(Q37856375)

24 August 2017

1 reference

title

Occupational hazards: allosteric regulation of protein kinases through the nucleotide-binding pocket (English)

1 reference

24 August 2017

1 reference

Angus J M Cameron

1

1 reference

24 August 2017

publication date

1 April 2011

1 reference

Biochemical Society Transactions

24 August 2017

published in

1 reference

24 August 2017

volume

39

1 reference

24 August 2017

issue

2

1 reference

24 August 2017

page(s)

472-476

1 reference

The protein kinase complement of the human genome

24 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Evolution of protein kinase signaling from yeast to man

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Did protein kinase regulatory mechanisms evolve through elaboration of a simple structural component?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Protein kinases: evolution of dynamic regulatory proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Multiple pathways control protein kinase C phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

PDK1, the master regulator of AGC kinase signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

TOR regulation of AGC kinases in yeast and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

The nuts and bolts of AGC protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

The identification and characterization of novel PKCepsilon phosphorylation sites provide evidence for functional cross-talk within the PKC superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Dephosphorylation of PKCdelta by protein phosphatase 2Ac and its inhibition by nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Inhibitor hijacking of Akt activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Allosteric activation of the protein kinase PDK1 with low molecular weight compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Mutations of the BRAF gene in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

The RAF proteins take centre stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Paradoxical activation of Raf by a novel Raf inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Raf-1 is activated by the p38 mitogen-activated protein kinase inhibitor, SB203580.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Design of allele-specific inhibitors to probe protein kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

A chemical switch for inhibitor-sensitive alleles of any protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Bypassing a Kinase Activity with an ATP-Competitive Drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Tyrosine kinase inhibitors: why does the current process of clinical development not apply to them?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Discovery of a small-molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFR , Kit, and Src kinases: novel type II inhibitor of gatekeeper mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

ATP and MO25α Regulate the Conformational State of the STRADα Pseudokinase and Activation of the LKB1 Tumour Suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

The conformational plasticity of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390472

21 January 2018

Identifiers

DOI

10.1042/BST0390472

1 reference

24 August 2017

1 reference