(Q37890201)

24 August 2017

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title

Evolution of leptin structure and function (English)

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24 August 2017

Robert J Denver

1

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24 August 2017

Ronald M Bonett

series ordinal

2

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24 August 2017

Graham C Boorse

series ordinal

3

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24 August 2017

publication date

16 June 2011

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24 August 2017

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24 August 2017

volume

94

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24 August 2017

issue

1

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24 August 2017

page(s)

21-38

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A historical perspective on leptin.

24 August 2017

cites work

1 reference

Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

21 January 2018

1 reference

Positional cloning of the mouse obese gene and its human homologue

21 January 2018

1 reference

Phylogeny and evolution of class-I helical cytokines.

21 January 2018

1 reference

Identification and expression cloning of a leptin receptor, OB-R

21 January 2018

1 reference

Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

21 January 2018

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Abnormal splicing of the leptin receptor in diabetic mice

21 January 2018

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Effects of the obese gene product on body weight regulation in ob/ob mice

21 January 2018

1 reference

Central actions of adipocyte hormones

21 January 2018

1 reference

Leptin and mTOR: partners in metabolism and inflammation

21 January 2018

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Determinants of brown adipocyte development and thermogenesis

21 January 2018

1 reference

Modern science versus the stigma of obesity

21 January 2018

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A war on obesity, not the obese.

21 January 2018

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Is obesity our genetic legacy?

21 January 2018

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Obesity and leptin resistance: distinguishing cause from effect

21 January 2018

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Leptin regulation of neuroendocrine systems

21 January 2018

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Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis

21 January 2018

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Leptin sensitive neurons in the hypothalamus

21 January 2018

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Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei.

21 January 2018

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Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area.

21 January 2018

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The role of leptin receptor signaling in feeding and neuroendocrine function

21 January 2018

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LRb signals act within a distributed network of leptin-responsive neurones to mediate leptin action

21 January 2018

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Neuropeptides and the control of food intake in fish.

21 January 2018

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Roles of stress hormones in food intake regulation in anuran amphibians throughout the life cycle

21 January 2018

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Stress, neuropeptides, and feeding behavior: a comparative perspective

21 January 2018

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Leptin (ob gene) of the South African clawed frog Xenopus laevis

21 January 2018

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Production of recombinant leptin and its effects on food intake in rainbow trout (Oncorhynchus mykiss).

21 January 2018

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Gene structure, recombinant expression and functional characterization of grass carp leptin

21 January 2018

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Leptin and regulation of linear growth

21 January 2018

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Energy balance and puberty onset: emerging role of central mTOR signaling

21 January 2018

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A role for leptin in brain development

21 January 2018

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The role of leptin in the development of the cerebral cortex in mouse embryos

21 January 2018

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Roles of leptin in prenatal and perinatal brain development

21 January 2018

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Development of leptin-sensitive circuits.

21 January 2018

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Leptin is a potent stimulator of bone growth in ob/ob mice

21 January 2018

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Hypothalamic regulation of bone

21 January 2018

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The central regulation of bone mass, the first link between bone remodeling and energy metabolism

21 January 2018

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An evolving integrative physiology: skeleton and energy metabolism

21 January 2018

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The role of leptin in the respiratory system: an overview

21 January 2018

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Three questions about leptin and immunity

21 January 2018

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Leptin signaling: A key pathway in immune responses.

21 January 2018

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Regulation of thyrotropin-releasing hormone-expressing neurons in paraventricular nucleus of the hypothalamus by signals of adiposity

21 January 2018

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Molecular evolution of leptin

21 January 2018

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Molecular cloning and expression of leptin in gray and harbor seal blubber, bone marrow, and lung and its potential role in marine mammal respiratory physiology

21 January 2018

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Natural selection and adaptive evolution of leptin in the ochotona family driven by the cold environmental stress

21 January 2018

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Cloning the chicken leptin gene.

21 January 2018

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Chicken genomics resource: sequencing and annotation of 35,407 ESTs from single and multiple tissue cDNA libraries and CAP3 assembly of a chicken gene index

21 January 2018

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The chicken leptin gene: has it been cloned?

21 January 2018

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Increased leptin expression in common Carp (Cyprinus carpio) after food intake but not after fasting or feeding to satiation

21 January 2018

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Monitoring leptin activity using the chicken leptin receptor

21 January 2018

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Identification of cDNA coding for a homologue to mammalian leptin from pufferfish, Takifugu rubripes

21 January 2018

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Identification of a non-mammalian leptin-like gene: characterization and expression in the tiger salamander (Ambystoma tigrinum).

21 January 2018

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Two divergent leptin paralogues in zebrafish (Danio rerio) that originate early in teleostean evolution.

21 January 2018

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Leptin and leptin receptor genes in Atlantic salmon: Cloning, phylogeny, tissue distribution and expression correlated to long-term feeding status.

21 January 2018

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Leptin and ghrelin in anadromous Arctic charr: cloning and change in expressions during a seasonal feeding cycle

21 January 2018

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Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype

21 January 2018

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Chromosome evolution in the Salmonidae (Pisces): an update

21 January 2018

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Genomic characterization of multiple leptin genes and a leptin receptor gene in the Japanese medaka, Oryzias latipes

21 January 2018

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Molecular genetic aspects of tetraploidy in the common carp Cyprinus carpio.

21 January 2018

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Recent duplication of the common carp (Cyprinus carpio L.) genome as revealed by analyses of microsatellite loci.

21 January 2018

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Effects of leptin administration on the endocrine pancreas and liver in the lizard Podarcis sicula

21 January 2018

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Seasonal effects on circulating leptin in the lizard Sceloporus undulatus from two populations.

21 January 2018

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Localization and role of leptin in the thyroid gland of the lizard Podarcis sicula (Reptilia, Lacertidae).

21 January 2018

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Immunocytochemical detection of leptin in non-mammalian vertebrate stomach.

21 January 2018

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Leptin presence in plasma, liver and fat bodies in the lizard Podarcis sicula: fluctuations throughout the reproductive cycle.

21 January 2018

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Evidence for leptin expression in fishes

21 January 2018

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Purification and characterization of recombinant pufferfish (Takifugu rubripes) leptin

21 January 2018

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Structure-function studies of human leptin

21 January 2018

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Mapping of the leptin binding sites and design of a leptin antagonist

21 January 2018

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Development of leptin antagonists and their potential use in experimental biology and medicine

21 January 2018

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Pegylated leptin antagonist is a potent orexigenic agent: preparation and mechanism of activity

21 January 2018

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Mapping of binding site III in the leptin receptor and modeling of a hexameric leptin.leptin receptor complex

21 January 2018

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The stomach is a source of leptin

21 January 2018

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Leptin receptor-mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat.

21 January 2018

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The human obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic, and genetic maps of chromosome 7.

21 January 2018

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Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta

21 January 2018

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A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

21 January 2018

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The role of the leptin in reproduction

21 January 2018

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Leptin stimulates pituitary prolactin release through an extracellular signal-regulated kinase-dependent pathway

21 January 2018

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Leptin: a multifaceted hormone in the central nervous system.

21 January 2018

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Trophic action of leptin on hypothalamic neurons that regulate feeding

21 January 2018

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Minireview: Leptin and development of hypothalamic feeding circuits.

21 January 2018

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Leptin: a potential cognitive enhancer?

21 January 2018

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Evolution of Class I cytokine receptors

21 January 2018

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Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease.

21 January 2018

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Leptin receptor signaling and the regulation of mammalian physiology

21 January 2018

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Molecular cloning and tissue distribution of a short form chicken leptin receptor mRNA.

21 January 2018

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Regulation of Jak kinases by intracellular leptin receptor sequences.

21 January 2018

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Gp130 and the interleukin-6 family of cytokines

21 January 2018

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Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

21 January 2018

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Activation of downstream signals by the long form of the leptin receptor

21 January 2018

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Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor

21 January 2018

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Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction

21 January 2018

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SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985

21 January 2018

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The long form of the leptin receptor regulates STAT5 and ribosomal protein S6 via alternate mechanisms

21 January 2018

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Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis

21 January 2018

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Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.

21 January 2018

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Leptin secretion and leptin receptor in the human stomach

21 January 2018

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The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.

21 January 2018

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Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

21 January 2018

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Selective deletion of leptin receptor in neurons leads to obesity

21 January 2018

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Expression of leptin receptor gene in developing and adult zebrafish

21 January 2018

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Appetite regulation: from the gut to the hypothalamus

21 January 2018

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The neuroendocrinology and neuroscience of energy balance

21 January 2018

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Leptin activation in hypothalamus.

21 January 2018

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Chicken leptin: properties and actions.

21 January 2018

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Intracerebroventricular administration of mouse leptin does not reduce food intake in the chicken.

21 January 2018

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Role of leptin in the control of feeding of goldfish Carassius auratus: interactions with cholecystokinin, neuropeptide Y and orexin A, and modulation by fasting.

21 January 2018

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Leptin reduces Atlantic salmon growth through the central pro-opiomelanocortin pathway.

21 January 2018

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Leptin and the regulation of body weight in mammals

21 January 2018

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The function of leptin in nutrition, weight, and physiology

21 January 2018

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A homologous salmonid leptin radioimmunoassay indicates elevated plasma leptin levels during fasting of rainbow trout

21 January 2018

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Metabolic signals in human puberty: effects of over and undernutrition

21 January 2018

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Fetal undernutrition and disease in later life

21 January 2018

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Early influences on human energy regulation: thrifty genotypes and thrifty phenotypes

21 January 2018

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Early origins of obesity: programming the appetite regulatory system

21 January 2018

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Regulation of leptin synthesis and secretion before birth: implications for the early programming of adult obesity.

21 January 2018

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Perinatal environment and its influences on metabolic programming of offspring

21 January 2018

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Spatial and developmental regulation of leptin in fetal sheep

21 January 2018

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Crystal structure of the obese protein leptin-E100

21 January 2018

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Is there a leptin gene in the chicken genome? Lessons from phylogenetics, bioinformatics and genomics

21 January 2018

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Immunolocalisation of leptin in the digestive system of juvenile European sea bass (Dicentrarchus labrax)

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000328435

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24 August 2017

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