(Q37896025)

English

Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling?: Neuronal life, growth and death signalling are crucially regulated by intra-membrane proteolysis and trafficking of p75(NTR).

scientific article published on 30 June 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 August 2017

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Europe PubMed Central

Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling?: Neuronal life, growth and death signalling are crucially regulated by intra-membrane proteolysis and trafficking of p75(NTR). (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

1 reference

based on heuristic

inferred from title

3

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

object named as

Dusan Matusica

2

0 references

Elizabeth J. Coulson

object named as

Elizabeth J Coulson

4

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author name string

Sune Skeldal

1

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Europe PubMed Central

PubMed publication ID

25 August 2017

language of work or name

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publication date

30 June 2011

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Europe PubMed Central

PubMed publication ID

25 August 2017

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Europe PubMed Central

PubMed publication ID

25 August 2017

33

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Europe PubMed Central

PubMed publication ID

25 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

614-625

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

Nerve growth factor: two receptors, multiple functions

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Structural determinants of neurotrophin action.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Neurotrophins: roles in neuronal development and function

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

The neurotrophic hypothesis: where does it stand?

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

A model for neuronal competition during development

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

The p75 neurotrophin receptor in human development and disease.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

NMR structure of the death domain of the p75 neurotrophin receptor

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Neurotrophin signaling through the p75 neurotrophin receptor

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Chopper, a New Death Domain of the p75 Neurotrophin Receptor That Mediates Rapid Neuronal Cell Death

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Palmitoylation of the C-terminal fragment of p75(NTR) regulates death signaling and is required for subsequent cleavage by gamma-secretase

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Molecular and Structural Insight into proNGF Engagement of p75NTR and Sortilin

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Structure of nerve growth factor complexed with the shared neurotrophin receptor p75

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Receptor recognition by gp130 cytokines

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Nuclear translocation of the p75 neurotrophin receptor cytoplasmic domain in response to neurotrophin binding

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal gamma-secretase-mediated release of the p75 intracellular domain.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

p75 neurotrophin receptor mediates neuronal cell death by activating GIRK channels through phosphatidylinositol 4,5-bisphosphate.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

The p75NTR intracellular domain generated by neurotrophin-induced receptor cleavage potentiates Trk signaling

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Trk-dependent ADAM17 activation facilitates neurotrophin survival signaling.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

A pro-apoptotic fragment of the p75 neurotrophin receptor is expressed in p75NTRExonIV null mice.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Neurotrophins and their receptors: a convergence point for many signalling pathways

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Neurotrophin-regulated signalling pathways

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Neurotrophin signal transduction by the Trk receptor

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Nerve growth factor mediates signal transduction through trk homodimer receptors

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

A novel p75 neurotrophin receptor-related protein, NRH2, regulates nerve growth factor binding to the TrkA receptor.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Early events in neurotrophin signalling via Trk and p75 receptors

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Sortilin is essential for proNGF-induced neuronal cell death

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Grasping objects: the cortical mechanisms of visuomotor transformation

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Multi-tasking by the p75 neurotrophin receptor: sortilin things out?

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

p75NTR is positively promiscuous: novel partners and new insights

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

ProNGF mediates death of Natural Killer cells through activation of the p75NTR-sortilin complex.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

High-resolution fractionation of signaling endosomes containing different receptors

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Biological activity of nerve growth factor precursor is dependent upon relative levels of its receptors

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Enhanced protein expressions of sortilin and p75NTR in retina of rat following elevated intraocular pressure-induced retinal ischemia

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Age-dependent alterations in nerve growth factor (NGF)-related proteins, sortilin, and learning and memory in rats

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Cholinergic system during the progression of Alzheimer's disease: therapeutic implications

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Endosomal transport of neurotrophins: roles in signaling and neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-alpha-converting enzyme/ADAM17.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Beta-amyloid(1-42) induces neuronal death through the p75 neurotrophin receptor.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Induction of apoptosis by the low-affinity NGF receptor

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

The role of neurotransmission and the Chopper domain in p75 neurotrophin receptor death signaling

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

p75(NTR)-immunoreactivity in the subventricular zone of adult male rats: expression by cycling cells.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

p75 neurotrophin receptor expression defines a population of BDNF-responsive neurogenic precursor cells

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

The p75 neurotrophin receptor is expressed by adult mouse dentate progenitor cells and regulates neuronal and non-neuronal cell genesis

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

A common neural progenitor for the CNS and PNS.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Expression analysis of a novel p75(NTR) signaling protein, which regulates cell cycle progression and apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Bex1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycle

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Abeta(1-42) stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Gamma-secretase represents a therapeutic target for the treatment of invasive glioma mediated by the p75 neurotrophin receptor

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

p75NTR-dependent, myelin-mediated axonal degeneration regulates neural connectivity in the adult brain

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

NRAGE and the cycling side of the neurotrophin receptor p75.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

The p75(NTR) tumor suppressor induces cell cycle arrest facilitating caspase mediated apoptosis in prostate tumor cells

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

A novel hypothesis for Alzheimer disease based on neuronal tetraploidy induced by p75 (NTR).

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Somatic tetraploidy in specific chick retinal ganglion cells induced by nerve growth factor

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

PKA phosphorylates the p75 receptor and regulates its localization to lipid rafts

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

The tyrosine kinase Fyn determines the localization of TrkB receptors in lipid rafts.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Caveosomes and endocytosis of lipid rafts

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Grit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter molecules

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75NTR.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

A switch in retrograde signaling from survival to stress in rapid-onset neurodegeneration

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Nuclear localization of the p75 neurotrophin receptor intracellular domain

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

NRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell death

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100036

21 January 2018

Identifiers

10.1002/BIES.201100036

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

ResearchGate publication ID

0 references

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