(Q37998450)

26 August 2017

title

Stem cells of the human epidermis and their niche: composition and function in epidermal regeneration and carcinogenesis (English)

1 reference

26 August 2017

1 reference

Karsten Boehnke

1

1 reference

26 August 2017

Berit Falkowska-Hansen

series ordinal

2

1 reference

26 August 2017

Hans-Jürgen Stark

series ordinal

3

1 reference

26 August 2017

Petra Boukamp

series ordinal

4

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26 August 2017

language of work or name

English

0 references

publication date

29 March 2012

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26 August 2017

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26 August 2017

volume

33

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26 August 2017

issue

7

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26 August 2017

page(s)

1247-1258

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Epithelial stem cells: a folliculocentric view

26 August 2017

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A stable niche supports long-term maintenance of human epidermal stem cells in organotypic cultures

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Stem-cell niches: it's the ecology, stupid!

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Extensive tissue-regenerative capacity of neonatal human keratinocyte stem cells and their progeny

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Basement membranes: structure, assembly and role in tumour angiogenesis

21 January 2018

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Basement membrane proteoglycans: from cellar to ceiling

21 January 2018

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Integrin and basement membrane normalization in mouse grafts of human keratinocytes--implications for epidermal homeostasis

21 January 2018

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Signaling via beta1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro

21 January 2018

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Out of Eden: stem cells and their niches

21 January 2018

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The extracellular matrix: a dynamic niche in cancer progression

21 January 2018

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A review of tissue-engineered skin bioconstructs available for skin reconstruction

21 January 2018

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Artificial skin in perspective: concepts and applications

21 January 2018

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Regeneration of squamous epithelia from stem cells of cultured grafts.

21 January 2018

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Effects of fibroblasts and microenvironment on epidermal regeneration and tissue function in long-term skin equivalents

21 January 2018

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Keratinocytes express fibrillin and assemble microfibrils: implications for dermal matrix organization

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Expression of microfibril-associated glycoprotein-1 (MAGP-1) in human epidermal keratinocytes

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Authentic fibroblast matrix in dermal equivalents normalises epidermal histogenesis and dermoepidermal junction in organotypic co-culture

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

The birth of therapy with cultured cells

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Wnt signaling, lgr5, and stem cells in the intestine and skin

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate

21 January 2018

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Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin.

21 January 2018

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Tcf3: a transcriptional regulator of axis induction in the early embryo

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

The multifaceted adult epidermal stem cell

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin

21 January 2018

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Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells

21 January 2018

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Getting under the skin of epidermal morphogenesis

21 January 2018

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Stem cell niches in mammals.

21 January 2018

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Differential sensitivity of epidermal cell subpopulations to beta-catenin-induced ectopic hair follicle formation

21 January 2018

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Molecular mechanisms regulating hair follicle development

21 January 2018

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The secret life of the hair follicle

21 January 2018

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Scratching the surface of skin development

21 January 2018

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Molecular principles of hair follicle induction and morphogenesis

21 January 2018

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Epidermal stem cells of the skin

21 January 2018

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Building epithelial tissues from skin stem cells

21 January 2018

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At the roots of a never-ending cycle.

21 January 2018

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In search of the "hair cycle clock": a guided tour

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Notch signaling: its role in epidermal homeostasis and in the pathogenesis of skin diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Epidermal Notch signalling: differentiation, cancer and adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

p63 is a p53 homologue required for limb and epidermal morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

p63 regulates proliferation and differentiation of developmentally mature keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Notch1 is essential for postnatal hair follicle development and homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Notch/RBP-J signaling regulates epidermis/hair fate determination of hair follicular stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

The epidermal growth factor receptor system in skin repair and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Targeting the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Skin stem cells: rising to the surface

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Mutual induction of growth factor gene expression by epidermal-dermal cell interaction

21 January 2018

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Increased keratinocyte proliferation by JUN-dependent expression of PTN and SDF-1 in fibroblasts

21 January 2018

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A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling

21 January 2018

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Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

A decisive function of transforming growth factor-β/Smad signaling in tissue morphogenesis and differentiation of human HaCaT keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Genetic tumor archeology: microdissection and genetic heterogeneity in squamous and basal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

UV-induced skin cancer: similarities--variations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Non-melanoma skin cancer: what drives tumor development and progression?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Molecular pathology in basal cell cancer with p53 as a genetic marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

A perspective on murine keratinocyte stem cells as targets of chemically induced skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Evidence that the centrally and peripherally located cells in the murine epidermal proliferative unit are two distinct cell populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Basal cell carcinoma: cell of origin, cancer stem cell hypothesis and stem cell markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Hedgehog signaling in skin cancers

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

G-protein-coupled receptor GPR49 is up-regulated in basal cell carcinoma and promotes cell proliferation and tumor formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Basal cell carcinomas arise from hair follicle stem cells in Ptch1(+/-) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Squamous cell carcinoma induced by ultraviolet radiation originates from cells of the hair follicle in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Defining the origins of Ras/p53-mediated squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

The cancer stem cell: premises, promises and challenges

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Cancer stem cells: mirage or reality?

21 January 2018

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Cancer stem cells: an old idea--a paradigm shift

21 January 2018

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Leukaemia stem cells and the evolution of cancer-stem-cell research.

21 January 2018

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Tumors as organs: complex tissues that interface with the entire organism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Peritumoral clefting in basal cell carcinoma: correlation of in vivo reflectance confocal microscopy and routine histology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

alpha vbeta 6 Integrin promotes the invasion of morphoeic basal cell carcinoma through stromal modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Histologic features and prognosis in pediatric medulloblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Paracrine Hedgehog signaling in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Epithelial-stromal interactions in basal cell cancer: the PDGF system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

In situ identification of genes regulated specifically in fibroblasts of human basal cell carcinoma

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Stromal expression of actin is a marker of aggressiveness in basal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Stromal fibroblasts from basal cell carcinoma affect phenotype of normal keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Nodular basal cell carcinoma is associated with increased hyaluronan homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Combined non-linear laser imaging (two-photon excitation fluorescence microscopy, fluorescence lifetime imaging microscopy, multispectral multiphoton microscopy) in cutaneous tumours: first experiences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Matrix metalloproteinases in tumor progression: focus on basal and squamous cell skin cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Increased expression of matrix metalloproteinase-3 (stromelysin-1) in cultured fibroblasts and basal cell carcinomas of nevoid basal cell carcinoma syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Stromelysin-3: a potent marker for histopathologic differentiation between desmoplastic trichoepithelioma and morphealike basal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Breast-cancer-associated stromelysin-3 gene is expressed in basal cell carcinoma and during cutaneous wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Differential expression of matrix metalloproteinase (MMP)-2, MMP-9 and tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 in non-melanoma skin cancer: implications for tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

The multi-step process of human skin carcinogenesis: a role for p53, cyclin D1, hTERT, p16, and TSP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Cyclin A and beta-catenin expression in actinic keratosis, Bowen's disease and invasive squamous cell carcinoma of the skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Linking colorectal cancer to Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Tumour-stroma interactions in colorectal cancer: converging on beta-catenin activation and cancer stemness

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

A perivascular niche for brain tumor stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Tumorigenic conversion of immortal human keratinocytes through stromal cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Reversion of tumor phenotype in surface transplants of skin SCC cells by scaffold-induced stroma modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

The role of thrombospondins 1 and 2 in the regulation of cell-matrix interactions, collagen fibril formation, and the response to injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Gain of 11q/cyclin D1 overexpression is an essential early step in skin cancer development and causes abnormal tissue organization and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Tumor suppression in human skin carcinoma cells by chromosome 15 transfer or thrombospondin-1 overexpression through halted tumor vascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Differential expression of tissue inhibitor of metalloproteinases-2 by cutaneous squamous and basal cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Molecular markers of metastasis in squamous carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Incidence and risk factors for nonmelanoma skin cancer after heart transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Catastrophic cutaneous carcinomatosis in the non-organ transplant patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Subsequent squamous- and basal-cell carcinomas in kidney-transplant recipients after the first skin cancer: cumulative incidence and risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Modeling normal and pathological processes through skin tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Tumor-stroma interactions directing phenotype and progression of epithelial skin tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Replacement of animal-derived collagen matrix by human fibroblast-derived dermal matrix for human skin equivalent products

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Mesenchyme-mediated and endogenous regulation of growth and differentiation of human skin keratinocytes derived from different body sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Modelling cancer in human skin tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Modeling tissue-specific signaling and organ function in three dimensions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Engineering tumors with 3D scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Engineering tumors: a tissue engineering perspective in cancer biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Stem cell patterning and fate in human epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Reformation of organized epidermal structure by transplantation of suspensions and cultures of epidermal and dermal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Keratinocyte-derived growth factors play a role in the formation of hypertrophic scars

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

Strain-dependent epithelial defects in mice lacking the EGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS136

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGS136

1 reference

26 August 2017

1 reference