(Q37879217)

24 August 2017

1 reference

title

Translocator protein (18 kDa) as a target for novel anxiolytics with a favourable side-effect profile (English)

1 reference

24 August 2017

author

Vasilios Papadopoulos

6

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24 August 2017

C Nothdurfter

1

1 reference

24 August 2017

G Rammes

2

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24 August 2017

T C Baghai

3

1 reference

24 August 2017

C Schüle

4

1 reference

24 August 2017

M Schumacher

5

1 reference

24 August 2017

R Rupprecht

7

1 reference

24 August 2017

publication date

1 January 2012

1 reference

Journal of Neuroendocrinology

24 August 2017

published in

1 reference

24 August 2017

volume

24

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24 August 2017

issue

1

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24 August 2017

page(s)

82-92

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Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication

24 August 2017

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Induced panic attacks shift gamma-aminobutyric acid type A receptor modulatory neuroactive steroid composition in patients with panic disorder: preliminary results

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Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function

21 January 2018

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Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier

21 January 2018

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VDAC activation by the 18 kDa translocator protein (TSPO), implications for apoptosis

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Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis

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Cholesterol transport in steroid biosynthesis: role of protein-protein interactions and implications in disease states.

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Peripheral-type benzodiazepine receptor: structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis

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Phase-dependent roles of reactive microglia and astrocytes in nervous system injury as delineated by imaging of peripheral benzodiazepine receptor

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Differential regulation of ‘central’ and ‘peripheral’ benzodiazepine binding sites in the rat olfactory bulb

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Peripheral benzodiazepine receptor (PBR) new insight in cell proliferation and cell differentiation review.

21 January 2018

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Channel-like functions of the 18-kDa translocator protein (TSPO): regulation of apoptosis and steroidogenesis as part of the host-defense response

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Identification of des-(Gly-Ile)-endozepine as an effector of corticotropin-dependent adrenal steroidogenesis: stimulation of cholesterol delivery is mediated by the peripheral benzodiazepine receptor

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Neurosteroid metabolism in the human brain

21 January 2018

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Diazepam Binding Inhibitor and Its Processing Products Stimulate Mitochondrial Steroid Biosynthesis via an Interaction with Mitochondrial Benzodiazepine Receptors*

21 January 2018

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Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: regulation by a mitochondrial diazepam binding inhibitor receptor

21 January 2018

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Is there a mitochondrial signaling complex facilitating cholesterol import?

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Activation of peripheral mitochondrial benzodiazepine receptors in the hippocampus stimulates allopregnanolone synthesis and produces anxiolytic-like effects in the rat.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Stimulation of brain pregnenolone synthesis by mitochondrial diazepam binding inhibitor receptor ligands in vivo

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

2-Phenyl-imidazo[1,2-a]pyridine derivatives as ligands for peripheral benzodiazepine receptors: stimulation of neurosteroid synthesis and anticonflict action in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

The anxiolytic etifoxine activates the peripheral benzodiazepine receptor and increases the neurosteroid levels in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Effects of antidepressant treatment on neuroactive steroids in major depression

21 January 2018

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Relevance of endogenous 3alpha-reduced neurosteroids to depression and antidepressant action

21 January 2018

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Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes

21 January 2018

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Neuroactive steroid regulation of neurotransmitter release in the CNS: action, mechanism and possible significance

21 January 2018

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Neurosteroids: endogenous allosteric modulators of GABA(A) receptors.

21 January 2018

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Progesterone 5-alpha-reduction in neuronal and in different types of glial cell cultures: type 1 and 2 astrocytes and oligodendrocytes

21 January 2018

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The 5alpha-reductase in the central nervous system: expression and modes of control

21 January 2018

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Topography and function of androgen-metabolizing enzymes in the central nervous system

21 January 2018

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Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis

21 January 2018

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The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging

21 January 2018

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Effects on free radical generation by ligands of the peripheral benzodiazepine receptor in cultured neural cells

21 January 2018

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Etifoxine improves peripheral nerve regeneration and functional recovery

21 January 2018

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Extrasynaptic GABAA receptors of thalamocortical neurons: a molecular target for hypnotics.

21 January 2018

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Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

GABAA receptor alpha 4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Formation and plasticity of GABAergic synapses: physiological mechanisms and pathophysiological implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Which GABA(A) receptor subunits are necessary for tonic inhibition in the hippocampus?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

The expression of GABAA beta subunit isoforms in synaptic and extrasynaptic receptor populations of mouse dentate gyrus granule cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Extrasynaptic alphabeta subunit GABAA receptors on rat hippocampal pyramidal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Intact synaptic GABAergic inhibition and altered neurosteroid modulation of thalamic relay neurons in mice lacking delta subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Novel compounds selectively enhance delta subunit containing GABA A receptors and increase tonic currents in thalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Input-dependent synaptic targeting of alpha(2)-subunit-containing GABA(A) receptors in synapses of hippocampal pyramidal cells of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Stress, anxiety and peripheral benzodiazepine receptor mRNA levels in human lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Peripheral benzodiazepine receptor messenger RNA is decreased in lymphocytes of generalized anxiety disorder patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Platelet 18 kDa Translocator Protein density is reduced in depressed patients with adult separation anxiety.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Altered platelet peripheral-type benzodiazepine receptor in posttraumatic stress disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Peripheral-type benzodiazepine receptors on platelets are correlated with the degrees of anxiety in normal human subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Decreased platelet peripheral-type benzodiazepine receptors in persistently violent schizophrenia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Decreased platelet peripheral-type benzodiazepine receptors in adolescent inpatients with repeated suicide attempts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Evidence that variation in the peripheral benzodiazepine receptor (PBR) gene influences susceptibility to panic disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Peripheral benzodiazepine receptors in patients with chronic schizophrenia: a PET study with [11C]DAA1106.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Cholesterol binding at the cholesterol recognition/ interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Mapping and fitting the peripheral benzodiazepine receptor binding site by carboxamide derivatives. Comparison of different approaches to quantitative ligand-receptor interaction modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Porphyrins are endogenous ligands for the mitochondrial (peripheral-type) benzodiazepine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Diazepam binding inhibitor (DBI): a peptide with multiple biological actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Acyl-coenzyme A binding domain containing 3 (ACBD3; PAP7; GCP60): an emerging signaling molecule.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Cerebrospinal fluid levels of diazepam-binding inhibitor in neurodegenerative disorders with dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Beta-amyloid peptide stimulates endozepine release in cultured rat astrocytes through activation of N-formyl peptide receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Midazolam inhibits hippocampal long-term potentiation and learning through dual central and peripheral benzodiazepine receptor activation and neurosteroidogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Efficacy of etifoxine compared to lorazepam monotherapy in the treatment of patients with adjustment disorders with anxiety: a double-blind controlled study in general practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Modulation of GABAergic synaptic transmission by the non-benzodiazepine anxiolytic etifoxine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Lack of tolerance to anxiolysis and withdrawal symptoms in mice repeatedly treated with AC-5216, a selective TSPO ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Structure-function of human 3 alpha-hydroxysteroid dehydrogenases: genes and proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Neurosteroids: endogenous regulators of the GABA(A) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Subunit dependent modulation of GABAA receptor function by neuroactive steroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

The influence of subunit composition on the interaction of neurosteroids with GABA(A) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Axonal injury-dependent induction of the peripheral benzodiazepine receptor in small-diameter adult rat primary sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Role of the peripheral benzodiazepine receptor in sensory neuron regeneration

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Visualising microglial activation in vivo

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Evidence in favour of a role for peripheral-type benzodiazepine receptor ligands in amplification of neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Peripheral benzodiazepine receptor imaging in CNS demyelination: functional implications of anatomical and cellular localization

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Translocator protein (18 kDa) TSPO: an emerging therapeutic target in neurotrauma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Increased peripheral benzodiazepine binding sites and pentraxin 3 expression in the spinal cord during EAE: relation to inflammatory cytokines and modulation by dexamethasone and rolipram

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Abnormal peripheral benzodiazepine receptor density associated with generalized social phobia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Acyl-CoA binding proteins; structural and functional conservation over 2000 MYA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Peripheral-type benzodiazepine receptor binding sites in platelets of patients with panic disorder associated to separation anxiety symptoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

Reductions in Platelet 18-kDa Translocator Protein Density Are Associated with Adult Separation Anxiety in Patients with Bipolar Disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2826.2011.02166.X

10.1111/J.1365-2826.2011.02166.X

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference