(Q38044958)

27 August 2017

Pharmacotherapy in pregnancy; effect of ABC and SLC transporters on drug transport across the placenta and fetal drug exposure (English)

1 reference

27 August 2017

0 references

Frantisek Staud

1

1 reference

PubMed ID

22994411

27 August 2017

Lukas Cerveny

series ordinal

2

1 reference

PubMed ID

22994411

27 August 2017

Martina Ceckova

series ordinal

3

1 reference

27 August 2017

20 September 2012

1 reference

Journal of Drug Targeting

27 August 2017

1 reference

27 August 2017

20

1 reference

27 August 2017

736-763

1 reference

27 August 2017

9

1 reference

Anatomical, physiological and metabolic changes with gestational age during normal pregnancy: a database for parameters required in physiologically based pharmacokinetic modelling.

27 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Insight into the cooperation of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) at the blood-brain barrier: a case study examining sorafenib efflux clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Synchronized activity of organic cation transporter 3 (Oct3/Slc22a3) and multidrug and toxin extrusion 1 (Mate1/Slc47a1) transporter in transplacental passage of MPP+ in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Prominent expression of xenobiotic efflux transporters in mouse extraembryonic fetal membranes compared with placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

P-glycoprotein: from genomics to mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Prenatal Therapy of a Patient with Vitamin-B12-Responsive Methylmalonic Acidemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Antiepileptic medication during pregnancy: does fetal genotype affect outcome?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Role of MDR1 and MRP1 in trophoblast cells, elucidated using retroviral gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Controlling drug delivery across the placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Effect of the size of liposomes on the transfer and uptake of carboxyfluorescein by the perfused human term placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Endocytotic uptake of small unilamellar liposomes by human trophoblast cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Carbamazepine uptake into rat brain following intra-olfactory transport

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Epidemiology of gestational diabetes mellitus and its association with Type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Protease inhibitors atazanavir, lopinavir and ritonavir are potent blockers, but poor substrates, of ABC transporters in a broad panel of ABC transporter-overexpressing cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The role of multidrug transporters in drug availability, metabolism and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Drug use in pregnancy: an overview of epidemiological (drug utilization) studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Emtricitabine: Inhibitor and substrate of multidrug resistance associated protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Quantitative expression patterns of multidrug-resistance P-glycoprotein (MDR1) and differentially spliced cystic-fibrosis transmembrane-conductance regulator mRNA transcripts in human epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Transport of organic anions across the basolateral membrane of proximal tubule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Comparative aspects of trophoblast development and placentation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

P-glycoprotein in the placenta: expression, localization, regulation and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Expression and functional activity of breast cancer resistance protein (BCRP, ABCG2) transporter in the human choriocarcinoma cell line BeWo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Adaptations in placental nutrient transfer capacity to meet fetal growth demands depend on placental size in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Metformin in management of pregnant insulin-independent diabetics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

UDP-glucuronosyltransferase activity, expression and cellular localization in human placenta at term

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Pharmacological management of gestational diabetes: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Role of breast cancer resistance protein (Bcrp/Abcg2) in fetal protection during gestation in rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Transplacental pharmacokinetics of glyburide, rhodamine 123, and BODIPY FL prazosin: effect of drug efflux transporters and lipid solubility.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Prevention of mother-to-child HIV transmission in resource-poor countries: translating research into policy and practice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Intranasal delivery to the central nervous system: mechanisms and experimental considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

A multidrug resistance transporter from human MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

OCTN3: A Na+-independent L-carnitine transporter in enterocytes basolateral membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Insignificant transfer of glyburide occurs across the human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Comparative placental structure

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Effect of breast cancer resistance protein (Bcrp/Abcg2) on the disposition of phytoestrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Expression and distribution of nucleoside transporter proteins in the human syncytiotrophoblast.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The ABC transporter BCRP/ABCG2 is a placental survival factor, and its expression is reduced in idiopathic human fetal growth restriction.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

ABC drug transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblast

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Clinical therapeutics in pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Pharmacokinetics and safety of single-dose tenofovir disoproxil fumarate and emtricitabine in HIV-1-infected pregnant women and their infants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Indinavir/low-dose ritonavir containing HAART in HIV-1 infected children has potent antiretroviral activity, but is associated with side effects and frequent discontinuation of treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Role of transporters in placental transfer of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Colloidal carriers and blood-brain barrier (BBB) translocation: a way to deliver drugs to the brain?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The placenta and gestational diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Breast cancer resistance protein: mediating the trans-placental transfer of glyburide across the human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Designing pregnancy centered medications: drugs which do not cross the human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Membrane transporters in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Precision-cut slice culture method for rat placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Importance of P-glycoprotein for drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Cloning and characterization of two human polyspecific organic cation transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Expression, localization, and function of the carnitine transporter octn2 (slc22a5) in human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Organic anion transporting polypeptide 2B1 and breast cancer resistance protein interact in the transepithelial transport of steroid sulfates in human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Drug excretion mediated by a new prototype of polyspecific transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Fetoprotective activity of breast cancer resistance protein (BCRP, ABCG2): expression and function throughout pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

High-dose nevirapine: safety, pharmacokinetics, and antiviral effect in patients with human immunodeficiency virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Role of human placental apical membrane transporters in the efflux of glyburide, rosiglitazone, and metformin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Comparative safety of antiepileptic drugs during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Functional characterization of testis-specific rodent multidrug and toxic compound extrusion 2, a class III MATE-type polyspecific H+/organic cation exporter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The inhibitory effects of fluoroquinolones on L-carnitine transport in placental cell line BeWo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Population pharmacokinetics of emtricitabine in human immunodeficiency virus type 1-infected pregnant women and their neonates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Regulation of protein expression and function of octn2 in forskolin-induced syncytialization in BeWo Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Prenatal pharmacotherapy for fetal anomalies: a 2011 update.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The human placental perfusion model: a systematic review and development of a model to predict in vivo transfer of therapeutic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Placental P-glycoprotein and breast cancer resistance protein: influence of polymorphisms on fetal drug exposure and physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Maternal-fetal transfer and amniotic fluid accumulation of nucleoside analogue reverse transcriptase inhibitors in human immunodeficiency virus-infected pregnant women

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Functional significance of genetic polymorphisms in P-glycoprotein (MDR1, ABCB1) and breast cancer resistance protein (BCRP, ABCG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Transport of drugs from the nasal cavity to the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Drugs dispensed in primary care during pregnancy: a record-linkage analysis in Tayside, Scotland.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Transplacental treatment of fetal tachycardia: implications of drug transporting proteins in placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Effects of drugs on the fetus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the organic cation transporter 1 (Oct1 [Slc22a1]) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Multidrug resistance in Staphylococcus aureus due to overexpression of a novel multidrug and toxin extrusion (MATE) transport protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Serum levels of lamotrigine during delivery in mothers and their infants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Multidrug resistance phosphoglycoprotein (ABCB1) in the mouse placenta: fetal protection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Multidrug resistance proteins (MRPs, ABCCs): importance for pathophysiology and drug therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The complexities of antiretroviral drug-drug interactions: role of ABC and SLC transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Xenobiotic, bile acid, and cholesterol transporters: function and regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Transport of carnitine and acetylcarnitine by carnitine/organic cation transporter (OCTN) 2 and OCTN3 into epididymal spermatozoa.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Organic anion transporter oatp2-mediated interaction between digoxin and amiodarone in the rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The SLC22 drug transporter family

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Organic cation transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Expression and function of ABCB1 and ABCG2 in human placental tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Glyburide and fetal safety; transplacental pharmacokinetic considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Determination of metformin transfer across the human placenta using a dually perfused ex vivo placental cotyledon model.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Carrier-mediated transport of metformin across the human placenta determined by using the ex vivo perfusion of the placental cotyledon model

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Pharmacokinetic assessment of multiple ATP-binding cassette transporters: the power of combination knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

L-Carnitine transport in human placental brush-border membranes is mediated by the sodium-dependent organic cation transporter OCTN2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Interactions of nucleoside analogs, caffeine, and nicotine with human concentrative nucleoside transporters 1 and 2 stably produced in a transport-defective human cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

A comparison of glyburide and insulin in women with gestational diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The presence of xenobiotic transporters in rat placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

P-glycoprotein related drug interactions: clinical importance and a consideration of disease states

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

6-Mercaptopurine transport by equilibrative nucleoside transporters in conditionally immortalized rat syncytiotrophoblast cell lines TR-TBTs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Co-localization and interaction of human organic anion transporter 4 with caveolin-1 in primary cultured human placental trophoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Organic cation transporters: physiology, toxicology and special focus on ethidium as a novel substrate.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Characterization of the ATP-dependent leukotriene C4 export carrier in mastocytoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Tissue distribution, ontogeny and induction of the transporters Multidrug and toxin extrusion (MATE) 1 and MATE2 mRNA expression levels in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Role of P-glycoprotein in pharmacokinetics: clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Dominance of colchicine resistance in hybrid CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Sotalol permeability in cultured-cell, rat intestine, and PAMPA system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Clinical trials of intranasal delivery for treating neurological disorders--a critical review

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Drug resistance in brain diseases and the role of drug efflux transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Physiologically-based pharmacokinetic (PBPK) models for assessing the kinetics of xenobiotics during pregnancy: achievements and shortcomings

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Diagnosis, clinical features, management, and post-natal follow-up of fetal tachycardias

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Fetal arrhythmia: prenatal diagnosis and perinatal management

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

BCRP/ABCG2 in the placenta: expression, function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Uptake of 1-methyl-4-phenylpyridinium (MPP+) by the JAR human placental choriocarcinoma cell line: comparison with 5-hydroxytryptamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Transplacental passage of protease inhibitors at delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

P-glycoprotein and breast cancer resistance protein expression in human placentae of various gestational ages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Role of the multidrug transporter proteins ABCB1 and ABCC2 in the diaplacental transport of talinolol in the term human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

How can we best use structural information on P-glycoprotein to design inhibitors?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Transfer of PAMAM dendrimers across human placenta: prospects of its use as drug carrier during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Epidermal growth factor-mediated activation of the map kinase cascade results in altered expression and function of ABCG2 (BCRP).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Variable expression of MRP2 (ABCC2) in human placenta: influence of gestational age and cellular differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Transport of lamivudine [(-)-beta-L-2',3'-dideoxy-3'-thiacytidine] and high-affinity interaction of nucleoside reverse transcriptase inhibitors with human organic cation transporters 1, 2, and 3

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Pharmacokinetics of nevirapine in human immunodeficiency virus type 1-infected pregnant women and their neonates. Pediatric AIDS Clinical Trials Group Protocol 250 Team

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

MRP isoforms and BCRP mediate sulfate conjugate efflux out of BeWo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) on the brain distribution of a novel BRAF inhibitor: vemurafenib (PLX4032)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Physiological and pharmacological roles of nucleoside transporter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Functional role of P-glycoprotein in the human blood-placental barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Pharmacokinetics and antiretroviral activity of lamivudine alone or when coadministered with zidovudine in human immunodeficiency virus type 1-infected pregnant women and their offspring

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Lamotrigine use in pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Transporter-mediated drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

A phase I/II study of the safety and pharmacokinetics of nevirapine in HIV-1-infected pregnant Ugandan women and their neonates (HIVNET 006).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

ABCG2/BCRP decreases the transfer of a food-born chemical carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in perfused term human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Human placental perfusion method in the assessment of transplacental passage of antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

An examination of whether human placental perfusion allows accurate prediction of placental drug transport: studies with diazepam

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Transplacental passage of lamotrigine in a human placental perfusion system in vitro and in maternal and cord blood in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Sites of mRNA expression of the cystic fibrosis (CF) and multidrug resistance (MDR1) genes in the human placenta of early pregnancy: No evidence for complementary expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Basal Membrane Localization of MRP1 in Human Placental Trophoblast

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Proton gradient-dependent transport of valproic acid in human placental brush-border membrane vesicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Role of P-glycoprotein in transplacental transfer of methadone

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Transfer of methadone across the dually perfused preterm human placental lobule

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Benefits and Risks of Oral Diabetes Agents Compared With Insulin in Women With Gestational Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Placental transfer of conjugated bisphenol A and subsequent reactivation in the rat fetus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Enhancement of zidovudine uptake by dehydroepiandrosterone sulfate in rat syncytiotrophoblast cell line TR-TBT 18d-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

P-glycoprotein expression and distribution in the rat placenta during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Functional Characterization of pH-Sensitive Organic Anion Transporting Polypeptide OATP-B in Human

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The MATE proteins as fundamental transporters of metabolic and xenobiotic organic cations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

A human transporter protein that mediates the final excretion step for toxic organic cations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Treatment of fetal tachycardia with sotalol: transplacental pharmacokinetics and pharmacodynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Mechanisms for the transport of unconjugated bilirubin in human trophoblastic BeWo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Effects of maturation on RNA transcription and protein expression of four MRP genes in human placenta and in BeWo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Variation of drug kinetics in pregnancy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Influence of P-glycoprotein on the transplacental passage of cyclosporine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Examination of the functional activity of P-glycoprotein in the rat placental barrier using rhodamine 123

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The role of placental breast cancer resistance protein in the efflux of glyburide across the human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Breast cancer resistance protein (BCRP)-mediated glyburide transport: effect of the C421A/Q141K BCRP single-nucleotide polymorphism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Genetic polymorphisms in placental transporters: implications for fetal drug exposure to oral antidiabetic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Amiodarone in treatment of fetal supraventricular tachycardia. A case report and review of literature

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Fatty acid oxidation disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Organic anion transporters of the SLC22 family: biopharmaceutical, physiological, and pathological roles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Metformin versus insulin for the treatment of gestational diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Contributions of phosphorylation to regulation of OCTN2 uptake of carnitine are minimal in BeWo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Characterization of the mechanism of zidovudine uptake by rat conditionally immortalized syncytiotrophoblast cell line TR-TBT.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Functional analysis of organic cation transporter 3 expressed in human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Influx mechanism of 2',3'-dideoxyinosine and uridine at the blood-placenta barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Expression in human trophoblast and choriocarcinoma cell lines, BeWo, Jeg-3 and JAr of genes involved in the hepatobiliary-like excretory function of the placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Effect of ursodeoxycholic acid on the impairment induced by maternal cholestasis in the rat placenta-maternal liver tandem excretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Effectiveness of sotalol as first-line therapy for fetal supraventricular tachyarrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Human placenta metabolizes fatty acids: implications for fetal fatty acid oxidation disorders and maternal liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Carnitine content and expression of mitochondrial beta-oxidation enzymes in placentas of wild-type (OCTN2(+/+)) and OCTN2 Null (OCTN2(-/-)) Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The physiological function of drug-transporting P-glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Understanding placental nutrient transfer--why bother? New biomarkers of fetal growth

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Regulation of placental transfer: the Na(+)/H(+) exchanger--a review

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Characterization of an ATP-driven H+ pump in human placental brush-border membrane vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Temporal expression profiles of organic anion transport proteins in placenta and fetal liver of the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Expression and function of p-glycoprotein in normal tissues: effect on pharmacokinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Breast cancer resistance protein (BCRP/ABCG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Expression and transport activity of breast cancer resistance protein (Bcrp/Abcg2) in dually perfused rat placenta and HRP-1 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Comparison of the inhibitory activity of anti-HIV drugs on P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Differential bidirectional transfer of indinavir in the isolated perfused human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Inhibition of placental P-glycoprotein: impact on indinavir transfer to the foetus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Expression of the multidrug resistance P-glycoprotein, (ABCB1 glycoprotein) in the human placenta decreases with advancing gestation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Targeting multidrug resistance in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Molecular and functional characterization of organic cation/carnitine transporter family in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The controversial role of ABC transporters in clinical oncology.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Physiological and pharmacokinetic roles of H+/organic cation antiporters (MATE/SLC47A).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Molecular cloning and functional expression of a rabbit renal organic cation transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The role of organic cation transporters (OCTs) in the transfer of metformin in the dually perfused human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Teratogenic effects of antiepileptic medications

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Oppositely directed H+ gradient functions as a driving force of rat H+/organic cation antiporter MATE1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Targeted disruption of the multidrug and toxin extrusion 1 (mate1) gene in mice reduces renal secretion of metformin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Functional differences in steroid sulfate uptake of organic anion transporter 4 (OAT4) and organic anion transporting polypeptide 2B1 (OATP2B1) in human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Characterization and identification of steroid sulfate transporters of human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Carrier-mediated transport of valproic acid in BeWo cells, a human trophoblast cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Experimental methods to study human transplacental exposure to genotoxic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The teratogenic risk of antiepileptic drug polytherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Evolving concepts in the management of congenital junctional ectopic tachycardia. A multicenter study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Physiological and pharmacological roles of ABCG2 (BCRP): recent findings in Abcg2 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Modulation of human BCRP (ABCG2) activity by anti-HIV drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Release of non-neuronal acetylcholine from the isolated human placenta is mediated by organic cation transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Fetal medicine and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Direct nose-to-brain transfer of morphine after nasal administration to rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Molecular and cellular physiology of renal organic cation and anion transport

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Human multidrug transporter ABCG2, a target for sensitizing drug resistance in cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Ribavirin uptake by cultured human choriocarcinoma (BeWo) cells and Xenopus laevis oocytes expressing recombinant plasma membrane human nucleoside transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Expression level of ABCG2 in the placenta decreases from the mid stage to the end of gestation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Importance of the multidrug and toxin extrusion MATE/SLC47A family to pharmacokinetics, pharmacodynamics/toxicodynamics and pharmacogenomics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Cloning and functional characterization of a rat renal organic cation transporter isoform (rOCT1A).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

The breast cancer resistance protein (Bcrp1/Abcg2) limits fetal distribution of glyburide in the pregnant mouse: an Obstetric-Fetal Pharmacology Research Unit Network and University of Washington Specialized Center of Research Study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Impaired activity of the extraneuronal monoamine transporter system known as uptake-2 in Orct3/Slc22a3-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

In situ hybridization and immunolocalization of concentrative and equilibrative nucleoside transporters in the human intestine, liver, kidneys, and placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Effects of low oxygen levels on the expression and function of transporter OCTN2 in BeWo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Transfer of repaglinide in the dually perfused human placenta and the role of organic anion transporting polypeptides (OATPs)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

Drug development for use during pregnancy: impact of the placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F1061186X.2012.716847

10.3109/1061186X.2012.716847

21 January 2018

Identifiers

DOI

1 reference

27 August 2017

1 reference

PubMed ID

22994411