(Q38023192)

27 August 2017

title

A state-of-the-art overview of the effect of metabolic conjugation on the biological activity of flavonoids (English)

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27 August 2017

4

Fabiola Dionisi

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27 August 2017

Karsten Beekmann

1

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27 August 2017

Lucas Actis-Goretta

2

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27 August 2017

Peter J van Bladeren

3

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27 August 2017

Frederic Destaillats

5

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27 August 2017

Ivonne M C M Rietjens

6

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27 August 2017

publication date

12 July 2012

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27 August 2017

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27 August 2017

volume

3

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27 August 2017

issue

10

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27 August 2017

page(s)

1008-1018

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Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer

27 August 2017

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The biochemistry and medical significance of the flavonoids

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Activation of EpRE-mediated gene transcription by quercetin glucuronides depends on their deconjugation

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In vitro biological properties of flavonoid conjugates found in vivo.

21 January 2018

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Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2FO30065F

Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta.

21 January 2018

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Superoxide scavenging by polyphenols: effect of conjugation and dimerization

21 January 2018

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Glucuronidated metabolites of the flavonoid quercetin do not auto-oxidise, do not generate free radicals and do not decrease nitric oxide bioavailability.

21 January 2018

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Flavonoids as substrates and inhibitors of myeloperoxidase: molecular actions of aglycone and metabolites.

21 January 2018

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Effect of quercetin and its conjugated metabolite on the hydrogen peroxide-induced intracellular production of reactive oxygen species in mouse fibroblasts

21 January 2018

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Contrasting influences of glucuronidation and O-methylation of epicatechin on hydrogen peroxide-induced cell death in neurons and fibroblasts.

21 January 2018

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Flavonoids protect neurons from oxidized low-density-lipoprotein-induced apoptosis involving c-Jun N-terminal kinase (JNK), c-Jun and caspase-3

21 January 2018

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Neuroprotective effects of antioxidative flavonoids, quercetin, (+)-dihydroquercetin and quercetin 3-methyl ether, isolated from Opuntia ficus-indica var. saboten

21 January 2018

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Quercetin and its in vivo metabolites inhibit neutrophil-mediated low-density lipoprotein oxidation

21 January 2018

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Protective effects of quercetin and its metabolites on H2O2-induced chromosomal damage to WIL2-NS cells

21 January 2018

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Inhibitory effect of a quercetin metabolite, quercetin 3-O-beta-D-glucuronide, on lipid peroxidation in liposomal membranes

21 January 2018

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Quercetin metabolites and protection against peroxynitrite-induced oxidative hepatic injury in rats

21 January 2018

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In vitro antioxidative activity of (-)-epicatechin glucuronide metabolites present in human and rat plasma

21 January 2018

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Oxidation of LDL and its clinical implication

21 January 2018

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Effect of circulating forms of soy isoflavones on the oxidation of low density lipoprotein

21 January 2018

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Identification of quercetin 3-O-beta-D-glucuronide as an antioxidative metabolite in rat plasma after oral administration of quercetin

21 January 2018

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Properties of quercetin conjugates: modulation of LDL oxidation and binding to human serum albumin

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2FO30065F

Effect of flavonoids and vitamin E on cyclooxygenase-2 (COX-2) transcription

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2FO30065F

Monocyte-endothelial cell interaction in atherogenesis and thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Adhesion molecules and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Comparative effects of quercetin and its predominant human metabolites on adhesion molecule expression in activated human vascular endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Metabolic conversion of dietary flavonoids alters their anti-inflammatory and antioxidant properties

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2FO30065F

Intestinal drug transporters: in vivo function and clinical importance.

21 January 2018

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Interaction of hydroxycinnamic acids and their conjugates with organic anion transporters and ATP-binding cassette transporters

21 January 2018

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Update on the molecular physiology of organic anion transporters.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2FO30065F

Interaction characteristics of flavonoids with human organic anion transporter 1 (hOAT1) and 3 (hOAT3).

21 January 2018

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The effect of quercetin phase II metabolism on its MRP1 and MRP2 inhibiting potential

21 January 2018

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Divergent effects of quercetin conjugates on angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2FO30065F

Quercetin and its major metabolites selectively modulate cyclic GMP-dependent relaxations and associated tolerance in pig isolated coronary artery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

(-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Modulation of pro-survival Akt/protein kinase B and ERK1/2 signaling cascades by quercetin and its in vivo metabolites underlie their action on neuronal viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Interactions of phytoestrogens with estrogen receptors alpha and beta (III). Estrogenic activities of soy isoflavone aglycones and their metabolites isolated from human urine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

SIRT1 stimulation by polyphenols is affected by their stability and metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Dietary quercetin inhibits bone loss without effect on the uterus in ovariectomized mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Cocoa flavanols and platelet and leukocyte function: recent in vitro and ex vivo studies in healthy adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Epicatechin and its methylated metabolite attenuate UVA-induced oxidative damage to human skin fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Consequences of quercetin methylation for its covalent glutathione and DNA adduct formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Effect of quercetin conjugates on vascular permeability and expression of adhesion molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Flavonoid-serum albumin complexation: determination of binding constants and binding sites by fluorescence spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Fate of the flavonoid quercetin in human cell lines: chemical instability and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Metabolism of quercetin-7- and quercetin-3-glucuronides by an in vitro hepatic model: the role of human beta-glucuronidase, sulfotransferase, catechol-O-methyltransferase and multi-resistant protein 2 (MRP2) in flavonoid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Preparation and characterization of catechin sulfates, glucuronides, and methylethers with metabolic interest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Chemical synthesis of citrus flavanone glucuronides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Combination antiangiogenesis therapy with marimastat, captopril and fragmin in patients with advanced cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Physiologically relevant metabolites of quercetin have no effect on adhesion molecule or chemokine expression in human vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Role of quercetin and its in vivo metabolites in protecting H9c2 cells against oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Epicatechin and its in vivo metabolite, 3'-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspase-3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2FO30065F

Polyphenols and disease risk in epidemiologic studies

21 January 2018

1 reference

23 June 2024

https://opencitations.net/index/api/v1/citations/10.1093/AJCN/81.1.317S

Identifiers

DOI

10.1039/C2FO30065F

1 reference

27 August 2017

1 reference