(Q46738145)

24 December 2017

title

Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease (English)

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24 December 2017

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7

David M Holtzman

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24 December 2017

Suzanne E Wahrle

1

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24 December 2017

Hong Jiang

2

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24 December 2017

Maia Parsadanian

3

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24 December 2017

Richard E Hartman

4

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24 December 2017

Kelly R Bales

5

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24 December 2017

Steven M Paul

6

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24 December 2017

language of work or name

English

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publication date

5 October 2005

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24 December 2017

Journal of Biological Chemistry

published in

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24 December 2017

volume

280

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24 December 2017

issue

52

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24 December 2017

page(s)

43236-43242

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24 December 2017

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

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Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease

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Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

21 January 2018

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Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition

21 January 2018

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21 January 2018

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21 January 2018

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Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport and atherosclerosis

21 January 2018

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21 January 2018

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Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindred

21 January 2018

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The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

21 January 2018

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Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

21 January 2018

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Metabolism of High-Density Lipoprotein Apolipoproteins in Tangier Disease

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High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1

21 January 2018

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ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

21 January 2018

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Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain

21 January 2018

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Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease

21 January 2018

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ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo

21 January 2018

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Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

21 January 2018

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Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

21 January 2018

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Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease

21 January 2018

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Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.

21 January 2018

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Cholesterol and the biology of Alzheimer's disease.

21 January 2018

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The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor

21 January 2018

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Cellular catabolism of lipid poor apolipoprotein E via cell surface LDL receptor-related protein

21 January 2018

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The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice

21 January 2018

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Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

21 January 2018

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Expression of Liver X Receptor Target Genes Decreases Cellular Amyloid β Peptide Secretion

21 January 2018

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Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels

21 January 2018

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22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion

21 January 2018

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The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M508780200

In vivo effects of ApoE and clusterin on amyloid-beta metabolism and neuropathology

21 January 2018

1 reference

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The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508780200

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M508780200

1 reference

24 December 2017

1 reference

24 December 2017