(Q37863124)

24 August 2017

1 reference

title

Mitochondrion: an emerging platform critical for host antiviral signaling (English)

1 reference

24 August 2017

1 reference

Chen Wang

1

1 reference

24 August 2017

Xinyi Liu

series ordinal

2

1 reference

24 August 2017

Bo Wei

series ordinal

3

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24 August 2017

language of work or name

English

0 references

publication date

26 February 2011

1 reference

Expert Opinion on Therapeutic Targets

24 August 2017

1 reference

24 August 2017

15

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24 August 2017

5

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24 August 2017

647-665

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An ecological and evolutionary perspective on human-microbe mutualism and disease

24 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Recognition of microorganisms and activation of the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Decoding the patterns of self and nonself by the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Viral evasion and subversion of pattern-recognition receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Viruses and interferon: a fight for supremacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

IFI16 is an innate immune sensor for intracellular DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Regulation of mitochondrial antiviral signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

MDA5/RIG-I and virus recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Structural mechanism of RNA recognition by the RIG-I-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

VISA is an adapter protein required for virus-triggered IFN-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Tom70 mediates activation of interferon regulatory factor 3 on mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

TRAF5 is a downstream target of MAVS in antiviral innate immune signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

21 January 2018

Mitochondrial evolution

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Mitochondria: more than just a powerhouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Ubiquitin-regulated recruitment of IkappaB kinase epsilon to the MAVS interferon signaling adapter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Hsp90 regulates activation of interferon regulatory factor 3 and TBK-1 stabilization in Sendai virus-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Translocation of proteins into mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Crystal structure of yeast mitochondrial outer membrane translocon member Tom70p.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The Hsp90 molecular chaperone: an open and shut case for treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

MAVS self-association mediates antiviral innate immune signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

MAVS dimer is a crucial signaling component of innate immunity and the target of hepatitis C virus NS3/4A protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Interferon-inducible antiviral effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

RNA- and virus-independent inhibition of antiviral signaling by RNA helicase LGP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

NLRX1 is a regulator of mitochondrial antiviral immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

NLRC5 deficiency does not influence cytokine induction by virus and bacteria infections.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Mitofusin 2 inhibits mitochondrial antiviral signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Virus-infection or 5'ppp-RNA activates antiviral signal through redistribution of IPS-1 mediated by MFN1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The Atg5 Atg12 conjugate associates with innate antiviral immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Peroxisomes are signaling platforms for antiviral innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

c-Abl tyrosine kinase interacts with MAVS and regulates innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The tyrosine kinase c-Src enhances RIG-I (retinoic acid-inducible gene I)-elicited antiviral signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Identification of loss of function mutations in human genes encoding RIG-I and MDA5: implications for resistance to type I diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

REUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid-inducible gene-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

UbcH8 regulates ubiquitin and ISG15 conjugation to RIG-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

DUBA: a deubiquitinase that regulates type I interferon production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

A20 is a negative regulator of IFN regulatory factor 3 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Negative regulation of MAVS-mediated innate immune response by PSMA7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Negative feedback regulation of RIG-I-mediated antiviral signaling by interferon-induced ISG15 conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Emerging role of ISG15 in antiviral immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

SUMOylation of RIG-I positively regulates the type I interferon signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Virus infection triggers SUMOylation of IRF3 and IRF7, leading to the negative regulation of type I interferon gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Mitochondrial formation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

NOX enzymes and the biology of reactive oxygen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Antimicrobial reactive oxygen and nitrogen species: concepts and controversies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Phosphorylation-mediated negative regulation of RIG-I antiviral activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVS

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The antiviral adaptor proteins Cardif and Trif are processed and inactivated by caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Double-stranded RNA binding of influenza B virus nonstructural NS1 protein inhibits protein kinase R but is not essential to antagonize production of alpha/beta interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Influenza A virus polymerase inhibits type I interferon induction by binding to interferon beta promoter stimulator 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Hepatitis B virus X protein suppresses virus-triggered IRF3 activation and IFN-beta induction by disrupting the VISA-associated complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKepsilo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Murine gamma-herpesvirus 68 hijacks MAVS and IKKbeta to initiate lytic replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Viral apoptosis is induced by IRF-3-mediated activation of Bax

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

MAVS-mediated apoptosis and its inhibition by viral proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Tom70 imports antiviral immunity to the mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Double-stranded DNA and double-stranded RNA induce a common antiviral signaling pathway in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The danger model: a renewed sense of self

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

The danger model in deciphering autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Trex1 prevents cell-intrinsic initiation of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Mutation of DNASE1 in people with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2011.561321

10.1517/14728222.2011.561321

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference