(Q37739432)

22 August 2017

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title

Pharmacogenomics of pediatric acute lymphoblastic leukemia (English)

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22 August 2017

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Nathan D Meeker

1

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22 August 2017

Jun J Yang

series ordinal

2

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22 August 2017

Joshua D Schiffman

series ordinal

3

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22 August 2017

language of work or name

English

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publication date

1 July 2010

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Expert Opinion on Pharmacotherapy

22 August 2017

published in

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22 August 2017

volume

11

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22 August 2017

issue

10

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22 August 2017

page(s)

1621-1632

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Cancer survivorship: a pediatric perspective

22 August 2017

cites work

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Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

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Prognostic importance of TLX1 (HOX11) oncogene expression in adults with T-cell acute lymphoblastic leukaemia.

21 January 2018

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Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

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New genetic abnormalities and treatment response in acute lymphoblastic leukemia

21 January 2018

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A set of genes that regulate cell proliferation predicts treatment outcome in childhood acute lymphoblastic leukemia

21 January 2018

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Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment

21 January 2018

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Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia

21 January 2018

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Quantitative analysis of minimal residual disease predicts relapse in children with B-lineage acute lymphoblastic leukemia in DFCI ALL Consortium Protocol 95-01.

21 January 2018

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Pharmacogenetics of minimal residual disease response in children with B-precursor acute lymphoblastic leukemia: a report from the Children's Oncology Group

21 January 2018

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Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase

21 January 2018

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Polymorphisms of xenobiotic metabolizing enzymes and DNA repair genes and outcome in childhood acute lymphoblastic leukemia.

21 January 2018

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Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia

21 January 2018

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CYP3A genotypes and treatment response in paediatric acute lymphoblastic leukaemia

21 January 2018

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Pharmacogenetics of outcome in children with acute lymphoblastic leukemia

21 January 2018

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Effects of prednisone and genetic polymorphisms on etoposide disposition in children with acute lymphoblastic leukemia

21 January 2018

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Glutathione S-transferase genotypes, genetic susceptibility, and outcome of therapy in childhood acute lymphoblastic leukemia

21 January 2018

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Polymorphisms within glutathione S-transferase genes and initial response to glucocorticoids in childhood acute lymphoblastic leukaemia.

21 January 2018

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GSTP1 and MDR1 genotypes and central nervous system relapse in childhood acute lymphoblastic leukemia

21 January 2018

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Ancestry and pharmacogenetics of antileukemic drug toxicity

21 January 2018

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Functional C3435T polymorphism of MDR1 gene: an impact on genetic susceptibility and clinical outcome of childhood acute lymphoblastic leukemia.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Polymorphisms in multidrug resistance-associated protein gene 4 is associated with outcome in childhood acute lymphoblastic leukemia

21 January 2018

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Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia

21 January 2018

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DNA variants in the dihydrofolate reductase gene and outcome in childhood ALL.

21 January 2018

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Methylenetetrahydrofolate reductase polymorphisms and therapy response in pediatric acute lymphoblastic leukemia

21 January 2018

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Role of polymorphisms in MTHFR and MTHFD1 genes in the outcome of childhood acute lymphoblastic leukemia

21 January 2018

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Additional genetic risk factor for death in children with acute lymphoblastic leukemia: a common polymorphism of the MTHFR gene

21 January 2018

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MTHFR polymorphisms' influence on outcome and toxicity in acute lymphoblastic leukemia patients.

21 January 2018

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Pharmacogenetics of cancer therapy: getting personal

21 January 2018

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https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Pharmacogenomics--drug disposition, drug targets, and side effects

21 January 2018

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https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism

21 January 2018

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Severe 6-thioguanine-induced marrow aplasia in a child with acute lymphoblastic leukemia and inherited thiopurine methyltransferase deficiency

21 January 2018

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Human kidney thiopurine methyltransferase. Purification and biochemical properties.

21 January 2018

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Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia

21 January 2018

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Thiopurine methyltransferase activity is related to the risk of relapse of childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study

21 January 2018

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Drug methylation in cancer therapy: lessons from the TPMT polymorphism

21 January 2018

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Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance

21 January 2018

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Human thiopurine S-methyltransferase pharmacogenetics: variant allozyme misfolding and aggresome formation

21 January 2018

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Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia

21 January 2018

1 reference

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Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine

21 January 2018

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Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study

21 January 2018

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High incidence of secondary brain tumours after radiotherapy and antimetabolites.

21 January 2018

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Possible carcinogenic effect of 6-mercaptopurine on bone marrow stem cells: relation to thiopurine metabolism

21 January 2018

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Treating childhood acute lymphoblastic leukemia without cranial irradiation

21 January 2018

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Thiopurine methyltransferase in acute lymphoblastic leukemia

21 January 2018

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Richard Weinshilboum: Pharmacogenetics: The future is here!

21 January 2018

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TPMT, UGT1A1 and DPYD: genotyping to ensure safer cancer therapy?

21 January 2018

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https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Genetic polymorphism of inosine-triphosphate-pyrophosphatase influences mercaptopurine metabolism and toxicity during treatment of acute lymphoblastic leukemia individualized for thiopurine-S-methyl-transferase status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Predictors of oral mucositis in patients receiving hematopoietic cell transplants for chronic myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Pharmacogenetics of methotrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Pharmacogenetic risk factors for osteonecrosis of the hip among children with leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Methotrexate pharmacokinetics in transgenic mice with liver-specific expression of human organic anion-transporting polypeptide 1B1 (SLCO1B1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Does pharmacokinetic variability influence the efficacy of high-dose methotrexate for the treatment of children with acute lymphoblastic leukemia: what can we learn from small studies?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

The role of glutathione-S-transferase in anti-cancer drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

The GSTT1 deletion polymorphism is associated with initial response to glucocorticoids in childhood acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Glucocorticoid-induced apoptosis and glucocorticoid resistance: molecular mechanisms and clinical relevance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Genetic predictors of glucocorticoid-induced hypertension in children with acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Response to glucocorticoids and toxicity in childhood acute lymphoblastic leukemia: role of polymorphisms of genes involved in glucocorticoid response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Osteonecrosis as a complication of treating acute lymphoblastic leukemia in children: a report from the Children's Cancer Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Magnetic resonance imaging detection of avascular necrosis of the bone in children receiving intensive prednisone therapy for acute lymphoblastic leukemia or non-Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

A PAI-1 (SERPINE1) polymorphism predicts osteonecrosis in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Vincristine pharmacokinetics after repetitive dosing in children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Decrease in motor performance in children with cancer is independent of the cumulative dose of vincristine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Vincristine-induced neuropathy as the initial presentation of charcot-marie-tooth disease in acute lymphoblastic leukemia: a Pediatric Oncology Group study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Selective metabolism of vincristine in vitro by CYP3A5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Influence of functional polymorphisms of the MDR1 gene on vincristine pharmacokinetics in childhood acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Expression of SMARCB1 modulates steroid sensitivity in human lymphoblastoid cells: identification of a promoter SNP that alters PARP1 binding and SMARCB1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Pharmacogenetics in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

The SWI/SNF chromatin-remodeling complex and glucocorticoid resistance in acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Immunophenotyping as a guide for targeted therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Prognostic significance of high-level FLT3 expression in MLL-rearranged infant acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Biologic pathways associated with relapse in childhood acute lymphoblastic leukemia: a Children's Oncology Group study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2010.484019

10.1517/14656566.2010.484019

21 January 2018

Identifiers

DOI

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22 August 2017

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