(Q38038633)

27 August 2017

Phosphoinositide lipids and cell polarity: linking the plasma membrane to the cytocortex (English)

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27 August 2017

2

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27 August 2017

1

Michael P Krahn

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27 August 2017

1 January 2012

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27 August 2017

Essays in Biochemistry

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27 August 2017

53

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27 August 2017

15-27

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Inositol trisphosphate, a novel second messenger in cellular signal transduction

27 August 2017

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Regulation of the actin cytoskeleton by phosphatidylinositol 4-phosphate 5 kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

The phosphoinositide 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

The PI(3,5)P2 and PI(4,5)P2 interactomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

PDK1, the master regulator of AGC kinase signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Recent advances in the protein kinase B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Tumor suppressor PTEN mediates sensing of chemoattractant gradients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Feedback signaling controls leading-edge formation during chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Rho family GTPases bind to phosphoinositide kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Phosphoinositide signaling pathways: promising role as builders of epithelial cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

The PAR-aPKC system: lessons in polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

The PAR proteins: fundamental players in animal cell polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

CDC-42 controls early cell polarity and spindle orientation in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

CDC-42 regulates PAR protein localization and function to control cellular and embryonic polarity in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Membrane targeting of Bazooka/PAR-3 is mediated by direct binding to phosphoinositide lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Phosphoinositide binding by par-3 involved in par-3 localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Regulated and polarized PtdIns(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Spatial control of actin organization at adherens junctions by a synaptotagmin-like protein Btsz

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Par-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishment

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

PDZ domains of Par-3 as potential phosphoinositide signaling integrators

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

Pseudomonas aeruginosa exploits a PIP3-dependent pathway to transform apical into basolateral membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

The phosphoinositol-3-kinase-protein kinase B/Akt pathway is critical for Pseudomonas aeruginosa strain PAK internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0530015

21 January 2018

Identifiers

DOI

10.1042/BSE0530015

1 reference

27 August 2017

1 reference

PubMed ID

22928505