunsaturated fatty acids on the efficacy of antineoplastic agents toward L5178Y lymphoma cells

1 reference

12 December 2020

Enhancement of radiosensitivity by roscovitine pretreatment in human non-small cell lung cancer A549 cells

1 reference

12 December 2020

Specific fatty acids and human colorectal cancer: an overview

1 reference

12 December 2020

Eicosapentaenoic acid and docosahexaenoic acid effects on tumour mitochondrial metabolism, acyl CoA metabolism and cell proliferation.

1 reference

12 December 2020

Docosahexaenoic acid induces apoptosis in Jurkat cells by a protein phosphatase-mediated process

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12 December 2020

Mitochondria in cancer: not just innocent bystanders

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12 December 2020

Migration patterns and breast cancer risk in Asian-American women

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12 December 2020

Induction of apoptosis by polyunsaturated fatty acids and its relationship to fatty acid inhibition of carnitine palmitoyltransferase I activity in Hep2 cells

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12 December 2020

Differential killing of human carcinoma cells supplemented with n-3 and n-6 polyunsaturated fatty acids

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12 December 2020

Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells

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12 December 2020

Evidence for an impaired long-chain fatty acid oxidation and ketogenesis in Fao hepatoma cells

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12 December 2020

The AMP-activated protein kinase is involved in the regulation of ketone body production by astrocytes

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12 December 2020

Relationship between dietary fat and experimental mammary tumorigenesis: a review and critique

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12 December 2020

Role of mitochondria as the gardens of cell death

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12 December 2020

Approaches to mitochondrially mediated cancer therapy

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12 December 2020

Mechanisms of action of eicosapentaenoic acid in bladder cancer cells in vitro: alterations in mitochondrial metabolism, reactive oxygen species generation and apoptosis induction

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12 December 2020

Modifications in mitochondrial metabolism and ultrastructure and their relationship to tumour growth inhibition by gamma-linolenic acid

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12 December 2020

Direct interaction of the mitochondrial membrane protein carnitine palmitoyltransferase I with Bcl-2

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12 December 2020

Fatty acid regulation of breast cancer cell growth and invasion

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12 December 2020

Bcl-2 family proteins as regulators of oxidative stress

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12 December 2020

Cell-cycle arrest in Jurkat leukaemic cells: a possible role for docosahexaenoic acid

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12 December 2020

Homophilic anchorage of brain-hexokinase to mitochondria-porins revealed by specific-peptide antibody cross recognition

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12 December 2020

Mitochondria, oxidative stress and cell death

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12 December 2020

The 2007 WHO classification of tumours of the central nervous system

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12 December 2020

Oxidation of pyridine nucleotides during Fas- and ceramide-induced apoptosis in Jurkat cells: correlation with changes in mitochondria, glutathione depletion, intracellular acidification and caspase 3 activation

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12 December 2020

Polyunsaturated fatty acids induce tight junctions to form in brain capillary endothelial cells

1 reference

12 December 2020

Gamma-linolenic acid alters Ku80, E2F1, and bax expression and induces micronucleus formation in C6 glioma cells in vitro

1 reference

12 December 2020

Metabolism of n -9, n -6 and n -3 fatty acids in hepatoma Morris 7777 cells. Preferential accumulation of linoleic acid in cardiolipin

1 reference

12 December 2020

Effect of altering dietary omega-6/omega-3 fatty acid ratios on prostate cancer membrane composition, cyclooxygenase-2, and prostaglandin E2

1 reference

12 December 2020

Immunodetection of rat Walker 256 tumour mitochondrial carnitine palmitoyltransferase I and II: evidence for the control of CPT II expression by insulin

1 reference

12 December 2020

Rat liver mitochondrial contact sites and carnitine palmitoyltransferase-I.

1 reference

12 December 2020

Intracellular unesterified arachidonic acid signals apoptosis

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12 December 2020

Regulation of cell division in a human glioma cell clone by arachidonic acid and alpha-tocopherolquinone.

1 reference

12 December 2020

Uptake and distribution of cis-unsaturated fatty acids and their effect on free radical generation in normal and tumor cells in vitro

1 reference

12 December 2020

Polyunsaturated fatty acid-induced cytotoxicity against tumor cells and its relationship to lipid peroxidation

1 reference

12 December 2020

Intracellular oxidation by human glioma cell populations: effect of arachidonic acid

1 reference

12 December 2020

Role of NF-kappaB and DNA repair protein Ku on apoptosis in pancreatic acinar cells

1 reference

12 December 2020

Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy

1 reference

12 December 2020

Identification of new tyrosine phosphorylated proteins in rat brain mitochondria

1 reference

12 December 2020

Arachidonic acid interaction with the mitochondrial electron transport chain promotes reactive oxygen species generation

1 reference

12 December 2020

Role of carnitine palmitoyltransferase I in the control of ketogenesis in primary cultures of rat astrocytes

1 reference

12 December 2020

Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis

1 reference

12 December 2020

Gamma-linolenic acid therapy of human glioma-a review of in vitro, in vivo, and clinical studies.

1 reference

12 December 2020

Voltage-dependent anion channel 1-based peptides interact with hexokinase to prevent its anti-apoptotic activity

1 reference

12 December 2020

Essential fatty acids: molecular and cellular basis of their anti-cancer action and clinical implications.

1 reference

12 December 2020

Dietary polyunsaturated fatty acids as inducers of apoptosis: implications for cancer.

1 reference

12 December 2020

Apoptotic death of pancreatic cancer cells induced by polyunsaturated fatty acids varies with double bond number and involves an oxidative mechanism

1 reference

12 December 2020

Docosahexaenoic acid, a major constituent of fish oil diets, prevents activation of cyclin-dependent kinases and S-phase entry by serum stimulation in HT-29 cells

1 reference

12 December 2020

Hypoxia, glucose metabolism and the Warburg's effect.

1 reference

12 December 2020

Effect of dietary polyunsaturated fatty acids on growth of mammary adenocarcinomas in mice and rats

1 reference

12 December 2020

Pathophysiological and pharmacological implications of mitochondria-targeted reactive oxygen species generation in astrocytes

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12 December 2020

Cellular energetic metabolism of cerebral tissue: metabolic characteristics of glial tumours

1 reference

12 December 2020

Antitumor effect of gamma-linolenic acid on cultured human neuroblastoma cells

1 reference

12 December 2020

Putative partners in Bax mediated cytochrome-c release: ANT, CypD, VDAC or none of them?

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12 December 2020

A radical approach to cancer.

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12 December 2020

Can tumour cell drug resistance be reversed by essential fatty acids and their metabolites?

1 reference

12 December 2020

Hexokinase-I protection against apoptotic cell death is mediated via interaction with the voltage-dependent anion channel-1: mapping the site of binding.

1 reference

12 December 2020

Dynamics of reactive oxygen intermediate production in human glioma: n-6 essential fatty acid effects.

1 reference

12 December 2020

Homeostatic functions of the p53 tumor suppressor: regulation of energy metabolism and antioxidant defense

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12 December 2020

Dietary fish oil inhibits human breast carcinoma growth: a function of increased lipid peroxidation

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12 December 2020

Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis

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12 December 2020

From bench to the clinic: gamma-linolenic acid therapy of human gliomas

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12 December 2020

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

1 reference

12 December 2020

Polyunsaturated fatty acids increase the sensitivity of 36B10 rat astrocytoma cells to radiation-induced cell kill

1 reference

12 December 2020

Regulation of mitochondrial hexokinase in cultured HT 29 human cancer cells. An ultrastructural and biochemical study

1 reference

12 December 2020

Effects of N-6 essential fatty acids on glioma invasion and growth: experimental studies with glioma spheroids in collagen gels.

1 reference

12 December 2020

Cardiolipin: setting the beat of apoptosis

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12 December 2020

Colon cancer, fatty acids and anti-inflammatory compounds

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12 December 2020

Docosahexaenoic acid inhibits cancer cell growth via p27Kip1, CDK2, ERK1/ERK2, and retinoblastoma phosphorylation.

1 reference

12 December 2020

Energy metabolism in astrocytes: high rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis

1 reference

12 December 2020

Oxygen metabolism and a potential role for cytochrome c oxidase in the Warburg effect

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12 December 2020

Fatty acid oxidation and ketogenesis by astrocytes in primary culture

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12 December 2020

The mitochondrial permeability transition pore and its role in cell death

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12 December 2020

Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II.

1 reference

12 December 2020

Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors

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12 December 2020

Apoptosis in human primary brain tumours: actions of arachidonic acid

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12 December 2020

Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression

1 reference

12 December 2020

Transplanted glioma cells migrate and proliferate on host brain vasculature: a dynamic analysis

1 reference

12 December 2020

Enhancement of doxorubicin cytotoxicity by polyunsaturated fatty acids in the human breast tumor cell line MDA-MB-231: relationship to lipid peroxidation.

1 reference

12 December 2020

Mitochondria as targets for chemotherapy

1 reference

12 December 2020

The Mediterranean diets: What is so special about the diet of Greece? The scientific evidence.

1 reference

12 December 2020

Local application of γ-linolenic acid in the treatment of human gliomas

1 reference

12 December 2020

Effect of varying proportions of dietary menhaden and corn oil on experimental rat mammary tumor promotion.

1 reference

12 December 2020

Dietary supplementation with eicosapentaenoic and docosahexaenoic acid inhibits growth of Morris hepatocarcinoma 3924A in rats: effects on proliferation and apoptosis

1 reference

12 December 2020

The biology of Ku and its potential oncogenic role in cancer.

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12 December 2020

The selective cytotoxicity of gamma-linolenic acid (GLA) is associated with increased oxidative stress.

1 reference

12 December 2020

Effects of dietary omega-3 fatty acids on human breast cancer growth and metastases in nude mice

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12 December 2020

Human and rat tumour cells possess mitochondrial carnitine palmitoyltransferase I and II: effects of insulin

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12 December 2020

Dietary factors and growth and metabolism in experimental tumors

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12 December 2020

Effects of saturated and polyunsaturated fatty acids on human tumor-cell proliferation

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12 December 2020

Long chain fatty acids inhibit and medium chain fatty acids activate mammalian cardiac hexokinase

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12 December 2020

Mitochondrial matrix granules: their behavior during changing metabolic situations and their relationship to contact sites between inner and outer mitochondrial membranes

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12 December 2020

Omega-3 fatty acids as cancer chemopreventive agents

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12 December 2020

Metabolic fate and effects of saturated and unsaturated fatty acids in Hep2 human larynx tumor cells

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12 December 2020

Mitochondrial medicine and mitochondrion-based therapeutics☆

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12 December 2020

Docosahexaenoic acid is a potent inducer of apoptosis in HT-29 colon cancer cells

1 reference

12 December 2020

Ku is involved in cell growth, DNA replication and G1-S transition.

1 reference

12 December 2020

10.1007/S12035-010-8134-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20429043%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference