(Q37855881)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426101%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

review article

1 reference

title

Low-molecular-weight MK2 inhibitors: a tough nut to crack! (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426101%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426101%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Christine Huppertz

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426101%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

publication date

1 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426101%20AND%20SRC:MED&resulttype=core&format=json

Future Medicinal Chemistry

26 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426101%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426101%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426101%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

1243-1257

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21426101%20AND%20SRC:MED&resulttype=core&format=json

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

26 January 2020

cites work

1 reference

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

21 January 2018

1 reference

The p38 MAP kinase pathway as a therapeutic target in inflammatory disease

21 January 2018

1 reference

Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

21 January 2018

1 reference

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

21 January 2018

1 reference

MK2 and MK3--a pair of isoenzymes?

21 January 2018

1 reference

LSP1 is the major substrate for mitogen-activated protein kinase-activated protein kinase 2 in human neutrophils

21 January 2018

1 reference

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

21 January 2018

1 reference

MK2 controls the level of negative feedback in the NF-kappaB pathway and is essential for vascular permeability and airway inflammation

21 January 2018

1 reference

Reduced oxazolone-induced skin inflammation in MAPKAP kinase 2 knockout mice.

21 January 2018

1 reference

Gene deletion of MK2 inhibits TNF-alpha and IL-6 and protects against cerulein-induced pancreatitis

21 January 2018

1 reference

Systemic Deficiency of the MAP Kinase–Activated Protein Kinase 2 Reduces Atherosclerosis in Hypercholesterolemic Mice

21 January 2018

1 reference

Ischemic preconditioning involves dual cardio-protective axes with p38MAPK as upstream target

21 January 2018

1 reference

Mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 deficiency protects brain from ischemic injury in mice.

21 January 2018

1 reference

MAPKAP kinase 2-deficiency prevents neurons from cell death by reducing neuroinflammation – relevance in a mouse model of Parkinson’s disease

21 January 2018

1 reference

MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease

21 January 2018

1 reference

Distinct cellular functions of MK2.

21 January 2018

1 reference

Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2.

21 January 2018

1 reference

The p38 mitogen-activated protein kinase (MAPK) pathway in rheumatoid arthritis

21 January 2018

1 reference

The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK.

21 January 2018

1 reference

Aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2).

21 January 2018

1 reference

Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2)

21 January 2018

1 reference

Structural basis for a high affinity inhibitor bound to protein kinase MK2

21 January 2018

1 reference

Pyrrolo-pyrimidones: a novel class of MK2 inhibitors with potent cellular activity.

21 January 2018

1 reference

The discovery of carboline analogs as potent MAPKAP-K2 inhibitors

21 January 2018

1 reference

Synthesis and SAR studies of indole-based MK2 inhibitors

21 January 2018

1 reference

Identification and SAR of squarate inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)

21 January 2018

1 reference

TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

21 January 2018

1 reference

Targeting protein kinases for the development of anti-inflammatory drugs

21 January 2018

1 reference

Multiple and single binding modes of fragment-like kinase inhibitors revealed by molecular modeling, residue type-selective protonation, and nuclear overhauser effects

21 January 2018

1 reference

Specificity and mechanism of action of some commonly used protein kinase inhibitors

21 January 2018

1 reference

Rottlerin, a novel protein kinase inhibitor

21 January 2018

1 reference

Rottlerin: an inappropriate and ineffective inhibitor of PKCdelta

21 January 2018

1 reference

Meroterpenoid MAPKAP (MK2) inhibitors isolated from the indonesian marine sponge Acanthodendrilla sp.

21 January 2018

1 reference

Phaeochromycins A-E, anti-inflammatory polyketides isolated from the soil actinomycete Streptomyces phaeochromogenes LL-P018.

21 January 2018

1 reference

Catalysis and function of the p38 alpha.MK2a signaling complex

21 January 2018

1 reference

Structure of mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 suggests a bifunctional switch that couples kinase activation with nuclear export

21 January 2018

1 reference

Discovery and characterization of a substrate selective p38alpha inhibitor

21 January 2018

1 reference

Synthesis and in vivo activity of MK2 and MK2 substrate-selective p38alpha(MAPK) inhibitors in Werner syndrome cells

21 January 2018

1 reference

Nuclear export inhibitors and kinase inhibitors identified using a MAPK-activated protein kinase 2 redistribution screen

21 January 2018

1 reference

Molecular basis of MAPK-activated protein kinase 2:p38 assembly

21 January 2018

1 reference

Crystal structure of the p38 alpha-MAPKAP kinase 2 heterodimer

21 January 2018

1 reference

Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme

21 January 2018

1 reference

Inhibition of p38: has the fat lady sung?

21 January 2018

1 reference

Targeting innate immunity protein kinase signalling in inflammation

21 January 2018

1 reference