(Q37976887)

26 August 2017

title

The GM-CSF receptor family: mechanism of activation and implications for disease (English)

1 reference

26 August 2017

Joanna M Woodcock

7

0 references

Hayley S. Ramshaw

Hayley S Ramshaw

4

0 references

Paul G Ekert

Paul G Ekert

3

0 references

Stuart M Pitson

Stuart Pitson

9

0 references

Angel F. Lopez

Angel F Lopez

13

0 references

Michael W Parker

Michael W Parker

12

0 references

Timothy R Hercus

Timothy R Hercus

1

0 references

author name string

Sophie E Broughton

2

1 reference

26 August 2017

Michelle Perugini

5

1 reference

26 August 2017

Michele Grimbaldeston

6

1 reference

26 August 2017

Daniel Thomas

8

1 reference

26 August 2017

Timothy Hughes

10

1 reference

26 August 2017

Richard J D'Andrea

11

1 reference

26 August 2017

publication date

18 January 2012

1 reference

26 August 2017

published in

Growth Factors Journal

1 reference

26 August 2017

volume

30

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26 August 2017

issue

2

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26 August 2017

page(s)

63-75

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14-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survival.

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

A new isoform of interleukin-3 receptor {alpha} with novel differentiation activity and high affinity binding mode

21 January 2018

1 reference

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21 January 2018

The BCL-2 family reunion

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Overlapping motifs in the membrane-proximal region of cytokine receptor accessory and signaling subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

A cytokine-cytokine interaction in the assembly of higher-order structure and activation of the interleukine-3:receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Granulocyte-macrophage colony-stimulating factor signals for increased glucose transport via phosphatidylinositol 3-kinase- and hydrogen peroxide-dependent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

IL-3 induces a Pim1-dependent antiapoptotic pathway in primary human basophils

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Unresponsiveness of primitive chronic myeloid leukemia cells to macrophage inflammatory protein 1 alpha, an inhibitor of primitive normal hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Cell death provoked by loss of interleukin-3 signaling is independent of Bad, Bim, and PI3 kinase, but depends in part on Puma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Functions of granulocyte-macrophage colony-stimulating factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Phosphorylation of Puma modulates its apoptotic function by regulating protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Long-term follow-up and treatment of congenital alveolar proteinosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

The phosphoserine-585-dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-kappaB and induction of bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor promote malignant growth of cells from head and neck squamous cell carcinomas in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Colony-stimulating factors in inflammation and autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Specific human granulocyte-macrophage colony-stimulating factor antagonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Fc receptor gamma-chain, a constitutive component of the IL-3 receptor, is required for IL-3-induced IL-4 production in basophils

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Blocking cytokine signaling along with intense Bcr-Abl kinase inhibition induces apoptosis in primary CML progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Multisite phosphorylation regulates Bim stability and apoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Characteristics of a large cohort of patients with autoimmune pulmonary alveolar proteinosis in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Single cell profiling of potentiated phospho-protein networks in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Definition of the role of tyrosine residues of the common beta subunit regulating multiple signaling pathways of granulocyte-macrophage colony-stimulating factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Myeloid progenitor cells lacking p53 exhibit delayed up-regulation of Puma and prolonged survival after cytokine deprivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Targeting of CD44 eradicates human acute myeloid leukemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

CBAP interacts with the un-liganded common beta-subunit of the GM-CSF/IL-3/IL-5 receptor and induces apoptosis via mitochondrial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Recombinant interleukin 4 stimulates human immunodeficiency virus production by infected monocytes and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

The many paths to asthma: phenotype shaped by innate and adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Deoxyribonucleic acid triplex formation inhibits granulocyte macrophage colony-stimulating factor gene expression and suppresses growth in juvenile myelomonocytic leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Recombinant human interleukin 5 is a selective activator of human eosinophil function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Molecular basis of cytokine receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Molecular Basis for Shared Cytokine Recognition Revealed in the Structure of an Unusually High Affinity Complex between IL-13 and IL-13Rα2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Structural snapshots of full-length Jak1, a transmembrane gp130/IL-6/IL-6Rα cytokine receptor complex, and the receptor-Jak1 holocomplex

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Monoclonal antibody therapy directed against human acute myeloid leukemia stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Cancer-related inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Molecular assembly of the ternary granulocyte-macrophage colony-stimulating factor receptor complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Dendritic cells: specialized and regulated antigen processing machines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

21 January 2018

Hematopoietic cytokines

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

The colony-stimulating factors and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

The Ig-like domain of human GM-CSF receptor alpha plays a critical role in cytokine binding and receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Identification of osteopontin-dependent signaling pathways in a mouse model of human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte macrophage colony-stimulating factor in human gliomas with tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Jak2 is essential for signaling through a variety of cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

NF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common beta-subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Evidence for a physical association between the Shc-PTB domain and the beta c chain of the granulocyte-macrophage colony-stimulating factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Interleukin (IL)-3/granulocyte macrophage-colony stimulating factor/IL-5 receptor alpha and beta chains are preferentially expressed in acute myeloid leukaemias with mutated FMS-related tyrosine kinase 3 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

The regulation of TNF signalling: what a tangled web we weave

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Cytoplasmic domains of the common beta-chain of the GM-CSF/IL-3/IL-5 receptors that are required for inducing differentiation or clonal suppression in myeloid leukaemic cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Selective roles for antiapoptotic MCL-1 during granulocyte development and macrophage effector function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Hereditary pulmonary alveolar proteinosis: pathogenesis, presentation, diagnosis, and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Adult-onset hereditary pulmonary alveolar proteinosis caused by a single-base deletion in CSF2RB.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Identification of receptor-binding domains on human interleukin 5 and design of an interleukin 5-derived receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Which AML subsets benefit from leukemic cell priming during chemotherapy? Long-term analysis of the ALFA-9802 GM-CSF study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Inhibition of β1 integrin and IL-3Rβ common subunit interaction hinders tumour angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

The novel AML stem cell associated antigen CLL-1 aids in discrimination between normal and leukemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Structural biology of shared cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Human GM-CSF: molecular cloning of the complementary DNA and purification of the natural and recombinant proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

A single tyrosine residue in the membrane-proximal domain of the granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptor common beta-chain is necessary and sufficient for high affinity binding and signaling by all thr

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08977194.2011.649919

10.3109/08977194.2011.649919

21 January 2018

Identifiers

DOI

1 reference

release_n372rz5c4jczxkwslu7kowg47q

26 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/n372rz5c4jczxkwslu7kowg47q

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference