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RecQ helicases in DNA double strand break repair and telomere maintenance
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PubMed
review article
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Europe PubMed Central
title
RecQ helicases in DNA double strand break repair and telomere maintenance
(English)
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PubMed
author name string
Singh DK
series ordinal
1
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PubMed
Ghosh AK
series ordinal
2
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stated in
PubMed
Croteau DL
series ordinal
3
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stated in
PubMed
Bohr VA
series ordinal
4
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PubMed
language of work or name
English
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publication date
1 August 2012
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stated in
PubMed
published in
Mutation Research
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stated in
PubMed
volume
736
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stated in
PubMed
issue
1-2
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stated in
PubMed
page(s)
15-24
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PubMed
cites work
The RecQ DNA helicases in DNA repair
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Roles of Werner syndrome protein in protection of genome integrity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Purification of proteins associated with specific genomic Loci
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Identification of RecQL1 as a Holliday junction processing enzyme in human cell lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Functional interaction between the Bloom's syndrome helicase and the RAD51 paralog, RAD51L3 (RAD51D)
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
WRN interacts physically and functionally with the recombination mediator protein RAD52
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Ku heterodimer binds to both ends of the Werner protein and functional interaction occurs at the Werner N-terminus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
The Bloom's syndrome gene product promotes branch migration of holliday junctions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Ku complex interacts with and stimulates the Werner protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Mammalian telomeres end in a large duplex loop
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Chromosomal double-strand break repair in Ku80-deficient cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Recombination-mediated lengthening of terminal telomeric repeats requires the Sgs1 DNA helicase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Telomeric D-loops containing 8-oxo-2'-deoxyguanosine are preferred substrates for Werner and Bloom syndrome helicases and are bound by POT1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Molecular views of recombination proteins and their control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
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20 March 2017
Recombinational DNA repair and human disease
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Evidence for BLM and Topoisomerase IIIalpha interaction in genomic stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Two primary osteosarcomas in a patient with Rothmund-Thomson syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
The Bloom's syndrome gene product interacts with topoisomerase III
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Regulation of DNA double-strand break repair pathway choice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
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20 March 2017
Shelterin: the protein complex that shapes and safeguards human telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
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20 March 2017
Pathways and functions of the Werner syndrome protein
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
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20 March 2017
Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
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20 March 2017
Senescence Induced by Altered Telomere State, Not Telomere Loss
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
Essential role of limiting telomeres in the pathogenesis of Werner syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
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20 March 2017
Origin of Concatemeric T7DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
20 March 2017
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
7 April 2017
Telomeres shorten during ageing of human fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
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7 April 2017
A DNA damage checkpoint response in telomere-initiated senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
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7 April 2017
Protection of mammalian telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
7 April 2017
Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
7 April 2017
Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
The Werner syndrome protein suppresses telomeric instability caused by chromium (VI) induced DNA replication stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Human telomeres are hypersensitive to UV-induced DNA Damage and refractory to repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Physical interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
The involvement of human RECQL4 in DNA double-strand break repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
The Caenorhabditis elegans Werner syndrome protein functions upstream of ATR and ATM in response to DNA replication inhibition and double-strand DNA breaks.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
RecQ helicases: multifunctional genome caretakers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Choreography of recombination proteins during the DNA damage response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
MRE11 complex links RECQ5 helicase to sites of DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Effects of hTERT on genomic instability caused by either metal or radiation or combined exposure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Drosophila homologue of the Rothmund-Thomson syndrome gene: essential function in DNA replication during development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
RecQ4 facilitates UV light-induced DNA damage repair through interaction with nucleotide excision repair factor xeroderma pigmentosum group A (XPA)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Mechanism and substrate specificity of telomeric protein POT1 stimulation of the Werner syndrome helicase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
A RECQ5-RNA polymerase II association identified by targeted proteomic analysis of human chromatin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
RECQ1 possesses DNA branch migration activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Association of human DNA helicase RecQ5beta with RNA polymerase II and its possible role in transcription.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Human RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Telomere ResQue and preservation--roles for the Werner syndrome protein and other RecQ helicases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Novel pro- and anti-recombination activities of the Bloom's syndrome helicase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Holliday junction processing activity of the BLM-Topo IIIalpha-BLAP75 complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Correction of proliferation and drug sensitivity defects in the progeroid Werner's Syndrome by Holliday junction resolution.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Telomere dysfunction as a cause of genomic instability in Werner syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
BLM is an early responder to DNA double-strand breaks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
DNA helicases required for homologous recombination and repair of damaged replication forks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Collaboration of Werner syndrome protein and BRCA1 in cellular responses to DNA interstrand cross-links
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
A double Holliday junction dissolvasome comprising BLM, topoisomerase IIIalpha, and BLAP75.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Accumulation of Werner protein at DNA double-strand breaks in human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Mechanism of DNA double-strand break repair by non-homologous end joining
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Ultraviolet radiation-mediated damage to cellular DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Expression of a RecQ helicase homolog affects progression through crisis in fission yeast lacking telomerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Functional links between telomeres and proteins of the DNA-damage response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Linkage between Werner syndrome protein and the Mre11 complex via Nbs1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Mechanism and regulation of human non-homologous DNA end-joining
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
The Bloom's syndrome helicase interacts directly with the human DNA mismatch repair protein hMSH6.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Rad51 recombinase and recombination mediators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Homologous recombination resolution defect in werner syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Displacement of DNA-PKcs from DNA ends by the Werner syndrome protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Unwinding the molecular basis of the Werner syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Molecular mechanisms of DNA double strand break repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Preferential accumulation of single-stranded regions in telomeres of human fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Chromium(VI) treatment of normal human lung cells results in guanine-specific DNA polymerase arrest, DNA-DNA cross-links and S-phase blockade of cell cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
DNA damage and repair in telomeres: relation to aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Bloom's syndrome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
The molecular structure of centromeres and telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Principle of marginotomy in template synthesis of polynucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Rothmund-Thomson syndrome: review of the world literature
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
29 September 2017
Sequence-specific DNA cleavage by Fe2+-mediated fenton reactions has possible biological implications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
2 June 2018
Arrest of replication by mammalian DNA polymerases alpha and beta caused by chromium-DNA lesions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
2 June 2018
Telomeres, telomerase and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
2 June 2018
Clonal lines of aneuploid cells in Rothmund-Thomson syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
2 June 2018
An abnormal profile of DNA replication intermediates in Bloom's syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
2 June 2018
Short dysfunctional telomeres impair the repair of arsenite-induced oxidative damage in mouse cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
27 November 2018
ATR and ATM-dependent movement of BLM helicase during replication stress ensures optimal ATM activation and 53BP1 focus formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
27 November 2018
Telomere dysfunction: a potential cancer predisposition factor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
27 November 2018
Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
27 November 2018
Drosophila BLM in double-strand break repair by synthesis-dependent strand annealing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368089
retrieved
27 November 2018
Telomere end-replication problem and cell aging
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21689668
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Effects of hTERT on metal ion-induced genomic instability
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21689668
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Possible involvement of RecQL4 in the repair of double-strand DNA breaks in Xenopus egg extracts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21689668
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Association between oxidative DNA damage and telomere shortening in circulating endothelial progenitor cells obtained from metabolic syndrome patients with coronary artery disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21689668
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
DNA end-joining: from yeast to man
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21689668
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The human Rothmund-Thomson syndrome gene product, RECQL4, localizes to distinct nuclear foci that coincide with proteins involved in the maintenance of genome stability
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21689668
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21689668
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Lack of WRN results in extensive deletion at nonhomologous joining ends
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21689668
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
[Rothmund-Thomson syndrome, trisomy 8 mosaicism and RECQ4 gene mutation]
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21689668
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.MRFMMM.2011.06.002
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/77cnfsdicrfx3kczmca3b2xz64
retrieved
30 July 2022
based on heuristic
mapped directly with Wikidata item
Fatcat ID
release_77cnfsdicrfx3kczmca3b2xz64
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/77cnfsdicrfx3kczmca3b2xz64
retrieved
30 July 2022
based on heuristic
mapped directly with Wikidata item
PMCID
3368089
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/77cnfsdicrfx3kczmca3b2xz64
retrieved
30 July 2022
based on heuristic
mapped directly with Wikidata item
PubMed ID
21689668
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/77cnfsdicrfx3kczmca3b2xz64
retrieved
30 July 2022
based on heuristic
mapped directly with Wikidata item
ResearchGate publication ID
51235008
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