(Q37967625)

26 August 2017

title

APC as a mobile scaffold: regulation and function at the nucleus, centrosomes, and mitochondria (English)

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26 August 2017

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Christina Lui

1

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26 August 2017

Kate Mills

2

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26 August 2017

Mariana G Brocardo

3

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26 August 2017

Manisha Sharma

4

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26 August 2017

Beric R Henderson

5

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26 August 2017

publication date

9 December 2011

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26 August 2017

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26 August 2017

volume

64

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26 August 2017

issue

3

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26 August 2017

page(s)

209-214

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APC, signal transduction and genetic instability in colorectal cancer

26 August 2017

cites work

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Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia

21 January 2018

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Wnt signalling and the actin cytoskeleton

21 January 2018

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Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC.

21 January 2018

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The many ways of Wnt in cancer

21 January 2018

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APC shuttling to the membrane, nucleus and beyond

21 January 2018

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The ins and outs of APC and beta-catenin nuclear transport

21 January 2018

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Role of APC and its binding partners in regulating microtubules in mitosis

21 January 2018

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Mitotic spindle misorientation in cancer--out of alignment and into the fire

21 January 2018

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Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover

21 January 2018

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The APC tumour suppressor has a nuclear export function.

21 January 2018

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Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm

21 January 2018

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ARM domain-dependent nuclear import of adenomatous polyposis coli protein is stimulated by the B56 alpha subunit of protein phosphatase 2A.

21 January 2018

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Redefining the subcellular location and transport of APC: new insights using a panel of antibodies.

21 January 2018

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Phosphorylation near nuclear localization signal regulates nuclear import of adenomatous polyposis coli protein

21 January 2018

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Microtubule assembly by the Apc protein is regulated by importin-beta--RanGTP.

21 January 2018

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Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein.

21 January 2018

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The APC protein binds to A/T rich DNA sequences

21 January 2018

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Truncated APC is required for cell proliferation and DNA replication.

21 January 2018

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Adenomatous polyposis coli protein regulates the cellular response to DNA replication stress

21 January 2018

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The APC tumor suppressor inhibits DNA replication by directly binding to DNA via its carboxyl terminus

21 January 2018

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Truncation mutations abolish chromatin-associated activities of adenomatous polyposis coli

21 January 2018

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Protein phosphatase 2A-dependent dephosphorylation of replication protein A is required for the repair of DNA breaks induced by replication stress

21 January 2018

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Tumor suppressor APC blocks DNA polymerase beta-dependent strand displacement synthesis during long patch but not short patch base excision repair and increases sensitivity to methylmethane sulfonate

21 January 2018

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A novel function of adenomatous polyposis coli (APC) in regulating DNA repair

21 January 2018

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APC nuclear membrane association and microtubule polarity

21 January 2018

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Versatility at the nuclear pore complex: lessons learned from the nucleoporin Nup153.

21 January 2018

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Nup358 interacts with APC and plays a role in cell polarization

21 January 2018

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A role for the Adenomatous Polyposis Coli protein in chromosome segregation

21 January 2018

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Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

21 January 2018

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Novel association of APC with intermediate filaments identified using a new versatile APC antibody

21 January 2018

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LINCing lamin B2 to neuronal migration: growing evidence for cell-specific roles of B-type lamins.

21 January 2018

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Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes.

21 January 2018

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Aneuploid colon cancer cells have a robust spindle checkpoint

21 January 2018

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Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry

21 January 2018

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A Nup133-dependent NPC-anchored network tethers centrosomes to the nuclear envelope in prophase.

21 January 2018

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Oncogenes and tumour suppressors take on centrosomes

21 January 2018

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Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis

21 January 2018

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Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability.

21 January 2018

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Caspase cleavage of the APC tumor suppressor and release of an amino-terminal domain is required for the transcription-independent function of APC in apoptosis

21 January 2018

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Truncated APC regulates the transcriptional activity of beta-catenin in a cell cycle dependent manner

21 January 2018

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Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: regulation of Bcl-2 and implications for cell survival

21 January 2018

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The mitochondrial protein hTID-1 partners with the caspase-cleaved adenomatous polyposis cell tumor suppressor to facilitate apoptosis

21 January 2018

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The APC Tumor Suppressor Promotes Transcription-Independent Apoptosis In vitro

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IUB.599

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26 August 2017

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