(Q37981834)

26 August 2017

New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and autophagy (English)

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26 August 2017

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26 August 2017

J S Long

1

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PubMed ID

22310284

26 August 2017

language of work or name

English

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publication date

6 February 2012

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26 August 2017

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26 August 2017

31

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26 August 2017

49

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26 August 2017

5045-5060

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https://scigraph.springernature.com/pub.10.1038/onc.2012.7

26 August 2017

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cites work

The roles of therapy-induced autophagy and necrosis in cancer treatment

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Lysosomal biogenesis and function is critical for necrotic cell death in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Death receptors: signaling and modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

A tangled web of ubiquitin chains: breaking news in TNF-R1 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Lysosomal membrane permeabilization in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Institutional experience with chloroquine as an adjuvant to the therapy for glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

PRIMA-1(MET) synergizes with cisplatin to induce tumor cell apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Harnessing synthetic lethal interactions in anticancer drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Interdigital cell death can occur through a necrotic and caspase-independent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Smac mimetics as new cancer therapeutics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Mechanisms of necroptosis in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Novel targeted deregulation of c-Myc cooperates with Bcl-X(L) to cause plasma cell neoplasms in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Treatment of B-RAF mutant human tumor cells with a MEK inhibitor requires Bim and is enhanced by a BH3 mimetic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

AIF-mediated caspase-independent necroptosis: a new chance for targeted therapeutics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Participation of lysosomes in cellular autophagy induced in rat liver by glucagon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Apoptosis: a review of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

The role of phosphatidylserine in recognition of apoptotic cells by phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Cooperative interaction between c-myc and bcl-2 proto-oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Loss of proapoptotic Bcl-2-related multidomain proteins in primary melanomas is associated with poor prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Basal caspase activity promotes migration and invasiveness in glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Apoptosis and cancer: mutations within caspase genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

The role of apoptosis in wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Apoptosis and necrosis: mechanisms of cell death induced by cyclosporine A in a renal proximal tubular cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Kill one bird with two stones: potential efficacy of BCR-ABL and autophagy inhibition in CML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

The biochemistry of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

The inhibitors of apoptosis (IAPs) as cancer targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Autophagy gene disruption reveals a non-vacuolar cell death pathway in Dictyostelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

21 January 2018

Death receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Sequential bcl-2 and c-myc oncogene rearrangements associated with the clinical transformation of non-Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Weak p53 permits senescence during cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Autophagy in cell death: an innocent convict?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Pharmacology of adapalene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Intrinsic tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Autophagy suppresses tumorigenesis through elimination of p62

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Autophagy suppresses tumor progression by limiting chromosomal instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Apoptosis evasion: the role of survival pathways in prostate cancer progression and therapeutic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

p53 has a direct apoptogenic role at the mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Active participation of cell death in development and organismal homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Autophagosome formation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Autophagy fights disease through cellular self-digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Caspase 8 inhibits programmed necrosis by processing CYLD

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Differential activity of caspase-3 regulates susceptibility of lung and breast tumor cell lines to Paclitaxel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Towards novel paradigms for cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

The role of autophagy in tumour development and cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

The multiple roles of autophagy in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Toxic proteins released from mitochondria in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Apoptosome: the seven-spoked death machine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Autophagy is required for necrotic cell death in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

BID regulation by p53 contributes to chemosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Reduced autophagic activity, improved protein balance and enhanced in vitro survival of hepatocytes isolated from carcinogen-treated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Association and dissociation of autophagy, apoptosis and necrosis by systematic chemical study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Alternative cell death of Apaf1-deficient neural progenitor cells induced by withdrawal of EGF or insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Increased apoptosis in metastatic human colonic adenocarcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

The role of apoptosis in the pathogenesis and treatment of diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Randomized phase II study of dulanermin in combination with paclitaxel, carboplatin, and bevacizumab in advanced non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Mitochondria and cell death: outer membrane permeabilization and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Autophagy-deficient mice develop multiple liver tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Regulation of autophagy by cytoplasmic p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Molecular mechanisms of necroptosis: an ordered cellular explosion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Pharmacological reactivation of mutant p53: from protein structure to the cancer patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Negative regulation of bcl-2 expression by p53 in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Autophagy plays a protective role during zVAD-induced necrotic cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFα mediated by the PKC-MAPKs-AP-1 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Pancreatic cancers require autophagy for tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

RIP3 beta and RIP3 gamma, two novel splice variants of receptor-interacting protein 3 (RIP3), downregulate RIP3-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Eaten alive: a history of macroautophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Knockdown of second mitochondria-derived activator of caspase expression by RNAi enhances growth and cisplatin resistance of human lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Functional complementation between FADD and RIP1 in embryos and lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Alkylating DNA damage stimulates a regulated form of necrotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Induction of autophagy by amino-acid deprivation in perfused rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis to autophagy in HeLa cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Ambra1 regulates autophagy and development of the nervous system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

A matter of life and death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Differential inactivation of caspase-8 in lung cancers.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Involvement of the bcl-2 gene in human follicular lymphoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.7

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/ONC.2012.7

1 reference

26 August 2017

1 reference

PubMed ID

22310284