(Q38012191)

27 August 2017

title

Protein dynamics and enzyme catalysis: the ghost in the machine? (English)

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27 August 2017

Adrian J Mulholland

3

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Jeremy N. Harvey

object named as

Jeremy N Harvey

series ordinal

2

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David R Glowacki

series ordinal

1

object named as

David R Glowacki

1 reference

27 August 2017

publication date

1 June 2012

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Biochemical Society Transactions

27 August 2017

published in

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27 August 2017

volume

40

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27 August 2017

issue

3

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27 August 2017

page(s)

515-521

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A 21st century revisionist's view at a turning point in enzymology

27 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Kemp elimination catalysts by computational enzyme design

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Enzymatic transition states and dynamic motion in barrier crossing

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Atomic description of an enzyme reaction dominated by proton tunneling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Hydrogen tunneling in enzyme reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Enzymatic H-transfer requires vibration-driven extreme tunneling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Nature of Rate-Limiting Steps in the Soybean Lipoxygenase-1 Reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Temperature-dependent isotope effects in soybean lipoxygenase-1: correlating hydrogen tunneling with protein dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Solvent effects on catalysis by Escherichia coli dihydrofolate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

The Fe-CO bond energy in myoglobin: a QM/MM study of the effect of tertiary structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Enzyme dynamics point to stepwise conformational selection in catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

From induced fit to conformational selection: a continuum of binding mechanism controlled by the timescale of conformational transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Intrinsic motions along an enzymatic reaction trajectory

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Conformational changes in the active site loops of dihydrofolate reductase during the catalytic cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Fluctuating enzymes: lessons from single-molecule studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Conformational effects in enzyme catalysis: reaction via a high energy conformation in fatty acid amide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Mechanism for alternating access in neurotransmitter transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Comment on "A stationary-wave model of enzyme catalysis" by Carlo Canepa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Relating protein motion to catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

A perspective on enzyme catalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

How enzymes work: analysis by modern rate theory and computer simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Enzyme millisecond conformational dynamics do not catalyze the chemical step

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Multidimensional tunneling, recrossing, and the transmission coefficient for enzymatic reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Kinetic isotope effects for the reactions of muonic helium and muonium with H2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Near-threshold H/D exchange in CD₃CHO photodissociation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Vibrational excitation through tug-of-war inelastic collisions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Product energy deposition of CN + alkane H abstraction reactions in gas and solution phases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

QM/MM determination of kinetic isotope effects for COMT-catalyzed methyl transfer does not support compression hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Alkene hydroboration: hot intermediates that react while they are cooling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Significance of nonstatistical dynamics in organic reaction mechanisms: time-dependent stereoselectivity in cyclopentyne-alkene cycloadditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

High-accuracy computation of reaction barriers in enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Apparent NAC effect in chorismate mutase reflects electrostatic transition state stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

The catalytic effect of dihydrofolate reductase and its mutants is determined by reorganization energies

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Compound I reactivity defines alkene oxidation selectivity in cytochrome P450cam

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Carbon tunneling from a single quantum state

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Simulations of the large kinetic isotope effect and the temperature dependence of the hydrogen atom transfer in lipoxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Origin of the temperature dependence of isotope effects in enzymatic reactions: the case of dihydrofolate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Tunneling and classical paths for proton transfer in an enzyme reaction dominated by tunneling: oxidation of tryptamine by aromatic amine dehydrogenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Good vibrations in enzyme-catalysed reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Hydride transfer reaction catalyzed by hyperthermophilic dihydrofolate reductase is dominated by quantum mechanical tunneling and is promoted by both inter- and intramonomeric correlated motions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Taking Ockham's razor to enzyme dynamics and catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Structural biology: Breaking the protein rules

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Tunneling in enzymatic and nonenzymatic hydrogen transfer reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Erratum to: “Quantum mechanical tunneling in methylamine dehydrogenase” [Chem. Phys. Lett. 347 (2001) 512–518]

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Parabolic tunneling calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

Capture of hydroxymethylene and its fast disappearance through tunnelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120047

21 January 2018

Identifiers

DOI

10.1042/BST20120047

1 reference

27 August 2017

1 reference