(Q37979243)

26 August 2017

title

Molecular scissors for in situ cellular repair (English)

1 reference

26 August 2017

Jesús Prieto

1

1 reference

26 August 2017

Rafael Molina

series ordinal

2

1 reference

26 August 2017

Guillermo Montoya

series ordinal

3

1 reference

26 August 2017

publication date

28 January 2012

1 reference

Critical Reviews in Biochemistry and Molecular Biology

26 August 2017

published in

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26 August 2017

volume

47

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26 August 2017

issue

3

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26 August 2017

page(s)

207-221

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Custom zinc-finger nucleases for use in human cells.

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Genetic correction of DNA repair-deficient/cancer-prone xeroderma pigmentosum group C keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

The I-CreI meganuclease and its engineered derivatives: applications from cell modification to gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Engineered I-CreI derivatives cleaving sequences from the human XPC gene can induce highly efficient gene correction in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Computational redesign of endonuclease DNA binding and cleavage specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Native homing endonucleases can target conserved genes in humans and in animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Positive and negative regulation of endogenous genes by designed transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

FokI dimerization is required for DNA cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Breaking the code of DNA binding specificity of TAL-type III effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Meganuclease-driven targeted integration in CHO-K1 cells for the fast generation of HTS-compatible cell-based assays

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Progress and prospects: zinc-finger nucleases as gene therapy agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Genome Engineering With Zinc-Finger Nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Zinc-finger nucleases: a panoramic view

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Tracking genome engineering outcome at individual DNA breakpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Meganucleases can restore the reading frame of a mutated dystrophin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Directed evolution of homing endonuclease I-SceI with altered sequence specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Metal-dependent DNA cleavage mechanism of the I-CreI LAGLIDADG homing endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Design, activity, and structure of a highly specific artificial endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Homing endonucleases: structural and functional insight into the catalysts of intron/intein mobility

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Targeting DNA double-strand breaks with TAL effector nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

A summary of mutations in the UV-sensitive disorders: Xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

I-SceI-induced gene replacement at a natural locus in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Hematopoietic stem-cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Peripheral blood stem cells for allogeneic transplantation: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Importance of the cell cycle phase for the choice of the appropriate DSB repair pathway, for genome stability maintenance: the trans-S double-strand break repair model

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Directed evolution and substrate specificity profile of homing endonuclease I-SceI.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Gene conversion tracts from double-strand break repair in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

An unbiased genome-wide analysis of zinc-finger nuclease specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Heritable targeted mutagenesis in maize using a designed endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Efficient in toto targeted recombination in mouse liver by meganuclease-induced double-strand break

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Context dependence between subdomains in the DNA binding interface of the I-CreI homing endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Generation of redesigned homing endonucleases comprising DNA-binding domains derived from two different scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Meganuclease-mediated Inhibition of HSV1 Infection in Cultured Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Expanding or restricting the target site repertoire of zinc-finger nucleases: the inter-domain linker as a major determinant of target site selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Genetic engineering of human pluripotent cells using TALE nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

p53 protein transduction therapy: successful targeting and inhibition of the growth of the bladder cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

DNA recognition and cleavage by the LAGLIDADG homing endonuclease I-CreI

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Progress and prospects: human artificial chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Methods for homologous recombination in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Homing endonucleases: from basics to therapeutic applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Crystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Modeling the therapeutic efficacy of p53 restoration in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Single-strand nicks induce homologous recombination with less toxicity than double-strand breaks using an AAV vector template

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

The NH2 terminus of influenza virus hemagglutinin-2 subunit peptides enhances the antitumor potency of polyarginine-mediated p53 protein transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Human Gene Targeting by Adeno-Associated Virus Vectors Is Enhanced by DNA Double-Strand Breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

A TALE nuclease architecture for efficient genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Nucleases and helicases take center stage in homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Loss of heterozygosity induced by a chromosomal double-strand break

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Engineering variants of the I-SceI homing endonuclease with strand-specific and site-specific DNA-nicking activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Designer zinc-finger proteins and their applications

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Meganucleases and DNA double-strand break-induced recombination: perspectives for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Frequent endonuclease cleavage at off-target locations in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Mammalian gene targeting with designed zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Chimeric nucleases stimulate gene targeting in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Two different but related mechanisms are used in plants for the repair of genomic double-strand breaks by homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Zinc-finger nucleases: a powerful tool for genetic engineering of animals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Targeted mutagenesis by homologous recombination in D. melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Homing endonuclease I-CreI derivatives with novel DNA target specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Mutations altering the cleavage specificity of a homing endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Accurate homologous recombination is a prominent double-strand break repair pathway in mammalian chromosomes and is modulated by mismatch repair protein Msh2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Isolation and characterization of new homing endonuclease specificities at individual target site positions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Tapping natural reservoirs of homing endonucleases for targeted gene modification

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Stem cell-mediated transfer of a human artificial chromosome ameliorates muscular dystrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

I-SceI meganuclease mediates highly efficient transgenesis in fish.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Genome editing with engineered zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Restoration of p53 function leads to tumour regression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Protein transduction technology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Homing endonuclease mediated gene targeting in Anopheles gambiae cells and embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Dr.VIS: a database of human disease-related viral integration sites

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

Generation of induced pluripotent stem cells using recombinant proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2011.652358

10.3109/10409238.2011.652358

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference