(Q37995466)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433952%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Posttranslational control of telomere maintenance and the telomere damage response (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433952%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author

Jacqueline J.L. Jacobs

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433952%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Marieke H Peuscher

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433952%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

publication date

15 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433952%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

number of pages

11

1 reference

based on heuristic

inferred from page(s)

published in

Cell Cycle

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433952%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433952%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433952%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

1524-1534

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22433952%20AND%20SRC:MED&resulttype=core&format=json

Hallmarks of Cancer: The Next Generation

26 January 2020

cites work

1 reference

Genome instability: a mechanistic view of its causes and consequences

21 January 2018

1 reference

How telomeres solve the end-protection problem

21 January 2018

1 reference

How shelterin solves the telomere end-protection problem

21 January 2018

1 reference

Telomeres shorten during ageing of human fibroblasts

21 January 2018

1 reference

The causes and consequences of polyploidy in normal development and cancer

21 January 2018

1 reference

Role of shelterin in cancer and aging

21 January 2018

1 reference

A DNA damage checkpoint response in telomere-initiated senescence

21 January 2018

1 reference

DNA damage foci at dysfunctional telomeres

21 January 2018

1 reference

Telomeres and telomerase in cancer

21 January 2018

1 reference

Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins

21 January 2018

1 reference

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

21 January 2018

1 reference

DNA-damage response and repair activities at uncapped telomeres depend on RNF8

21 January 2018

1 reference

Structural identity of telomeric complexes

21 January 2018

1 reference

The epigenetic regulation of mammalian telomeres

21 January 2018

1 reference

A role for heterochromatin protein 1γ at human telomeres

21 January 2018

1 reference

The human telomeric protein hTRF1 induces telomere-specific nucleosome mobility

21 January 2018

1 reference

Conserved nucleoprotein structure at the ends of vertebrate and invertebrate chromosomes

21 January 2018

1 reference

No overt nucleosome eviction at deprotected telomeres

21 January 2018

1 reference

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

21 January 2018

1 reference

Telomeres and telomerase in adult stem cells and pluripotent embryonic stem cells.

21 January 2018

1 reference

Extension of life-span by introduction of telomerase into normal human cells

21 January 2018

1 reference

Telomerase and cancer therapeutics

21 January 2018

1 reference

Alternative lengthening of telomeres: models, mechanisms and implications

21 January 2018

1 reference

RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis

21 January 2018

1 reference

The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks

21 January 2018

1 reference

Cellular stress response pathways and ageing: intricate molecular relationships

21 January 2018

1 reference

Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae

21 January 2018

1 reference

CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination.

21 January 2018

1 reference

The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair

21 January 2018

1 reference

Human telomerase activity regulation.

21 January 2018

1 reference

Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT.

21 January 2018

1 reference

Hdm2 negatively regulates telomerase activity by functioning as an E3 ligase of hTERT.

21 January 2018

1 reference

CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity

21 January 2018

1 reference

The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor

21 January 2018

1 reference

Carboxyl terminus of Hsp70-interacting protein (CHIP) contributes to human glioma oncogenesis

21 January 2018

1 reference

Control of telomere length by the human telomeric protein TRF1

21 January 2018

1 reference

TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres

21 January 2018

1 reference

The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance

21 January 2018

1 reference

Structural basis of selective ubiquitination of TRF1 by SCFFbx4

21 January 2018

1 reference

Ubiquitin Ligase RLIM Modulates Telomere Length Homeostasis through a Proteolysis of TRF1.

21 January 2018

1 reference

Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance.

21 January 2018

1 reference

Deubiquitination of histone H2B by a yeast acetyltransferase complex regulates transcription.

21 January 2018

1 reference

TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex

21 January 2018

1 reference

Protein requirements for sister telomere association in human cells

21 January 2018

1 reference

TIN2 stability is regulated by the E3 ligase Siah2.

21 January 2018

1 reference

A role for monoubiquitinated FANCD2 at telomeres in ALT cells

21 January 2018

1 reference

CST meets shelterin to keep telomeres in check

21 January 2018

1 reference

Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression.

21 January 2018

1 reference

SUMOylation regulates telomere length homeostasis by targeting Cdc13.

21 January 2018

1 reference

The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast.

21 January 2018

1 reference

Role of SUMO in the dynamics of telomere maintenance in fission yeast

21 January 2018

1 reference

Sumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution

21 January 2018

1 reference

The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins

21 January 2018

1 reference

Sumoylation of RecQ helicase controls the fate of dysfunctional telomeres.

21 January 2018

1 reference

Sumoylation of the BLM ortholog, Sgs1, promotes telomere-telomere recombination in budding yeast.

21 January 2018

1 reference

RecQ helicases in DNA double strand break repair and telomere maintenance

21 January 2018

1 reference

RECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenance

21 January 2018

1 reference

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

21 January 2018

1 reference

Multiple roles for MRE11 at uncapped telomeres

21 January 2018

1 reference

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

21 January 2018

1 reference

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

21 January 2018

1 reference

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

21 January 2018

1 reference

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

21 January 2018

1 reference

Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

21 January 2018

1 reference

Fusing telomeres with RNF8.

21 January 2018

1 reference

The E3 ubiquitin ligase Rnf8 stabilizes Tpp1 to promote telomere end protection

21 January 2018

1 reference

Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.

21 January 2018

1 reference

Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence.

21 January 2018

1 reference

Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases.

21 January 2018

1 reference

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

21 January 2018

1 reference

Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres

21 January 2018

1 reference

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres

21 January 2018

1 reference

Suv4-20h abrogation enhances telomere elongation during reprogramming and confers a higher tumorigenic potential to iPS cells

21 January 2018

1 reference

SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

21 January 2018

1 reference

Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction

21 January 2018

1 reference

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

21 January 2018

1 reference

Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6.

21 January 2018

1 reference

SIRT1 contributes to telomere maintenance and augments global homologous recombination

21 January 2018

1 reference

SIRT6 is required for maintenance of telomere position effect in human cells

21 January 2018

1 reference

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

21 January 2018

1 reference

Resolution of sister telomere association is required for progression through mitosis

21 January 2018

1 reference

Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs

21 January 2018

1 reference

Tankyrase-1 function at telomeres and during mitosis is regulated by Polo-like kinase-1-mediated phosphorylation

21 January 2018

1 reference

Plk1 phosphorylation of TRF1 is essential for its binding to telomeres

21 January 2018

1 reference

Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner

21 January 2018

1 reference

DNA damage-induced phosphorylation of the human telomere-associated protein TRF2.

21 January 2018

1 reference

The shelterin protein TRF2 inhibits Chk2 activity at telomeres in the absence of DNA damage.

21 January 2018

1 reference

Cell-cycle-dependent Xenopus TRF1 recruitment to telomere chromatin regulated by Polo-like kinase

21 January 2018

1 reference

MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control

21 January 2018

1 reference

Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation

21 January 2018

1 reference

ATM regulates proteasome-dependent subnuclear localization of TRF1, which is important for telomere maintenance.

21 January 2018

1 reference

Cyclin B-dependent kinase 1 regulates human TRF1 to modulate the resolution of sister telomeres.

21 January 2018

1 reference

Phosphorylation of telomeric repeat binding factor 1 (TRF1) by Akt causes telomere shortening

21 January 2018

1 reference

Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer

21 January 2018

1 reference

Ubiquitylation and the Fanconi anemia pathway

21 January 2018

1 reference

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

21 January 2018

1 reference

Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome

21 January 2018

1 reference

Significant Role for p16INK4a in p53-Independent Telomere-Directed Senescence

21 January 2018

1 reference

DNA methyltransferases control telomere length and telomere recombination in mammalian cells

21 January 2018

1 reference

Tankyrase promotes telomere elongation in human cells

21 January 2018

1 reference