(Q38046114)

27 August 2017

Harnessing monocyte-derived macrophages to control central nervous system pathologies: no longer 'if' but 'how'. (English)

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27 August 2017

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Michal Schwartz

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27 August 2017

1

Ravid Shechter

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27 August 2017

28 November 2012

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27 August 2017

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27 August 2017

229

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27 August 2017

332-346

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27 August 2017

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Intense immunosuppression in patients with rapidly worsening multiple sclerosis: treatment guidelines for the clinician

27 August 2017

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A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury

21 January 2018

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Anti-inflammatory drugs and Alzheimer disease.

21 January 2018

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Repertoire of microglial and macrophage responses after spinal cord injury

21 January 2018

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Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

21 January 2018

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The myeloid cells of the central nervous system parenchyma

21 January 2018

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Microglial cell origin and phenotypes in health and disease

21 January 2018

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Changing face of microglia

21 January 2018

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Regulation of innate immune responses in the brain

21 January 2018

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Microglial physiology: unique stimuli, specialized responses

21 January 2018

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Microglia: active sensor and versatile effector cells in the normal and pathologic brain

21 January 2018

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Why is Wallerian degeneration in the CNS so slow?

21 January 2018

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Fate mapping analysis reveals that adult microglia derive from primitive macrophages

21 January 2018

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Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats.

21 January 2018

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Immune-based therapy for spinal cord repair: autologous macrophages and beyond

21 January 2018

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Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease.

21 January 2018

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Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice

21 January 2018

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Wild-type microglia arrest pathology in a mouse model of Rett syndrome

21 January 2018

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Systemic inflammatory cells fight off neurodegenerative disease

21 January 2018

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Monocyte and macrophage heterogeneity

21 January 2018

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Alternative activation of macrophages: mechanism and functions

21 January 2018

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Exploring the full spectrum of macrophage activation

21 January 2018

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Trophic macrophages in development and disease

21 January 2018

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Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

21 January 2018

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Macrophage diversity enhances tumor progression and metastasis

21 January 2018

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Can the immune system be harnessed to repair the CNS?

21 January 2018

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Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up. Results of the third National Acute Spinal Cord Injury randomized controlled trial.

21 January 2018

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CD95-ligand on peripheral myeloid cells activates Syk kinase to trigger their recruitment to the inflammatory site.

21 January 2018

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Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice

21 January 2018

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Minocycline markedly protects the neonatal brain against hypoxic-ischemic injury

21 January 2018

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Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury

21 January 2018

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Autologous incubated macrophage therapy in acute, complete spinal cord injury: results of the phase 2 randomized controlled multicenter trial.

21 January 2018

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Complete spinal cord injury treatment using autologous bone marrow cell transplantation and bone marrow stimulation with granulocyte macrophage-colony stimulating factor: Phase I/II clinical trial

21 January 2018

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Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells

21 January 2018

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Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages.

21 January 2018

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ATP mediates rapid microglial response to local brain injury in vivo

21 January 2018

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UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

21 January 2018

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BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

21 January 2018

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Two faces of chondroitin sulfate proteoglycan in spinal cord repair: a role in microglia/macrophage activation

21 January 2018

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Bone marrow chimeric rats reveal the unique distribution of resident and recruited macrophages in the contused rat spinal cord.

21 January 2018

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A role for Nogo receptor in macrophage clearance from injured peripheral nerve

21 January 2018

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The glial scar-monocyte interplay: a pivotal resolution phase in spinal cord repair

21 January 2018

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Deficient CX3CR1 signaling promotes recovery after mouse spinal cord injury by limiting the recruitment and activation of Ly6Clo/iNOS+ macrophages

21 January 2018

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Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice

21 January 2018

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Control of microglial neurotoxicity by the fractalkine receptor

21 January 2018

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Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord

21 January 2018

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Lesional accumulation of CD163+ macrophages/microglia in rat traumatic brain injury

21 January 2018

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Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury

21 January 2018

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Brain-derived neurotrophic factor in astrocytes, oligodendrocytes, and microglia/macrophages after spinal cord injury.

21 January 2018

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Requirement of myeloid cells for axon regeneration

21 January 2018

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Monocytes form a vascular barrier and participate in vessel repair after brain injury

21 January 2018

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Ferritin stimulates oligodendrocyte genesis in the adult spinal cord and can be transferred from macrophages to NG2 cells in vivo

21 January 2018

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Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1

21 January 2018

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Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

21 January 2018

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T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening?

21 January 2018

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Facilitated monocyte-macrophage uptake and tissue distribution of superparmagnetic iron-oxide nanoparticles

21 January 2018

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Cell mediators of inflammation in the Alzheimer disease brain

21 January 2018

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Extracellular deposits of A beta produced in cultures of Alzheimer disease brain vascular smooth muscle cells.

21 January 2018

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Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

21 January 2018

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Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia

21 January 2018

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Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

21 January 2018

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Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice

21 January 2018

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Degradation of fibrillar forms of Alzheimer's amyloid beta-peptide by macrophages

21 January 2018

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Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease.

21 January 2018

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CC chemokine receptor 2 deficiency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease.

21 January 2018

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Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice

21 January 2018

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Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology

21 January 2018

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Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.

21 January 2018

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Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy.

21 January 2018

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Neuroscience: Alzheimer's disease

21 January 2018

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Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis

21 January 2018

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Selective ablation of bone marrow-derived dendritic cells increases amyloid plaques in a mouse Alzheimer's disease model.

21 January 2018

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Glatiramer acetate has no impact on disease progression in ALS at 40 mg/day: a double- blind, randomized, multicentre, placebo-controlled trial

21 January 2018

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Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9.

21 January 2018

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Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition

21 January 2018

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[The hematopoietic cytokine M-CSF as a cure for Alzheimer's disease].

21 January 2018

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Combined effects of hematopoietic progenitor cell mobilization from bone marrow by granulocyte colony stimulating factor and AMD3100 and chemotaxis into the brain using stromal cell-derived factor-1α in an Alzheimer's disease mouse model

21 January 2018

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Sialoadhesin-positive macrophages bind regulatory T cells, negatively controlling their expansion and autoimmune disease progression

21 January 2018

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Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool.

21 January 2018

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Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis

21 January 2018

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CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

21 January 2018

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Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease.

21 January 2018

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Parenchymal accumulation of CD163+ macrophages/microglia in multiple sclerosis brains

21 January 2018

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Myelin-laden macrophages are anti-inflammatory, consistent with foam cells in multiple sclerosis.

21 January 2018

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Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration.

21 January 2018

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Myelin-phagocytosing macrophages modulate autoreactive T cell proliferation

21 January 2018

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Subsets of myeloid-derived suppressor cells in tumor-bearing mice

21 January 2018

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Plasticity of Ly-6C(hi) myeloid cells in T cell regulation

21 January 2018

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Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a non-immune model of demyelination.

21 January 2018

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The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

21 January 2018

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Rejuvenation of regeneration in the aging central nervous system

21 January 2018

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Type II monocytes modulate T cell-mediated central nervous system autoimmune disease

21 January 2018

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Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1beta in human monocytes and multiple sclerosis.

21 January 2018

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Excess circulating alternatively activated myeloid (M2) cells accelerate ALS progression while inhibiting experimental autoimmune encephalomyelitis

21 January 2018

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Mechanisms and functional implications of adult neurogenesis

21 January 2018

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Cross-talk between neural stem cells and immune cells: the key to better brain repair?

21 January 2018

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How the brain repairs itself: new therapeutic strategies in inflammatory and degenerative CNS disorders

21 January 2018

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Inflammatory Blockade Restores Adult Hippocampal Neurogenesis

21 January 2018

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Inflammation regulates functional integration of neurons born in adult brain.

21 January 2018

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Inflammation is detrimental for neurogenesis in adult brain

21 January 2018

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Microglia instruct subventricular zone neurogenesis

21 January 2018

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Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation

21 January 2018

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Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells.

21 January 2018

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In vitro neuronal and glial differentiation from embryonic or adult neural precursor cells are differently affected by chronic or acute activation of microglia.

21 January 2018

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Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

21 January 2018

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Microglia modulate hippocampal neural precursor activity in response to exercise and aging.

21 January 2018

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Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis

21 January 2018

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Macrophage-mediated neuroprotection and neurogenesis in the olfactory epithelium

21 January 2018

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Macrophage depletion in the murine olfactory epithelium leads to increased neuronal death and decreased neurogenesis

21 January 2018

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CX3CL1/fractalkine regulates branching and migration of monocyte-derived cells in the mouse olfactory epithelium.

21 January 2018

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Regulation of learning and memory by meningeal immunity: a key role for IL-4

21 January 2018

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Inflammation-induced subventricular zone dysfunction leads to olfactory deficits in a targeted mouse model of multiple sclerosis.

21 January 2018

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Cxcl10 enhances blood cells migration in the sub-ventricular zone of mice affected by experimental autoimmune encephalomyelitis.

21 January 2018

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HIV-1-infected and immune-activated macrophages induce astrocytic differentiation of human cortical neural progenitor cells via the STAT3 pathway

21 January 2018

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Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway

21 January 2018

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Persistent migration of neuroblasts from the subventricular zone to the injured striatum mediated by osteopontin following intracerebral hemorrhage.

21 January 2018

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Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis

21 January 2018

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The therapeutic potential of neural stem cells

21 January 2018

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Transplanted neural stem/precursor cells instruct phagocytes and reduce secondary tissue damage in the injured spinal cord.

21 January 2018

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Toll-like receptors modulate adult hippocampal neurogenesis

21 January 2018

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Toll-like receptor 4 restricts retinal progenitor cell proliferation

21 January 2018

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Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

21 January 2018

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21 January 2018

The Hallmarks of Cancer

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Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.4106

1 reference

27 August 2017

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PubMed ID

23007711