(Q37946957)

25 August 2017

title

Pharmacogenomics and epilepsy: the road ahead (English)

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25 August 2017

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Mark McCormack

2

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Gianpiero L. Cavalleri

object named as

Gianpiero L Cavalleri

1

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author name string

Saud Alhusaini

3

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25 August 2017

Elijah Chaila

4

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25 August 2017

Norman Delanty

5

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25 August 2017

publication date

1 October 2011

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25 August 2017

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25 August 2017

volume

12

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25 August 2017

issue

10

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25 August 2017

page(s)

1429-1447

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Socioeconomic variation in incidence of epilepsy: prospective community based study in south east England

25 August 2017

cites work

1 reference

The epidemiology of epilepsy revisited

21 January 2018

1 reference

The descriptive epidemiology of epilepsy-a review

21 January 2018

1 reference

Management of epilepsy in adolescents and adults.

21 January 2018

1 reference

The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial

21 January 2018

1 reference

The Irish epilepsy surgery experience: Long-term follow-up.

21 January 2018

1 reference

Failure to replicate previously reported genetic associations with sporadic temporal lobe epilepsy: where to from here?

21 January 2018

1 reference

Genetic association studies in epilepsy: "the truth is out there".

21 January 2018

1 reference

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

21 January 2018

1 reference

Finding the missing heritability of complex diseases

21 January 2018

1 reference

Rare variants create synthetic genome-wide associations

21 January 2018

1 reference

Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review

21 January 2018

1 reference

Synthetic associations are unlikely to account for many common disease genome-wide association signals

21 January 2018

1 reference

Synthetic associations created by rare variants do not explain most GWAS results

21 January 2018

1 reference

ABC transporters during epilepsy and mechanisms underlying multidrug resistance in refractory epilepsy

21 January 2018

1 reference

Epilepsy pharmacogenetics

21 January 2018

1 reference

Polymorphism of the MDR1/ABCB1 C3435T drug-transporter and resistance to anticonvulsant drugs: a meta-analysis

21 January 2018

1 reference

Association of ABCB1 gene polymorphisms and their haplotypes with response to antiepileptic drugs: a systematic review and meta-analysis

21 January 2018

1 reference

Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response.

21 January 2018

1 reference

Functional evaluation of polymorphisms in the human ABCB1 gene and the impact on clinical responses of antiepileptic drugs

21 January 2018

1 reference

Non-response to antiepileptic pharmacotherapy is associated with the ABCC2 -24C>T polymorphism in young and adult patients with epilepsy.

21 January 2018

1 reference

Refractory seizures: try additional antiepileptic drugs (after two have failed) or go directly to early surgery evaluation?

21 January 2018

1 reference

Response to first drug trial predicts outcome in childhood temporal lobe epilepsy

21 January 2018

1 reference

Early development of intractable epilepsy in children: a prospective study

21 January 2018

1 reference

Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies

21 January 2018

1 reference

The antiepileptic drug topiramate is a substrate for human P-glycoprotein but not multidrug resistance proteins

21 January 2018

1 reference

Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein

21 January 2018

1 reference

Several major antiepileptic drugs are substrates for human P-glycoprotein

21 January 2018

1 reference

Development of a humanized in vitro blood-brain barrier model to screen for brain penetration of antiepileptic drugs

21 January 2018

1 reference

Genetic factors associated with drug-resistance of epilepsy: relevance of stratification by patient age and aetiology of epilepsy

21 January 2018

1 reference

Multi-SNP pharmacogenomic classifier is superior to single-SNP models for predicting drug outcome in complex diseases

21 January 2018

1 reference

De novo mutations in the sodium-channel gene SCN1A cause severe myoclonic epilepsy of infancy

21 January 2018

1 reference

The pharmacologic treatment of Dravet syndrome

21 January 2018

1 reference

Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

21 January 2018

1 reference

Altered function of the SCN1A voltage-gated sodium channel leads to gamma-aminobutyric acid-ergic (GABAergic) interneuron abnormalities

21 January 2018

1 reference

Debate: Does genetic information in humans help us treat patients? PRO--genetic information in humans helps us treat patients. CON--genetic information does not help at all.

21 January 2018

1 reference

Dravet syndrome or genetic (generalized) epilepsy with febrile seizures plus?

21 January 2018

1 reference

A prospective analysis of the outcome of levetiracetam in clinical practice

21 January 2018

1 reference

Association between SCN1A polymorphism and carbamazepine-resistant epilepsy

21 January 2018

1 reference

No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy.

21 January 2018

1 reference

Genetic polymorphisms in sex hormone metabolizing genes and drug response in women with epilepsy.

21 January 2018

1 reference

The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement

21 January 2018

1 reference

A common genetic basis for idiosyncratic toxicity of warfarin and phenytoin.

21 January 2018

1 reference

Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin

21 January 2018

1 reference

Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms

21 January 2018

1 reference

CYP2C9, CYP2C19, ABCB1 (MDR1) genetic polymorphisms and phenytoin metabolism in a Black Beninese population

21 January 2018

1 reference

Paradoxical urinary phenytoin metabolite (S)/(R) ratios in CYP2C19*1/*2 patients.

21 January 2018

1 reference

Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin

21 January 2018

1 reference

CYP2C9*1B promoter polymorphisms, in linkage with CYP2C19*2, affect phenytoin autoinduction of clearance and maintenance dose

21 January 2018

1 reference

Carbamazepine: a 'blind' assessment of CVP-associated metabolism and interactions in human liver-derived in vitro systems

21 January 2018

1 reference

Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients.

21 January 2018

1 reference

Genetic variants in microsomal epoxide hydrolase influence carbamazepine dosing.

21 January 2018

1 reference

Nova2 interacts with a cis-acting polymorphism to influence the proportions of drug-responsive splice variants of SCN1A.

21 January 2018

1 reference

A functional polymorphism in the SCN1A gene is not associated with carbamazepine dosages in Austrian patients with epilepsy

21 January 2018

1 reference

Severe phenytoin toxicity in a CYP2C9*3*3 homozygous mutant from India

21 January 2018

1 reference

Severe intoxication after phenytoin infusion: a preventable pharmacogenetic adverse reaction.

21 January 2018

1 reference

Phenytoin toxicity due to genetic polymorphism

21 January 2018

1 reference

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on phenytoin-induced neurological toxicity in Indian epileptic patients

21 January 2018

1 reference

Severe persistent visual field constriction associated with vigabatrin

21 January 2018

1 reference

Vigabatrin: a comprehensive review of drug properties including clinical updates following recent FDA approval

21 January 2018

1 reference

Visual function is stable in patients who continue long-term vigabatrin therapy: implications for clinical decision making

21 January 2018

1 reference

Visual field severity indices demonstrate dose-dependent visual loss from vigabatrin therapy

21 January 2018

1 reference

Visual field loss in patients with refractory partial epilepsy treated with vigabatrin: final results from an open-label, observational, multicentre study

21 January 2018

1 reference

Comparison and predictors of rash associated with 15 antiepileptic drugs

21 January 2018

1 reference

Carbamazepine-induced acute liver failure as part of the DRESS syndrome.

21 January 2018

1 reference

Toxic epidermal necrolysis and Stevens-Johnson syndrome

21 January 2018

1 reference

Medical genetics: a marker for Stevens-Johnson syndrome

21 January 2018

1 reference

Cutaneous adverse drug reactions seen in a tertiary hospital in Johor, Malaysia.

21 January 2018

1 reference

Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with HLA-B*1502 allele in Thai population.

21 January 2018

1 reference

A European study of HLA-B in Stevens-Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugs

21 January 2018

1 reference

HLA-B locus in Caucasian patients with carbamazepine hypersensitivity

21 January 2018

1 reference

Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese

21 January 2018

1 reference

Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese

21 January 2018

1 reference

Association study of lamotrigine-induced cutaneous adverse reactions and HLA-B*1502 in a Han Chinese population

21 January 2018

1 reference

Oxcarbazepine-induced Stevens-Johnson syndrome in a patient with HLA-B*1502 genotype.

21 January 2018

1 reference

Pilot association study of oxcarbazepine-induced mild cutaneous adverse reactions with HLA-B*1502 allele in Chinese Han population

21 January 2018

1 reference

Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population

21 January 2018

1 reference

HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans

21 January 2018

1 reference

Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan

21 January 2018

1 reference

Strong association between HLA-B*5801 and allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a Thai population

21 January 2018

1 reference

HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol

21 January 2018

1 reference

Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir

21 January 2018

1 reference

SCN1A duplications and deletions detected in Dravet syndrome: implications for molecular diagnosis.

21 January 2018

1 reference

Generalized epilepsy with febrile seizures plus (GEFS+) spectrum: clinical manifestations and SCN1A mutations in Indonesian patients.

21 January 2018

1 reference

Idiopathic epilepsies with seizures precipitated by fever and SCN1A abnormalities.

21 January 2018

1 reference

Genetic contribution to common epilepsies

21 January 2018

1 reference

15q13.3 microdeletions increase risk of idiopathic generalized epilepsy

21 January 2018

1 reference

Recurrent microdeletions at 15q11.2 and 16p13.11 predispose to idiopathic generalized epilepsies

21 January 2018

1 reference

Rare deletions at 16p13.11 predispose to a diverse spectrum of sporadic epilepsy syndromes

21 January 2018

1 reference

Genomic microdeletions associated with epilepsy: not a contraindication to resective surgery

21 January 2018

1 reference

Genetic evaluation and counseling for epilepsy

21 January 2018

1 reference

Hundreds of variants clustered in genomic loci and biological pathways affect human height

21 January 2018

1 reference

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

21 January 2018

1 reference

Defining intractability: comparisons among published definitions

21 January 2018

1 reference

Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study

21 January 2018

1 reference

Association between HLA-B*1502 and carbamazepine-induced severe cutaneous adverse drug reactions in a Thai population

21 January 2018

1 reference

HLA-B*1511 is a risk factor for carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients

21 January 2018

1 reference

HLA class I markers in Japanese patients with carbamazepine-induced cutaneous adverse reactions

21 January 2018

1 reference

Hla-B alleles and lamotrigine-induced cutaneous adverse drug reactions in the Han Chinese population

21 January 2018

1 reference

High-resolution HLA genotyping and severe cutaneous adverse reactions in lamotrigine-treated patients

21 January 2018

1 reference

A functional polymorphism in the SCN1A gene does not influence antiepileptic drug responsiveness in Italian patients with focal epilepsy

21 January 2018

1 reference

Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients

21 January 2018

1 reference

Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment

21 January 2018

1 reference

Population estimation of the effects of cytochrome P450 2C9 and 2C19 polymorphisms on phenobarbital clearance in Japanese.

21 January 2018

1 reference

Pharmacogenetic variation at CYP2C9, CYP2C19, and CYP2D6 at global and microgeographic scales

21 January 2018

1 reference

Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

21 January 2018

1 reference

A common polymorphism in the SCN1A gene associates with phenytoin serum levels at maintenance dose

21 January 2018

1 reference

A pharmacogenetic exploration of vigabatrin-induced visual field constriction

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/PGS.11.85

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25 August 2017

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