Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q38043799)
Watch
English
Elements of ribosomal drug resistance and specificity.
scientific article published on 13 September 2012
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
5560274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22981944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
title
Elements of ribosomal drug resistance and specificity
(English)
1 reference
stated in
Europe PubMed Central
PMCID
5560274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22981944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
author
Yury Polikanov
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
5560274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22981944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
author name string
Gregor M Blaha
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
5560274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22981944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
Thomas A Steitz
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
5560274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22981944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
13 September 2012
1 reference
stated in
Europe PubMed Central
PMCID
5560274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22981944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
published in
Current Opinion in Structural Biology
1 reference
stated in
Europe PubMed Central
PMCID
5560274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22981944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
volume
22
1 reference
stated in
Europe PubMed Central
PMCID
5560274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22981944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
issue
6
1 reference
stated in
Europe PubMed Central
PMCID
5560274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22981944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
page(s)
750-758
1 reference
stated in
Europe PubMed Central
PMCID
5560274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22981944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
cites work
A new understanding of the decoding principle on the ribosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
The Antibiotic Thermorubin Inhibits Protein Synthesis by Binding to Inter-Subunit Bridge B2a of the Ribosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Macrolide antibiotics in the ribosome exit tunnel: species-specific binding and action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Crystal structure of the eukaryotic 60S ribosomal subunit in complex with initiation factor 6
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Molecular basis for the selectivity of antituberculosis compounds capreomycin and viomycin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Revisiting the structures of several antibiotics bound to the bacterial ribosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Pharmacologic effects on mitochondrial function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
The A-Z of bacterial translation inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Mitochondrial deafness alleles confer misreading of the genetic code
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Mutation from guanine to adenine in 25S rRNA at the position equivalent to E. coli A2058 does not confer erythromycin sensitivity in Sacchromyces cerevisae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Antimicrobial agents targeting the ribosome: the issue of selectivity and toxicity - lessons to be learned
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
The Structures of Antibiotics Bound to the E Site Region of the 50 S Ribosomal Subunit of Haloarcula marismortui: 13-Deoxytedanolide and Girodazole
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Reversible inhibition of mitochondrial protein synthesis during linezolid-related hyperlactatemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Structure of the 70S ribosome complexed with mRNA and tRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Species-specific antibiotic-ribosome interactions: implications for drug development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Structures of the bacterial ribosome at 3.5 A resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
The bacterial ribosome as a target for antibiotics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Structural insights into translational fidelity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Maternally inherited aminoglycoside-induced and nonsyndromic deafness is associated with the novel C1494T mutation in the mitochondrial 12S rRNA gene in a large Chinese family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
The structures of four macrolide antibiotics bound to the large ribosomal subunit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
The comparative RNA web (CRW) site: an online database of comparative sequence and structure information for ribosomal, intron, and other RNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Recognition of cognate transfer RNA by the 30S ribosomal subunit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Macrolide resistance conferred by base substitutions in 23S rRNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
The structural basis of ribosome activity in peptide bond synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Aminoglycoside antibiotics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Proposed molecular and cellular mechanism for aminoglycoside ototoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
6 September 2017
Chloramphenicol: relation of structure to activity and toxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
14 September 2017
Drastic alteration of cycloheximide sensitivity by substitution of one amino acid in the L41 ribosomal protein of yeasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
14 September 2017
Throwing a spanner in the works: antibiotics and the translation apparatus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
28 September 2017
Antibiotic Susceptibility of the Peptidyl Transferase Locus of Bovine Mitochondrial Ribosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
28 September 2017
Insensitivity of archaebacterial ribosomes to protein synthesis inhibitors. Evolutionary implications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
28 September 2017
Structural basis for selectivity and toxicity of ribosomal antibiotics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
23 June 2018
Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
23 June 2018
Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
23 June 2018
Enhanced SnapShot: Antibiotic inhibition of protein synthesis II.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
31 August 2018
Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics in Mycobacterium smegmatis by perturbation of the drug binding pocket
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
31 August 2018
Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
31 August 2018
Mitochondrial ribosomal RNA mutation associated with both antibiotic-induced and non-syndromic deafness
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
31 August 2018
The theoretical basis of Paul Ehrlich's chemotherapy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5560274
retrieved
31 August 2018
Misreading of ribonucleic acid code words induced by aminoglycoside antibiotics. The effect of drug concentration
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22981944
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Antibiotic effects on mitochondrial translation and in patients with mitochondrial translational defects
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22981944
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The Sensitivity of Rat Liver and Yeast Mitochondrial Ribosomes to Inhibitors of Protein Synthesis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22981944
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Induction of translational errors (misreading) by tuberactinomycins and capreomycins
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22981944
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.SBI.2012.07.016
1 reference
stated in
Europe PubMed Central
PMCID
5560274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22981944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
PMCID
5560274
1 reference
stated in
Europe PubMed Central
PMCID
5560274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22981944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
PubMed ID
22981944
1 reference
stated in
Europe PubMed Central
PMCID
5560274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22981944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
ResearchGate publication ID
230862666
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
