(Q38042679)

27 August 2017

Multidrug and toxin extrusion proteins as transporters of antimicrobial drugs (English)

1 reference

27 August 2017

1

1 reference

27 August 2017

3

Elke Schaeffeler

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author name string

Katja Damme

series ordinal

2

1 reference

PubMed ID

22970772

27 August 2017

Matthias Schwab

series ordinal

4

1 reference

PubMed ID

22970772

27 August 2017

language of work or name

English

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publication date

13 September 2012

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Expert Opinion on Drug Metabolism & Toxicology

27 August 2017

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27 August 2017

8

1 reference

27 August 2017

1565-1577

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27 August 2017

12

1 reference

The perpetual challenge of infectious diseases.

27 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Membrane transporters in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Drug transporters in drug efficacy and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

A human transporter protein that mediates the final excretion step for toxic organic cations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

The MATE proteins as fundamental transporters of metabolic and xenobiotic organic cations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Molecular identification and functional characterization of rat multidrug and toxin extrusion type transporter 1 as an organic cation/H+ antiporter in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Molecular identification and functional characterization of rabbit MATE1 and MATE2-K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Physiological and pharmacokinetic roles of H+/organic cation antiporters (MATE/SLC47A).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Characterization of the human MATE2 proton-coupled polyspecific organic cation exporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Mammalian MATE (SLC47A) transport proteins: impact on efflux of endogenous substrates and xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Functional characterization of testis-specific rodent multidrug and toxic compound extrusion 2, a class III MATE-type polyspecific H+/organic cation exporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Importance of the multidrug and toxin extrusion MATE/SLC47A family to pharmacokinetics, pharmacodynamics/toxicodynamics and pharmacogenomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

MATE1 has an external COOH terminus, consistent with a 13-helix topology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Twelve transmembrane helices form the functional core of mammalian MATE1 (multidrug and toxin extruder 1) protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

A common 5'-UTR variant in MATE2-K is associated with poor response to metformin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Double-transfected MDCK cells expressing human OCT1/MATE1 or OCT2/MATE1: determinants of uptake and transcellular translocation of organic cations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Wide variety of locations for rodent MATE1, a transporter protein that mediates the final excretion step for toxic organic cations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Oppositely directed H+ gradient functions as a driving force of rat H+/organic cation antiporter MATE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

A novel variant of mouse MATE-1 H+/organic cation antiporter with a long hydrophobic tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Organic cation transporters in intestine, kidney, liver, and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Functional characterization of multidrug and toxin extrusion protein 1 as a facilitative transporter for fluoroquinolones

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Human multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter: functional characterization, interaction with OCT2 (SLC22A2), and single nucleotide polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Molecular determinants of ligand selectivity for the human multidrug and toxin extruder proteins MATE1 and MATE2-K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Reduced renal clearance of a zwitterionic substrate cephalexin in MATE1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Critical roles of Sp1 in gene expression of human and rat H+/organic cation antiporter MATE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Identification and characterization of novel polymorphisms in the basal promoter of the human transporter, MATE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Alterations in hepatic mRNA expression of phase II enzymes and xenobiotic transporters after targeted disruption of hepatocyte nuclear factor 4 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Tissue distribution, ontogeny and induction of the transporters Multidrug and toxin extrusion (MATE) 1 and MATE2 mRNA expression levels in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Targeted disruption of the multidrug and toxin extrusion 1 (mate1) gene in mice reduces renal secretion of metformin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Deficiency of multidrug and toxin extrusion 1 enhances renal accumulation of paraquat and deteriorates kidney injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Disruption of multidrug and toxin extrusion MATE1 potentiates cisplatin-induced nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Loss of multidrug and toxin extrusion 1 (MATE1) is associated with metformin-induced lactic acidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Preclinical and clinical evidence for the collaborative transport and renal secretion of an oxazolidinone antibiotic by organic anion transporter 3 (OAT3/SLC22A8) and multidrug and toxin extrusion protein 1 (MATE1/SLC47A1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Human organic anion transporters and human organic cation transporters mediate renal antiviral transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Differential contribution of organic cation transporters, OCT2 and MATE1, in platinum agent-induced nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Pharmacogenetics of antimalarial drugs: effect on metabolism and transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Pyrimethamine inhibits renal secretion of creatinine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Clinical Pharmacokinetics of Metformin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Prediction of fluoroquinolone-induced elevation in serum creatinine levels: a case of drug-endogenous substance interaction involving the inhibition of renal secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Pharmacokinetic interactions between ritonavir and quinine in healthy volunteers following concurrent administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Identification of multidrug and toxin extrusion (MATE1 and MATE2-K) variants with complete loss of transport activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Heterozygous variants of multidrug and toxin extrusions (MATE1 and MATE2-K) have little influence on the disposition of metformin in diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Genetic variation in the proximal promoter of ABC and SLC superfamilies: liver and kidney specific expression and promoter activity predict variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

DNA methylation profiles of organic anion transporting polypeptide 1B3 in cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Involvement of human multidrug and toxin extrusion 1 in the drug interaction between cimetidine and metformin in renal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Molecular mechanism of renal tubular secretion of the antimalarial drug chloroquine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: a preliminary study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2012.722996

10.1517/17425255.2012.722996

21 January 2018

Identifiers

DOI

1 reference

27 August 2017

1 reference

PubMed ID

22970772