(Q37829691)

24 August 2017

1 reference

title

Gain and loss of T cell subsets in old age--age-related reshaping of the T cell repertoire (English)

1 reference

Beatrix Grubeck-Loebenstein

24 August 2017

author

5

object named as

Beatrix Grubeck-Loebenstein

1 reference

Dietmar Herndler-Brandstetter

24 August 2017

4

object named as

Dietmar Herndler-Brandstetter

1 reference

24 August 2017

Christoph R Arnold

1

1 reference

24 August 2017

Juliane Wolf

2

1 reference

24 August 2017

Stefan Brunner

3

1 reference

24 August 2017

publication date

18 January 2011

1 reference

Journal of Clinical Immunology

24 August 2017

published in

1 reference

24 August 2017

volume

31

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24 August 2017

issue

2

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24 August 2017

page(s)

137-146

1 reference

https://scigraph.springernature.com/pub.10.1007/s10875-010-9499-x

24 August 2017

exact match

0 references

cites work

Biology of immune responses to vaccines in elderly persons

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Immunosenescence: role and measurement in influenza vaccine response among the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Life and death of lymphocytes: a role in immunesenescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Life after the thymus: CD31+ and CD31- human naive CD4+ T-cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Aging of hematopoietic stem cells is regulated by the stem cell niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Thymic involution with ageing: obsolescence or good housekeeping?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Evidence of premature immune aging in patients thymectomized during early childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Homeostasis and the age-associated defect of CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

21 January 2018

CD8 T cells and aging

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Naive T Cells in the Elderly: Are They Still There?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Aging and T-cell diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

The influence of age on T cell generation and TCR diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

TNF-alpha-induced apoptosis in human naïve and memory CD8+ T cells in aged humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

CD95-mediated apoptosis in naïve, central and effector memory subsets of CD4+ and CD8+ T cells in aged humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Memories are made of this: synergy of T cell receptor and cytokine signals in CD4(+) central memory cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

IL-7 is critical for homeostatic proliferation and survival of naive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

DNA damage and mutation: contributors to the age-related alterations in T cell-mediated immune responses?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Homeostasis of the naive CD4+ T cell compartment during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Post-thymic in vivo proliferation of naive CD4+ T cells constrains the TCR repertoire in healthy human adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

IL-15 induces antigen-independent expansion and differentiation of human naive CD8+ T cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Can the immune system still be efficient in the elderly? An immunological and immunoendocrine therapeutic perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Is immunosenescence infectious?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Clonal expansions and loss of receptor diversity in the naive CD8 T cell repertoire of aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

The effect of age on the cognate function of CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Antigen-independent changes in naive CD4 T cells with aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Age-dependent defects in TCR-triggered cytoskeletal rearrangement in CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Early activation defects in T lymphocytes from aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Analysis of Raf-1 activation in response to TCR activation and costimulation in murine T-lymphocytes: effect of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Effects of aging on T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Importance of culturing primary lymphocytes at physiological oxygen levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Reduced oxygen tension results in reduced human T cell proliferation and increased intracellular oxidative damage and susceptibility to apoptosis upon activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Regulation of naïve and memory T-cell homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Naïve to memory T-cell differentiation during homeostasis-driven proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

The generation of protective memory-like CD8+ T cells during homeostatic proliferation requires CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Memory inflation: continuous accumulation of antiviral CD8+ T cells over time.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Memory inflation during chronic viral infection is maintained by continuous production of short-lived, functional T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

IL-4-producing CD8+ T cells with a CD62L++(bright) phenotype accumulate in a subgroup of older adults and are associated with the maintenance of intact humoral immunity in old age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Organization of immunological memory by bone marrow stroma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Evidence for rapid disappearance of initially expanded HIV-specific CD8+ T cell clones during primary HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Cytotoxic T lymphocyte responses to human immunodeficiency virus: control and escape.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Functional discrepancies in HIV-specific CD8+ T-lymphocyte populations are related to plasma virus load

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Long-term cytomegalovirus infection leads to significant changes in the composition of the CD8+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

High antigen levels are the cause of T cell exhaustion during chronic viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Cytomegalovirus-specific CD4+ T cells in healthy carriers are continuously driven to replicative exhaustion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Dysfunctional CMV-specific CD8(+) T cells accumulate in the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Novel mechanism of signaling by CD28.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

The loss of telomerase activity in highly differentiated CD8+CD28-CD27- T cells is associated with decreased Akt (Ser473) phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Expansion of cytotoxic CD8+ CD28- T cells in healthy ageing people, including centenarians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

CD4+ CD7- CD28- T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Human cytomegalovirus-specific CD8(+) T-cell expansions contain long-lived cells that retain functional capacity in both young and elderly subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Susceptibility of naïve and subsets of memory T cells to apoptosis via multiple signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Central memory and effector memory T cell subsets: function, generation, and maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Gene expression characteristics of CD28null memory phenotype CD8+ T cells and its implication in T-cell aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

microRNAs and the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Microarray analysis reveals similarity between CD8+CD28- T cells from young and elderly persons, but not of CD8+CD28+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

CD28(-) T cells: their role in the age-associated decline of immune function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Evidence for microRNA-mediated regulation in rheumatic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

The capacity of the TNF family members 4-1BBL, OX40L, CD70, GITRL, CD30L and LIGHT to costimulate human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Generation and growth of CD28nullCD8+ memory T cells mediated by IL-15 and its induced cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Inflamm-aging. An evolutionary perspective on immunosenescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Vaccination in the elderly: an immunological perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Cytomegalovirus infection with interleukin-6 response predicts cardiac mortality in patients with coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Human cytomegalovirus seropositivity is associated with impaired vascular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Accelerated telomere shortening in leukocyte subpopulations of patients with coronary heart disease: role of cytomegalovirus seropositivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Human CMV infection of endothelial cells induces an angiogenic response through viral binding to EGF receptor and beta1 and beta3 integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Cytomegalovirus infection causes an increase of arterial blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Circulating cytotoxic CD8(+) CD28(-) T cells in ankylosing spondylitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Rejuvenation of the aging T cell compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Newly generated CD4 T cells in aged animals do not exhibit age-related defects in response to antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Emerging strategies to boost thymic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Mice and flies and monkeys too: caloric restriction rejuvenates the aging immune system of non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Eaten alive: a history of macroautophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Autophagy and aging: the importance of maintaining "clean" cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Autolysosomes accumulate during in vitro CD8+ T-lymphocyte aging and may participate in induced death sensitization of senescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Induction of autophagy by spermidine promotes longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Polyamine-rich food decreases age-associated pathology and mortality in aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Recent developments in yeast aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Strong dietary restrictions protect Drosophila against anoxia/reoxygenation injuries

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

mTOR regulates memory CD8 T-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Healthy Aging and Latent Infection with CMV Lead to Distinct Changes in CD8+ and CD4+ T-Cell Subsets in the Elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Changes in thymic function with age and during the treatment of HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10875-010-9499-X

Exclusive increase of CX3CR1+CD28-CD4+ T cells in inflammatory bowel disease and their recruitment as intraepithelial lymphocytes

21 January 2018

1 reference

12 December 2020

Loss of CD28 expression on CD8(+) T cells is induced by IL-2 receptor gamma chain signalling cytokines and type I IFN, and increases susceptibility to activation-induced apoptosis

1 reference

12 December 2020

No immunity for the elderly

1 reference

12 December 2020

Non-regulatory CD8+CD45RO+CD25+ T-lymphocytes may compensate for the loss of antigen-inexperienced CD8+CD45RA+ T-cells in old age

1 reference

12 December 2020

1 reference

12 December 2020

Shortened telomeres in clonally expanded CD28-CD8+ T cells imply a replicative history that is distinct from their CD28+CD8+ counterparts

1 reference

12 December 2020

Accumulation of memory T cells from childhood to old age: central and effector memory cells in CD4(+) versus effector memory and terminally differentiated memory cells in CD8(+) compartment

1 reference

12 December 2020

1 reference

12 December 2020

Altered switch in lipid composition during T-cell blast transformation in the healthy elderly

1 reference

12 December 2020

Shortage of circulating naive CD8(+) T cells provides new insights on immunodeficiency in aging

1 reference

12 December 2020

Impaired function of circulating HIV-specific CD8(+) T cells in chronic human immunodeficiency virus infection.

1 reference

12 December 2020

Thymectomy in early childhood: significant alterations of the CD4(+)CD45RA(+)CD62L(+) T cell compartment in later life

1 reference

12 December 2020

Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines

1 reference

12 December 2020

Human cytomegalovirus persistently infects aortic endothelial cells

1 reference

12 December 2020

Lack of antibody production following immunization in old age: association with CD8(+)CD28(-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines

1 reference

12 December 2020

Survival of naive CD4 T cells: roles of restricting versus selecting MHC class II and cytokine milieu

1 reference

12 December 2020

Changes in the human thymus during aging

1 reference

12 December 2020

Correlation of lymphocyte lipid composition membrane microviscosity and mitogen response in the aged

1 reference

12 December 2020

1 reference

12 December 2020

Persistent numbers of tetramer+ CD8(+) T cells, but loss of interferon-gamma+ HIV-specific T cells during progression to AIDS

1 reference

12 December 2020

Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions

1 reference

12 December 2020

Thymic involution in aging

1 reference

12 December 2020

10.1007/S10875-010-9499-X

Identifiers

DOI

1 reference

24 August 2017

1 reference