(Q37979995)

26 August 2017

title

Protein kinase CK2 in hematologic malignancies: reliance on a pivotal cell survival regulator by oncogenic signaling pathways (English)

1 reference

26 August 2017

M Ruzzene

3

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Francesco Piazza

object named as

F Piazza

1

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Gianpietro Semenzato

object named as

G Semenzato

6

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author name string

S Manni

2

1 reference

26 August 2017

L A Pinna

4

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26 August 2017

C Gurrieri

5

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26 August 2017

publication date

13 January 2012

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26 August 2017

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26 August 2017

volume

26

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26 August 2017

issue

6

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26 August 2017

page(s)

1174-1179

1 reference

https://scigraph.springernature.com/pub.10.1038/leu.2011.385

26 August 2017

exact match

0 references

cites work

Protein kinase CK2 in health and disease: From birth to death: the role of protein kinase CK2 in the regulation of cell proliferation and survival

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

21 January 2018

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One-thousand-and-one substrates of protein kinase CK2?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Disruption of the regulatory beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Gene targeting of CK2 catalytic subunits

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Globozoospermia in mice lacking the casein kinase II alpha' catalytic subunit

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Protein kinase CK2 in health and disease: CK2: a key player in cancer biology

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The emerging CK2 interactome: insights into the regulation and functions of CK2.

21 January 2018

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Protein kinase CK2 in health and disease: Cellular functions of protein kinase CK2: a dynamic affair.

21 January 2018

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When pathways collide: collaboration and connivance among signalling proteins in development.

21 January 2018

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CK2 as a positive regulator of Wnt signalling and tumourigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

CK2 controls the recruitment of Wnt regulators to target genes in vivo

21 January 2018

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Phosphorylation of AKT/PKB by CK2 is necessary for the AKT-dependent up-regulation of β-catenin transcriptional activity.

21 January 2018

1 reference

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CK2 functionally interacts with AKT/PKB to promote the β-catenin-dependent expression of survivin and enhance cell survival.

21 January 2018

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Hedgehog signaling in development and cancer.

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The controversial role of the Hedgehog pathway in normal and malignant hematopoiesis.

21 January 2018

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Casein kinase 2 promotes Hedgehog signaling by regulating both smoothened and Cubitus interruptus

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.385

The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1

21 January 2018

1 reference

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Tenets of PTEN tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

21 January 2018

1 reference

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The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation

21 January 2018

1 reference

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Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta

21 January 2018

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The impact of PTEN regulation by CK2 on PI3K-dependent signaling and leukemia cell survival

21 January 2018

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Protein kinase CK2 phosphorylates and upregulates Akt/PKB.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.385

Dephosphorylation and inactivation of Akt/PKB is counteracted by protein kinase CK2 in HEK 293T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Constitutive c-Myb amino-terminal phosphorylation and DNA binding activity uncoupled during entry and passage through the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Sp1 phosphorylation and its regulation of gene transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

CK2 mediates phosphorylation and ubiquitin-mediated degradation of the PML tumor suppressor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

The Genetic Basis of Autoimmune Disease in MRL-lpr/lpr Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

p53 deficiency and misexpression of protein kinase CK2alpha collaborate in the development of thymic lymphomas in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Protein kinase CKIIα interacts with the Bcr moiety of Bcr/Abl and mediates proliferation of Bcr/Abl-expressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

21 January 2018

1 reference

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Regulation of PTEN by CK2 and Notch1 in primary T-cell acute lymphoblastic leukemia: rationale for combined use of CK2- and gamma-secretase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Targeting CK2 overexpression and hyperactivation as a novel therapeutic tool in chronic lymphocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Multiple myeloma cell survival relies on high activity of protein kinase CK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Protein kinases in human leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Multiple forms of protein kinase CK2 present in leukemic cells: in vitro study of its origin by proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Protein kinase CK2alpha is a target for the Abl and Bcr-Abl tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.385

A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Involvement of protein kinase CK2 in angiogenesis and retinal neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Addiction to protein kinase CK2: a common denominator of diverse cancer cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Non-oncogene addiction and the stress phenotype of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Pharmacological inhibition of protein kinase CK2 reverts the multidrug resistance phenotype of a CEM cell line characterized by high CK2 level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Protein kinase CK2 accumulation in "oncophilic" cells: causes and effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Treatment of P190 Bcr/Abl lymphoblastic leukemia cells with inhibitors of the serine/threonine kinase CK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.385

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/LEU.2011.385

1 reference

Dimensions Publication ID

26 August 2017

1012402617

0 references

1 reference