(Q37988922)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22372633%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

HDAC6 at the Intersection of Neuroprotection and Neurodegeneration (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22372633%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22372633%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

author name string

Constantin d'Ydewalle

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22372633%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Elke Bogaert

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22372633%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

language of work or name

1 reference

26 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22372633%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22372633%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22372633%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22372633%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

page(s)

771-779

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22372633%20AND%20SRC:MED&resulttype=core&format=json

Epigenetics in human disease and prospects for epigenetic therapy

24 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Anticancer activities of histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Histone acetylation in chromatin structure and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Histone acetylation: chromatin in action

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

HDAC6 is a microtubule-associated deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Impaired function of HDAC6 slows down axonal growth and interferes with axon initial segment development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

HDAC6 regulates mitochondrial transport in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

TPPP/p25 promotes tubulin acetylation by inhibiting histone deacetylase 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Histone deacetylase 6 interacts with the microtubule-associated protein tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Tau--an inhibitor of deacetylase HDAC6 function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Acetylation of tau inhibits its degradation and contributes to tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Role of axonal transport in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

HDAC6 modulates cell motility by altering the acetylation level of cortactin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

An acetylation site in the middle domain of Hsp90 regulates chaperone function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Class II histone deacetylases play pivotal roles in heat shock protein 90-mediated proteasomal degradation of vascular endothelial growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

VEGF protects motor neurons against excitotoxicity by upregulation of GluR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Autophagy in neurodegeneration: two sides of the same coin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

The deacetylase HDAC6 is a novel critical component of stress granules involved in the stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Inhibition of the ubiquitin-proteasome system induces stress granule formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

A BBSome subunit links ciliogenesis, microtubule stability, and acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

The NIMA-family kinase Nek3 regulates microtubule acetylation in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Drosophila histone deacetylase 6 protects dopaminergic neurons against {alpha}-synuclein toxicity by promoting inclusion formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Hdac6 knock-out increases tubulin acetylation but does not modify disease progression in the R6/2 mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Exome sequencing reveals VCP mutations as a cause of familial ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Pathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a Drosophila IBMPFD model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Deficits in axonal transport precede ALS symptoms in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

A mutation in the small heat-shock protein HSPB1 leading to distal hereditary motor neuronopathy disrupts neurofilament assembly and the axonal transport of specific cellular cargoes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Disruption of neurofilament network with aggregation of light neurofilament protein: a common pathway leading to motor neuron degeneration due to Charcot-Marie-Tooth disease-linked mutations in NFL and HSPB1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

The formation of peripheral myelin protein 22 aggregates is hindered by the enhancement of autophagy and expression of cytoplasmic chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Multiple disease-linked myotubularin mutations cause NFL assembly defects in cultured cells and disrupt myotubularin dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

HDAC6 is a target for protection and regeneration following injury in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X

Effects of vascular endothelial growth factor (VEGF) on motor neuron degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2012.01347.X