(Q37818144)

English

The evolution of population pharmacokinetic models to describe the enterohepatic recycling of mycophenolic acid in solid organ transplantation and autoimmune disease

scientific article published on January 2011

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scholarly article

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Europe PubMed Central

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17 January 2020

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Europe PubMed Central

The evolution of population pharmacokinetic models to describe the enterohepatic recycling of mycophenolic acid in solid organ transplantation and autoimmune disease (English)

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17 January 2020

organ transplantation

1 reference

based on heuristic

inferred from title

autoimmune disease

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

Catherine M Sherwin

1

1 reference

Europe PubMed Central

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17 January 2020

Alexander Vinks

5

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17 January 2020

author name string

Tsuyoshi Fukuda

2

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17 January 2020

Hermine I Brunner

3

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17 January 2020

Jens Goebel

4

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17 January 2020

publication date

1 January 2011

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17 January 2020

Clinical Pharmacokinetics

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17 January 2020

50

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17 January 2020

1

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17 January 2020

1-24

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17 January 2020

Consensus report on therapeutic drug monitoring of mycophenolic acid in solid organ transplantation

1 reference

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Pharmacokinetic role of protein binding of mycophenolic acid and its glucuronide metabolite in renal transplant recipients

1 reference

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The role of organic anion-transporting polypeptides and their common genetic variants in mycophenolic acid pharmacokinetics.

1 reference

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Pharmacokinetic modelling and development of Bayesian estimators for therapeutic drug monitoring of mycophenolate mofetil in reduced-intensity haematopoietic stem cell transplantation

1 reference

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A framework for assessing inter-individual variability in pharmacokinetics using virtual human populations and integrating general knowledge of physical chemistry, biology, anatomy, physiology and genetics: A tale of 'bottom-up' vs 'top-down' recogn

1 reference

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UGT genotype may contribute to adverse events following medication with mycophenolate mofetil in pediatric kidney transplant recipients

1 reference

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1 reference

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Population pharmacokinetics of mycophenolic acid : a comparison between enteric-coated mycophenolate sodium and mycophenolate mofetil in renal transplant recipients

1 reference

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Pharmacokinetics of mycophenolate mofetil and sirolimus in children.

1 reference

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23 June 2018

Population pharmacokinetic modelling for enterohepatic circulation of mycophenolic acid in healthy Chinese and the influence of polymorphisms in UGT1A9.

1 reference

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IMPDH1 gene polymorphisms and association with acute rejection in renal transplant patients

1 reference

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23 June 2018

Therapeutic drug monitoring of mycophenolic acid: does it improve patient outcome?

1 reference

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23 June 2018

Mycophenolic acid trough level monitoring in solid organ transplant recipients treated with mycophenolate mofetil: association with clinical outcome

1 reference

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23 June 2018

Time-dependent clearance of mycophenolic acid in renal transplant recipients

1 reference

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23 June 2018

Clinical pharmacokinetics and pharmacodynamics of mycophenolate in solid organ transplant recipients

1 reference

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Induction of human UDP-glucuronosyltransferase 1A1 by cortisol-GR.

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23 June 2018

Influence of nonsynonymous polymorphisms of UGT1A8 and UGT2B7 metabolizing enzymes on the formation of phenolic and acyl glucuronides of mycophenolic acid

1 reference

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23 June 2018

Methods to evaluate biliary excretion of drugs in humans: an updated review

1 reference

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23 June 2018

Therapeutic drug monitoring of mycophenolate mofetil in transplantation

1 reference

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Integration of hepatic drug transporters and phase II metabolizing enzymes: mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites

1 reference

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23 June 2018

Characterizing the role of enterohepatic recycling in the interactions between mycophenolate mofetil and calcineurin inhibitors in renal transplant patients by pharmacokinetic modelling.

1 reference

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23 June 2018

Mechanisms of action of mycophenolate mofetil

1 reference

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Predicting drug disposition via application of BCS: transport/absorption/ elimination interplay and development of a biopharmaceutics drug disposition classification system

1 reference

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Immunosuppressive drug monitoring - what to use in clinical practice today to improve renal graft outcome

1 reference

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23 June 2018

Characterization of a phase 1 metabolite of mycophenolic acid produced by CYP3A4/5.

1 reference

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23 June 2018

Stimulation of transcriptional expression of human UDP-glucuronosyltransferase 1A1 by dexamethasone

1 reference

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Pharmacogenomics of the OATP and OAT families

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Factors affecting variability in distribution of tacrolimus in liver transplant recipients

1 reference

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Population pharmacokinetic modeling of oral cyclosporin using NONMEM: comparison of absorption pharmacokinetic models and design of a Bayesian estimator

1 reference

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23 June 2018

Population pharmacokinetic analysis of mycophenolic acid in renal transplant recipients following oral administration of mycophenolate mofetil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5565486

23 June 2018

Mycophenolic Acid Pharmacodynamics and Pharmacokinetics Provide a Basis for Rational Monitoring Strategies

1 reference

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23 June 2018

Pharmacokinetic strategies in deciphering atypical drug absorption profiles

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23 June 2018

Enterohepatic circulation: physiological, pharmacokinetic and clinical implications

1 reference

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23 June 2018

The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes

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Glucuronide and glucoside conjugation of mycophenolic acid by human liver, kidney and intestinal microsomes

1 reference

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Expression and regulation of hepatic drug and bile acid transporters

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Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine

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Pharmacokinetic and metabolic investigations of mycophenolic acid in pediatric patients after renal transplantation: implications for therapeutic drug monitoring. German Study Group on Mycophenolate Mofetil Therapy in Pediatric Renal Transplant Reci

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Identification of uridine diphosphate glucuronosyltransferases involved in the metabolism and clearance of mycophenolic acid

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Clinical pharmacokinetics of mycophenolate mofetil

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Effects of food and antacid on the pharmacokinetics of single doses of mycophenolate mofetil in rheumatoid arthritis patients

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Circadian variation in gastric emptying of meals in humans

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Limited sampling models and Bayesian estimation for mycophenolic acid area under the curve prediction in stable renal transplant patients co-medicated with ciclosporin or sirolimus

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The acyl glucuronide metabolite of mycophenolic acid induces tubulin polymerization in vitro

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Mechanism-based enterohepatic circulation model of mycophenolic acid and its glucuronide metabolite: assessment of impact of cyclosporine dose in Asian renal transplant patients.

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Limited sampling strategies for therapeutic drug monitoring of mycophenolate mofetil therapy in patients with autoimmune disease.

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Effect of mycophenolate acyl-glucuronide on human recombinant type 2 inosine monophosphate dehydrogenase

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Current target ranges of mycophenolic acid exposure and drug-related adverse events: a 5-year, open-label, prospective, clinical follow-up study in renal allograft recipients.

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C-440T/T-331C polymorphisms in the UGT1A9 gene affect the pharmacokinetics of mycophenolic acid in kidney transplantation

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Population pharmacokinetics of mycophenolic acid in renal transplant recipients.

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Impact of mycophenolate mofetil loading on drug exposure in the early posttransplant period

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1 September 2018

Population pharmacokinetics of mycophenolic acid in kidney transplant pediatric and adolescent patients

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1 September 2018

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1 September 2018

Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism.

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1 September 2018

Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver.

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1 September 2018

The main role of UGT1A9 in the hepatic metabolism of mycophenolic acid and the effects of naturally occurring variants

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1 September 2018

Human UDP-glucuronosyltransferases show atypical metabolism of mycophenolic acid and inhibition by curcumin

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Drug interactions between mycophenolate and cyclosporine

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1 September 2018

Population pharmacokinetics and Bayesian estimation of mycophenolic acid concentrations in stable renal transplant patients

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1 September 2018

Cyclosporin A, but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by multidrug resistance-associated protein 2 in rats

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1 September 2018

An assessment of udp-glucuronosyltransferase induction using primary human hepatocytes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5565486

1 September 2018

Mycophenolate mofetil dose reduction and the risk of acute rejection after renal transplantation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5565486

1 September 2018

The impact of mycophenolate mofetil dosing patterns on clinical outcome after renal transplantation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5565486

1 September 2018

Glucocorticoids interfere with mycophenolate mofetil bioavailability in kidney transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5565486

1 September 2018

Effect of cyclosporine on mycophenolic acid area under the concentration-time curve in pediatric kidney transplant recipients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5565486

1 September 2018

Mixed effect modeling of sumatriptan pharmacokinetics during drug development: II. From healthy subjects to phase 2 dose ranging in patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5565486

1 September 2018

A compartmental absorption and transit model for estimating oral drug absorption.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5565486

1 September 2018

Identification of glucoside and carboxyl-linked glucuronide conjugates of mycophenolic acid in plasma of transplant recipients treated with mycophenolate mofetil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5565486

1 September 2018

Opportunities for therapeutic monitoring of mycophenolate mofetil dose in renal transplantation suggested by the pharmacokinetic/pharmacodynamic relationship for mycophenolic acid and suppression of rejection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5565486

1 September 2018

Pharmacokinetics and bioavailability of mycophenolate mofetil in healthy subjects after single-dose oral and intravenous administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5565486

1 September 2018

Transit compartments versus gamma distribution function to model signal transduction processes in pharmacodynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UDP-glucuronosyltransferases in human intestinal mucosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A time-lag model for pharmacokinetics of drugs subject to enterohepatic circulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trends and results for organ donation and transplantation in the United States, 2004

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance protein 2 genetic polymorphisms influence mycophenolic acid exposure in renal allograft recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacokinetic-pharmacodynamic relationship for mycophenolate mofetil in renal transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of UGT1A8 and UGT2B7 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circadian pharmacokinetics of mycophenolic Acid and implication of genetic polymorphisms for early clinical events in renal transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane transport of mycophenolate mofetil and its active metabolite, mycophenolic acid in MDCK and MDR1-MDCK cell monolayers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enterohepatic circulation model for population pharmacokinetic analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioavailability improvement of mycophenolic acid through amino ester derivatization

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/11536640-000000000-00000

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142265%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142265%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142265%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

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Wikiversity(0 entries)

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