(Q38057684)

27 August 2017

title

Cholesterol and Alzheimer's disease: a still poorly understood correlation (English)

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27 August 2017

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Roberta Ricciarelli

1

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27 August 2017

Elisa Canepa

2

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27 August 2017

Barbara Marengo

3

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27 August 2017

Umberto M Marinari

4

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27 August 2017

Giuseppe Poli

5

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27 August 2017

Maria A Pronzato

6

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27 August 2017

Cinzia Domenicotti

7

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27 August 2017

publication date

2 November 2012

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27 August 2017

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27 August 2017

volume

64

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27 August 2017

issue

12

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27 August 2017

page(s)

931-935

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Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

27 August 2017

cites work

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Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

21 January 2018

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Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

21 January 2018

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Origin of cholesterol in myelin

21 January 2018

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Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats

21 January 2018

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Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes?

21 January 2018

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Sterols in the central nervous system

21 January 2018

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Brain cholesterol: long secret life behind a barrier.

21 January 2018

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Expression of Liver X Receptor Target Genes Decreases Cellular Amyloid β Peptide Secretion

21 January 2018

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Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice

21 January 2018

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Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease

21 January 2018

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Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin

21 January 2018

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Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

21 January 2018

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Lipid rafts play an important role in A beta biogenesis by regulating the beta-secretase pathway

21 January 2018

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Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains

21 January 2018

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Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide

21 January 2018

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The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease.

21 January 2018

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Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

21 January 2018

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Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

21 January 2018

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The Amyloid Precursor Protein Has a Flexible Transmembrane Domain and Binds Cholesterol

21 January 2018

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Increased membrane cholesterol might render mature hippocampal neurons more susceptible to beta-amyloid-induced calpain activation and tau toxicity

21 January 2018

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Site-specific modification of Alzheimer's peptides by cholesterol oxidation products enhances aggregation energetics and neurotoxicity

21 January 2018

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Cholesterol potentiates beta-amyloid-induced toxicity in human neuroblastoma cells: involvement of oxidative stress

21 January 2018

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The link between altered cholesterol metabolism and Alzheimer's disease.

21 January 2018

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Oxysterols and neurodegenerative diseases.

21 January 2018

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Oxysterols, cholesterol homeostasis, and Alzheimer disease

21 January 2018

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Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol

21 January 2018

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Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

21 January 2018

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Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice

21 January 2018

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Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

21 January 2018

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Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol

21 January 2018

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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

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Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

21 January 2018

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Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease

21 January 2018

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apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain

21 January 2018

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Association of aortic atherosclerosis with cerebral beta-amyloidosis and learning deficits in a mouse model of Alzheimer's disease.

21 January 2018

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Learning and memory impairment in rats fed a high saturated fat diet

21 January 2018

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The effects of high fat diets and environmental influences on cognitive performance in rats

21 January 2018

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Studies of the effects of high fat diets on cognitive function in a rat model

21 January 2018

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Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits

21 January 2018

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Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice.

21 January 2018

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Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice.

21 January 2018

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Age-dependent rescue by simvastatin of Alzheimer's disease cerebrovascular and memory deficits.

21 January 2018

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Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease

21 January 2018

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Midlife cardiovascular risk factors and risk of dementia in late life

21 January 2018

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Serum cholesterol changes after midlife and late-life cognition: twenty-one-year follow-up study.

21 January 2018

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Impact of plasma lipids and time on memory performance in healthy elderly without dementia

21 January 2018

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Relation of plasma lipids to Alzheimer disease and vascular dementia

21 January 2018

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High total cholesterol levels in late life associated with a reduced risk of dementia.

21 January 2018

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Statins and the risk of dementia

21 January 2018

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Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

21 January 2018

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Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study.

21 January 2018

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Serum lipoprotein levels, statin use, and cognitive function in older women

21 January 2018

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Do statins reduce risk of incident dementia and Alzheimer disease? The Cache County Study.

21 January 2018

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Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial

21 January 2018

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MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

21 January 2018

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Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results.

21 January 2018

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Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe

21 January 2018

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Statins and therapy of Alzheimer's disease: questions of efficacy versus trial design

21 January 2018

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Statin Use and the Risk of Incident Dementia

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IUB.1091

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27 August 2017

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